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Posts by Institut Pasteur | 130 years of biomedical research

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💡 GenEpi-BioTrain Free Virtual Training #25
"Mobile Labs and Field Sequencing during Outbreaks"

Register 👉 bit.ly/4czIjCQ

2 free sessions: overview of mobile labs & field sequencing in outbreak response. Experts in field epidemiology & surveillance.

📅 Apr 13th & 15th 2026 | 09:00-12:00 CET

2 days ago 4 1 0 0

Our ms on re-sampling 4 years apart vibrio phage in natural environments is now out with some improvements. First, clearer evidence of cryptic population dynamics between phage and vibrio, presumably because of genetic diversity. www.nature.com/articles/s41...

4 days ago 48 21 1 0
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Live imaging mouse model of Duchenne muscular dystrophy reveals impaired migration & proliferation in muscle stem cells

📷 @sardeliza.bsky.social et al @brendan-evano.bsky.social
@tajbakhshlab.bsky.social @pasteur.fr
in @natcomms.nature.com

➡️ bpod.org.uk/archive/2026...

6 days ago 3 1 0 0
Enzymatic synthesis of glyco-DNA equipped with oligosaccharides and charged monosaccharides | ChemRxiv The therapeutic and biotechnological utility of synthetic oligonucleotides is constrained by the limited chemical diversity of canonical nucleotides and their susceptibility to nuclease degradation. Inspired by the hypermodified genomes of bacteriophages, ...

Very happy to share our pre-print on the enzymatic synthesis of DNA equipped with short oligosaccharides. Great collaboration with Marc Delarue and Laurence Mulard. Congrats to Maria Dalla Pozza and Marc!
chemrxiv.org/doi/full/10....
@pasteur.fr @ipdbsc.bsky.social @cnrs.fr

1 week ago 7 2 0 0
On June 18, the Institut Pasteur is organizing the third edition of its symposium, “Artificial Intelligence in Biology and Health”, in the Émile Duclaux lecture hall. The event will bring together researchers working at the intersection of AI with biomedical sciences to discuss opportunities and challenges in this exciting and rapidly evolving field.

On June 18, the Institut Pasteur is organizing the third edition of its symposium, “Artificial Intelligence in Biology and Health”, in the Émile Duclaux lecture hall. The event will bring together researchers working at the intersection of AI with biomedical sciences to discuss opportunities and challenges in this exciting and rapidly evolving field.

AI in Biology & Health symposium — 3rd edition

📅 June 18, 2026
📍 Institut Pasteur, Paris

Keynotes from EMBL-EBI, Inria & Max Planck Institute. Poster submissions still open.

Register ↘️ forms.office.com/Pages/Respon...

1 week ago 6 1 0 0

How diverse is bacterial immunity ?

We report in @science.org how language models allowed us to predict 2.4M antiphage proteins spanning >23K novel potential systems.
👏 @emordret.bsky.social, @alexhv.bsky.social & al doi.org/10.1126/scie...

Explore them here defensefinder.mdmlab.fr/wiki/refseq_...

1 week ago 224 109 10 3
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✅𝟭 𝘄𝗲𝗲𝗸 𝗹𝗲𝗳𝘁 𝘁𝗼 𝗮𝗽𝗽𝗹𝘆 - 𝗖𝗿𝘆𝗼-𝗘𝗧: 𝗜𝗺𝗮𝗴𝗲 𝗣𝗿𝗼𝗰𝗲𝘀𝘀𝗶𝗻𝗴 𝗳𝗼𝗿 𝗘𝗹𝗲𝗰𝘁𝗿𝗼𝗻 𝗠𝗶𝗰𝗿𝗼𝘀𝗰𝗼𝗽𝘆/𝗧𝗼𝗺𝗼𝗴𝗿𝗮𝗽𝗵𝘆 𝗣𝗮𝘀𝘁𝗲𝘂𝗿 𝗖𝗼𝘂𝗿𝘀𝗲!

Apply here 👉 lnkd.in/eD3VBXz3

⚠️ 𝗣𝗹𝗮𝗰𝗲𝘀 𝗮𝗿𝗲 𝗹𝗶𝗺𝗶𝘁𝗲𝗱.

1 week ago 2 2 0 0
Scanning électron micrograph showing a a multi ciliated cell (green) infected by SARS-CoV-2 (cyan particles). A bunch of motile cilia is being engulfed by membrane protrusions.

Scanning électron micrograph showing a a multi ciliated cell (green) infected by SARS-CoV-2 (cyan particles). A bunch of motile cilia is being engulfed by membrane protrusions.

SARS-COV-2 causes infected cells to lose their motile cilia, which may facilitate viral spread. In this infected nasal cell, one can see membrane protrusions engulfing a bunch of cilia.
Nice SEM image made by Vincent Michel. Glad it made the cover of J. Virol. 😊

doi.org/10.1128/jvi....

