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Posts by CRC1218

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👉Join the City Cycling challenge from 10 to 30 June 2026! 🚴‍♀️
Let's collect kilometers and make a difference—for our health and the climate 🌱
Sign up with the mitoCRC1218 subgroup under Gesunde Uniklinik and start pedaling!
Every km counts—are you in? 💪
www.stadtradeln.de/index.php?id...

1 day ago 1 1 0 0
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🚨Be quick! Registration is filling up fast!🚨
More than half of the registration spots for the international conference "Mitochondria Volume 3" have already been taken. Register soon if you'd like to attend this fantastic opportunity!

👉Register now: mitochondria-volume3.uni-koeln.de #mitochondria

1 week ago 2 1 0 0
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🚨 Registration is open! 🚨
Join us for "Mitochondria Vol. 3: Mitochondrial Plasticity in Metabolism and Signalling", a free-of-charge international conference organized by the CRC 1218!

🗓 When: 05–07 October 2026
📍 Where: MTI, UzK Cologne, Germany

👉 Register now: mitochondria-volume3.uni-koeln.de

2 weeks ago 6 7 0 0
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The 2-day CRC1218 PI Retreat at Schloss Burgbrohl has successfully concluded last week.
In a beautiful setting, the retreat brought together engaging scientific talks, lively discussions, and inspiring exchange.
We sincerely thank all participants for their contributions and enthusiasm!

2 weeks ago 2 0 0 0

We’re happy to announce that we’ve awarded a new Family Grant to support our postdoctoral researcher Marijana Croon (@marijanacroon.bsky.social).
The grant helps researchers balance excellent science with family responsibilities.
Congratulations, Marijana—we’re excited to support your work!

1 month ago 2 1 1 0
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1 month ago 0 1 1 0
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We’re excited to share that also this year, we’ve offset CO2 emissions for all travel grants awarded to our early career researchers in 2025! 🌱 The CRC1218 is committed to fostering scientific progress while protecting the planet🌍
#SustainableScience #ScienceForTheFuture

4 months ago 2 0 0 0

The Female Mentoring Program is a common effort together with the CRCs 1403 and 1451!
@sfb1403.bsky.social

4 months ago 0 0 0 0
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🌟 Exciting Kick-off for our Female Mentoring Program! 🌟
Last Friday our mentees kicked off their journey with a hands-on workshop, learning the core principles of effective mentoring and how to build an independent, impactful mentoring relationship. 💪✨
#WomenSupportingWomen #FemaleMentoring

4 months ago 3 1 1 0

The Female Mentoring Program is a common effort together with the CRCs 1403 and 1451!
@sfb1403.bsky.social

4 months ago 0 0 0 0

Leucine reduces E3 ubiquitine ligase cofactor SEL1L at mitochondria, elevating OMM protein abundance to enhance metabolic respiration. The labs of Thorsten Hoppe and Jan Riemer (@riemerlab.bsky.social) furthermore assign a role to this cascade in metabolic disorders and cancer across species.

5 months ago 3 0 0 0
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Leucine inhibits degradation of outer mitochondrial membrane proteins to adapt mitochondrial respiration - Nature Cell Biology Li et al. uncover a connection between metabolic cues and mitochondrial protein degradation, showing that specifically leucine stabilizes outer mitochondrial membrane proteins by inhibiting ubiquityla...

A publication rarity these days: An author list significantly shorter than the paper title!
www.nature.com/articles/s41...
Congratulations to our Advanced PostDoc Grant Awardee, Qiaochu Li (@qiaochuli.bsky.social), for her discoveries published in NCB [see thread]:

5 months ago 4 0 1 1
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The mitochondrial disulphide relay substrate FAM136A safeguards IMS proteostasis and cellular fitness The mitochondrial disulphide relay is the key machinery for import and oxidative protein folding in the mitochondrial intermembrane space. Among IMS p…

Congratulation also to the @riemerlab.bsky.social who just identified FAM136A as a new substrate of the mitochondrial disulphide relay and its implementations in IMS proteostasis and cellular fitness.
Check it out: www.sciencedirect.com/science/arti...

5 months ago 5 2 0 1
JCI - Sulfite oxidase deficiency causes persulfidation loss and hydrogen sulfide release

👉Paper alert👈
Check out the latest read from the Schwarz lab: Fu and Kohl identify persulfidation loss and hydrogen sulfide release as consequence of full-body SOX-deficiency in mice. Congratulations to everybody involved!👏
www.jci.org/articles/vie...

5 months ago 1 0 0 0
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Ubiquitin precursor with C-terminal extension promotes proteostasis and longevity Ubiquitin is a conserved modifier regulating the stability and function of numerous target proteins. In all eukaryotes, polyubiquitin precursors are g…

📣Publication alert📣
A wonderful collaborative effort of the CRC 1218:
The lab of Mafalda Escobar-Henriques reveals that C-terminally extended ubiquitin (CxUb) is essential for mitophagy, proteostasis and longevity through a previously undefined CxUb-Ufd2 axis.
www.sciencedirect.com/science/arti...

