#PVAylation

PVAylation: precision end-functionalized poly(vinyl alcohol) for site-selective bioconjugation The (bio)conjugation of polymers onto proteins enhances their pharmacokinetics and stability, most commonly using PEG (polyethylene glycol), but there is a need for alternatives. Poly(vinyl alcohol), ...

Our latest from Doug is out @chemicalscience.rsc.org @uommib.bsky.social . We introduce #PVAylation: site specific bioconjugation of PVA to proteins, bringing unique ice-binding capability as well as other benefits of polymer-conjugation. pubs.rsc.org/en/content/a...