1 week ago 14 7 0 0
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Pesticides and Cancer: A Study Reveals the Biological Mechanisms Behind an Environmental Health Risk A new scientific study, published in Nature Health, reveals a strong link between exposure to agricultural pesticides in the environment and the risk of developing cancer.

Pesticides & cancer: risk +150% in high-exposure areas

Institut Pasteur & @ird-fr.bsky.social mapped 31 agricultural chemicals across Peru, revealing silent biological changes before cancer develops.

📄 Nature Health

1 week ago 9 5 0 1
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As part of the implementation of Pasteur 2030, the coordinators of Axis 2, Environmental Transitions and Health, invite you to this international symposium. The event gathers field and lab experts to discuss practical and strategic approaches to vector control under changing climates and environments. This event will also be an opportunity to present the future Vector-Borne Disease Center at the Pasteur Institute, a project combining scientific advances and dedicated architecture.
Two sessions

“Promoting field-based studies”
“Era post-insecticides?”

As part of the implementation of Pasteur 2030, the coordinators of Axis 2, Environmental Transitions and Health, invite you to this international symposium. The event gathers field and lab experts to discuss practical and strategic approaches to vector control under changing climates and environments. This event will also be an opportunity to present the future Vector-Borne Disease Center at the Pasteur Institute, a project combining scientific advances and dedicated architecture. Two sessions “Promoting field-based studies” “Era post-insecticides?”

Grand challenges in vector-borne diseases symposium

📅 June 5, 2026
📍 Institut Pasteur, Paris

Field & lab experts tackle vector-borne diseases in a changing climate.

Registration ↘️ research.pasteur.fr/fr/event/gra...

1 week ago 8 5 0 0

Happy to share the heroic effort of @gaellel.bsky.social to reduce our segmentation pain through EpiCure (Epithelial Curation), a napari plugin easing the curation of epithelial segmentation developed with several groups of @devstempasteur.bsky.social.
www.biorxiv.org/content/10.6...
See more 👇

2 weeks ago 42 18 1 0
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Unlock science with the Institut Pasteur MOOCs!
For nearly a decade, our experts have shared knowledge in infectious diseases, microbiology, immunology, and global health through engaging online courses, free and open to all.

👉 Explore our full catalogue : www.pasteur.fr/en/e-learnin...

2 weeks ago 7 3 1 0
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A skin colonizer disrupts inflammatory and humoral immune defenses in hidradenitis suppurativa - EMBO Molecular Medicine Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease associated with a polybacterial dysbiosis devoid of a known pathogen. Here, we report that HS patients mount IgA and IgG responses ...

Congratulations to @lguenin.bsky.social for her new publication! Check it out! 👉 link.springer.com/article/10.1...

2 weeks ago 8 3 0 0

What happens when Klebsiella's capsule locus is swapped? Unexpectedly little in terms of cell growth. Yet, it does change the bacterium's environment and interactions with it: evolution by seamless plug-and-play capsule swap. Led by @julielebris.bsky.social @olayarendueles.bsky.social

2 weeks ago 18 5 0 0
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⏳ Time is running out!

The deadline to apply for the #ASCBcourse at @InstitutPasteur is April 5th — don't miss your chance! 🚨

📍 Paris | 📆 June 22 - July 3, 2026
🔬 2 weeks | 9 modules | World-class faculty

Apply now 👉 shorturl.at/PyUHi

#StemCells #PhD #Postdoc

2 weeks ago 4 6 1 0
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Evolutionary biology: what an aquatic microorganism can tell us about our distant origins Over a period of two to three billion years, the only living beings on Earth were single-celled organisms. In what conditions did living organisms with multiple cells emerge? How did life become more ...

Choanoflagellates — our closest animal relatives — form multicellular colonies in two ways: cell division AND aggregation.

This previously unknown "mixed multicellularity" suggests our animal origins are more complex than thought.

📄 @thibautbrunet.bsky.social ↘️

2 weeks ago 45 14 0 1
The DNA Polymerase Meeting is a biennial international conference that brings together scientists from around the globe to discuss the latest discoveries in the field of DNA polymerases and their role in DNA replication and repair.

Topics will span from fundamental mechanistic insights into polymerase structure and function to cutting-edge applications in biotechnology, medicine, and synthetic biology.

DNA polymerases are not only essential for maintaining genome integrity under diverse cellular conditions, but they have also become indispensable tools in molecular biology and technology—powering PCR, sequencing, genome editing, aptamer generation and diagnostic innovations.

The past seven conferences held in Ascona, Madrid, Cambridge, Biarritz, Leiden, Stockholm, and Warsaw were extremely successful, fostering collaborations and advancing the field.