5 months ago 1 0 0 0
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A big thank you to Thomas Splettstößer for leading an insightful Adobe Illustrator workshop on visual communication in science for our PhDs & PostDocs! We’re excited to apply what we’ve learned! 🙌
#AdobeIllustrator #VisualCommunication #Science #WorkshopSuccess

7 months ago 1 0 0 1

Publication alert! Congratulations to everybody involved in this collaborative effort👏

8 months ago 3 0 0 0
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@crc1678.bsky.social, @annamariaregina.bsky.social, @franziskaottens.bsky.social, @riemerlab.bsky.social, it was a pleasure organizing this with you!

8 months ago 3 0 0 0
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🌟 What an incredible event! Amazing location & fantastic science. 🌟
Our Graduation Symposium PhDone last Friday was a great success!
Huge thanks to our speakers for their insightful and emotional presentations, and to everyone for the valuable networking.
#ECR #mitoCRC #PhDone

8 months ago 7 3 1 1

A common effort together with the CRCs 1403 and 1451!
@sfb1403.bsky.social

8 months ago 1 0 0 0
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What an exciting step in the careers of Camilla Franchino, Deniz Savcigil and Sandrina Campos Macas, who just joined our Mentoring Program! Promoting career advancement and professional development through impactful networking. We wish you a successful journey!👩‍🔬🚀
#CareerDevelopment #WomenEmpowerment

8 months ago 1 0 1 0

@cecad.bsky.social, @crc1678.bsky.social, @sfb1403.bsky.social, Expect our challenge to beat us next year!

9 months ago 3 0 0 0
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🚴 This. was. great! 🚴‍♀️
In this year‘s #CityCycling, the #mitoCRC made it into the #Top10 of the Uniclinis, which was the best team in all of Cologne! Well done! We are really impressed by all the #sustainability enthusiasts around us!
Photo: Our youngest team member😍
#Stadtradeln #Köln #Klimaschutz

9 months ago 3 0 1 1

What an outstanding achievement by our #mitoRTG member Annamaria Regina, (@annamariaregina.bsky.social‬)! We are extremely proud of your #passion and engagement in #ScienceCommunication!
#FameLab

9 months ago 5 1 0 0

📣Lecture Announcement📣
Join us: Next Monday, the CRC 1218 and the CRC 1403, will host an interactive lecture on #ResearchDataManagement - "Folders and File Names 101: Because organising data can be hard".
Don't miss it:
🗓️ 23.06. at 10 AM
📍CECAD Lecture Hall

@sfb1403.bsky.social #datascience

10 months ago 2 1 0 0
Prof. Dr. Aleksandra Trifunovic // Max Delbrück-Preis 2025
Prof. Dr. Aleksandra Trifunovic // Max Delbrück-Preis 2025 YouTube video by UniversitaetzuKoeln

🏆We are extremely proud of our Vice Spokesperson Prof. Aleksandra Trifunovic who just received the Max Delbrück Award 2025 of @unicologne.bsky.social‬. A well-deserved recognition of her outstanding scientific achievements. Congrats!🎉
▶️ youtu.be/ayE9q9nKvyc
#mitochondria #lifescience #UniKöln

11 months ago 11 1 0 0

Congratulations to our mitoCRC project leader Prof. Jens Brüning on receiving the University Award 2024 in the category of Research of @unicologne.bsky.social in recognition of his exceptional scientific achievements!

11 months ago 14 1 0 0
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Apologies for the missing last name: Dr. Andromachi Pouikli
And recently joined Bluesky: @qiaochuli.bsky.social

11 months ago 1 0 0 0
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Big congratulations to the three awardees of our mitoCRC Advanced PostDoc Grant! We're thrilled to support Dr. Qiaochu Li, Dr. @aleksandra-zecic.bsky.social and Dr. Andromachi in their first steps toward an independent research line. Well-deserved success! 🎉
#mitochondria #PostDoc #womeninscience

11 months ago 6 0 2 2
Cell-to-mitochondria communication by regulating the translation of NEM mRNAs. The translation of NEM mRNAs serves as a crucial communication node, integrating incoming signals and output cellular responses. Translation is regulated by binding to RBPs, which respond to incoming cellular signals (e.g. mTORC1, AMPK and insulin) and control translation in both time and space. In turn, ribosomal stress caused by stalled ribosomes transmits information about mitochondrial status and initiates stress responses. Created in BioRender by Rugarli, E., 2025. https://BioRender.com/d27y662. This figure was sublicensed under CC-BY 4.0 terms.

Cell-to-mitochondria communication by regulating the translation of NEM mRNAs. The translation of NEM mRNAs serves as a crucial communication node, integrating incoming signals and output cellular responses. Translation is regulated by binding to RBPs, which respond to incoming cellular signals (e.g. mTORC1, AMPK and insulin) and control translation in both time and space. In turn, ribosomal stress caused by stalled ribosomes transmits information about mitochondrial status and initiates stress responses. Created in BioRender by Rugarli, E., 2025. https://BioRender.com/d27y662. This figure was sublicensed under CC-BY 4.0 terms.

In their Review, Eleonora Zilio, Elena Rugarli and colleagues @cecad.bsky.social @crc1218.bsky.social discuss the role of mitochondrial mRNA translation in cellular communication.
journals.biologists.com/jcs/article/...
#JCSMitoSI #Mitochondria

11 months ago 7 2 0 0