We are delighted to continue this tradition with the upcoming meeting in Paris, scheduled for Sep 28th to Oct 1st 2026.

The DNA Polymerase Meeting is a biennial international conference that brings together scientists from around the globe to discuss the latest discoveries in the field of DNA polymerases and their role in DNA replication and repair. Topics will span from fundamental mechanistic insights into polymerase structure and function to cutting-edge applications in biotechnology, medicine, and synthetic biology. DNA polymerases are not only essential for maintaining genome integrity under diverse cellular conditions, but they have also become indispensable tools in molecular biology and technology—powering PCR, sequencing, genome editing, aptamer generation and diagnostic innovations. The past seven conferences held in Ascona, Madrid, Cambridge, Biarritz, Leiden, Stockholm, and Warsaw were extremely successful, fostering collaborations and advancing the field. We are delighted to continue this tradition with the upcoming meeting in Paris, scheduled for Sep 28th to Oct 1st 2026.

🧬 8th DNA Polymerases Meeting

📅 28 Sept – 1 Oct 2026, Paris

An international conference on DNA polymerases: replication, repair, genome integrity, and applications in PCR, sequencing, genome editing and diagnostics.

Register now ↘️ www.8th-dna-polymerases.conferences-pasteur.org

2 weeks ago 10 8 0 1
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Tuberculosis (TB), caused by Mycobacterium tuberculosis, remains one of the deadliest infectious diseases worldwide. Meanwhile, non-tuberculous mycobacteria (NTM) are an increasing global health concern. NTM infections often resemble TB clinically, which can lead to misdiagnosis and inappropriate therapy. Additionally, drug-resistant strains of M. tuberculosis and NTM exacerbate the global antimicrobial resistance crisis. A better understanding of the biology of mycobacterial pathogens and of the mechanisms underlying disease pathogenesis and transmission is critical to reduce their burden worldwide.

This EMBO Workshop is the fourth in a successful series held at the Institut Pasteur in Paris, following the meetings organized in 2012, 2016, and 2022. It will bring together scientists, clinicians, public health experts, and representatives from industry and non-profit organizations, who will share recent insights into mycobacterial infections, from fundamental discoveries to translational research, and their practical implications. The program will cover mycobacterial evolution, physiology, metabolism, host–pathogen interactions, immune responses, mechanisms of drug evasion, therapeutic strategies, vaccines, and diagnostics. Emerging experimental models, computational approaches, and artificial intelligence will also be addressed, showing how recent technologies contribute to advancing mycobacterial research and interventions.

Tuberculosis (TB), caused by Mycobacterium tuberculosis, remains one of the deadliest infectious diseases worldwide. Meanwhile, non-tuberculous mycobacteria (NTM) are an increasing global health concern. NTM infections often resemble TB clinically, which can lead to misdiagnosis and inappropriate therapy. Additionally, drug-resistant strains of M. tuberculosis and NTM exacerbate the global antimicrobial resistance crisis. A better understanding of the biology of mycobacterial pathogens and of the mechanisms underlying disease pathogenesis and transmission is critical to reduce their burden worldwide. This EMBO Workshop is the fourth in a successful series held at the Institut Pasteur in Paris, following the meetings organized in 2012, 2016, and 2022. It will bring together scientists, clinicians, public health experts, and representatives from industry and non-profit organizations, who will share recent insights into mycobacterial infections, from fundamental discoveries to translational research, and their practical implications. The program will cover mycobacterial evolution, physiology, metabolism, host–pathogen interactions, immune responses, mechanisms of drug evasion, therapeutic strategies, vaccines, and diagnostics. Emerging experimental models, computational approaches, and artificial intelligence will also be addressed, showing how recent technologies contribute to advancing mycobacterial research and interventions.

🧬 EMBO Workshop – The complexity of mycobacterial infections: from research to real-world impact

📅 14–18 Sept 2026, Paris

Tuberculosis & non-tuberculous mycobacteria at the heart of discussions: evolution, host–pathogen interactions, drug resistance.

🔗 meetings.embo.org/event/26-myc...

2 weeks ago 8 11 1 0
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🔬 Interested in biological structures? 3 intensive cryo-EM/ET courses, led by experts and now open for applications!

⚠️ Places are limited.

Cryo-EM has transformed how we study biological molecules at high resolution. Nobel Prize in Chemistry 2017.

🔗Find all 3 courses here: https://bit.ly/4syT51G

3 weeks ago 7 3 0 0
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Two postdoctoral positions in epidemic modelling - Research Job description We are recruiting 2 postdocs to contribute to research projects in the Mathematical Modelling of Infectious Diseases Unit, at Institut Pasteur in Paris. The postdocs will develop state...

Two postdoc positions for a number of exciting epidemic modelling projects opening in my Unit at @pasteur.fr in beautiful Paris. Deadline for applications: 13th April. More details at the following link:
research.pasteur.fr/job/two-post...

3 weeks ago 12 24 0 1
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[VIE DES SCIENCES] 🔬 Jacques Monod, pionnier de la biologie moderne - Un article de Maxime Schwartz dans Vie des sciences.

--> Lire le billet : vds.hypotheses.org/22095

#Article #Histoire #Science #Biographie #Biologie
@pasteur.fr

3 weeks ago 12 3 0 1
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Local agricultural transition, crisis and migration in the Southern Andes - Nature In the Uspallata Valley, agriculture was adopted by local populations, as evidenced by genetic continuity from earlier hunter-gatherers to farmers; maize-dependent groups from the same regional p...

How did farming reach the Southern Andes? Through migration or cultural transmission? Our new paper in @nature.com combines ancient DNA, isotopes, archaeology & paleoclimate to reconstruct 2,000+ years of history in Uspallata, Mendoza.
www.nature.com/articles/s41...
A Thread🧵 (1/25+)

3 weeks ago 67 32 6 5

🦟 🦠 Notre équipe et celle de @simonlorierelab.bsky.social
au sein du laboratoire "Génomique Évolutive, Modélisation et Santé" (GEMS) @cnrsecologie.bsky.social @pasteur.fr
avons élucidé les déterminants génétiques viraux de la transmissibilité du #virus #Zika par le #moustique Aedes aegypti

3 weeks ago 12 2 0 0
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COVID-19: a new strategy under investigation to tackle all variants Scientists at the Institut Pasteur have developed an innovative strategy to combat SARS-CoV-2. Rather than targeting a virus in constant mutation, they propose blocking the gateway used by the virus t...

🔬 Covid-19: block the door, not the virus

Institut Pasteur developed B07-Fc, an alpaca-derived antibody targeting ACE2 — the viral entry point that doesn't mutate.

Effective against all tested variants. Nasal administration.
Preclinical validation needed.

📄 Nature Communications #SARS-CoV-2

3 weeks ago 40 11 1 2
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How microbes protect against allergies A study conducted by scientists from the Institut Pasteur has revealed that microbes protect the lungs from subsequently developing allergies and asthma. This long-term protection is "memorized" not b...

Microbes protect lungs from allergies — and the memory isn't stored in immune cells

Fibroblasts (structural lung cells) "remember" microbe exposure & block allergic reactions for months

📄 Nature Immunology
#Allergy

3 weeks ago 11 6 0 0
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🥼Une exposition met à l’honneur les femmes scientifiques de l’Institut Pasteur
📍A découvrir à la mairie du 15ᵉ arrondissement de Paris
📅Jusqu’au 24 mars
🎟️Entrée libre
Une belle occasion de célébrer celles qui font avancer la science & d’inspirer les futures générations de scientifiques !
@pasteur.fr

3 weeks ago 5 6 0 0
Où en est la recherche sur le cancer féminin ?
Où en est la recherche sur le cancer féminin ? YouTube video by Institut Pasteur

[Cancers féminins]

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🔎♀️ L' @pasteur.fr publie une vidéo "Où en est la recherche sur le cancer féminin ?", animée par Aurélie Chiche, chercheuse à l’Institut Pasteur

👉 www.youtube.com/shorts/7SMF_...

4 weeks ago 2 1 0 0
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Santé publique France, en lien avec les autorités sanitaires et le Centre National de Référence (CNR) des Listeria @pasteur.fr pasteur ont mené des investigations ayant permis d’identifier la source de contamination de 12 patients atteints de #listériose.

➡️ urlr.me/MqS3V7

@sante.gouv.fr

4 weeks ago 6 3 0 0
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💡GenEpi-BioTrain Free Virtual Training-Antigen Surveillance: from Evolution to Immune Escape

Join us for free virtual training on antigen evolution & immune escape (SARS-CoV-2, RSV, pneumococcus...). ECDC-funded GenEpi-BioTrain Programme.

👉 https://bit.ly/46VBSHh
📅 March 23 & 25 | 09:00-12:30 CET

4 weeks ago 3 1 0 0
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Viral Hepatitis Vous découvrirez les développements les plus récents sur la structure des virus et de leur physiopathologie, ainsi que l’épidémiologie et l’évolution clinique des différents types d’hépatite

🎓 MOOC "Viral Hepatitis" open 1 year! Registrations open on FUN.

 Enroll/Revisit 👉 https://bit.ly/4romKcM
🗓️ Registration: Jan 8, 2026 – Mar 9, 2027 

Latest developments on hepatitis viruses: structure, pathophysiology, epidemiology, clinical course. The mooc covered 5 hepatitis viruses (A/B/C/D/E)

1 month ago 4 2 0 0