Four images to illustrate some prominent single-gene myths. Top left shows a photograph of a person deftly rolling their tongue into a U-shape. Top right shows a photograph of a person’s ear, highlighting the shape and features of the earlobe and cartilage. Bottom left shows a close-up photograph of a person’s eye, with a vivid blue colouration. Bottom right shows a photograph of a person poised to write with their left hand on the blank white page of a spiral-bound notebook.

Remember when you first learned about genetics at school? All those fascinating examples of human traits that are each apparently determined by just a single gene? Time to check in on some of your favourites to see how they’re doing. 🧬🧵🧪 1/n

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@nclark.bsky.social great talk!
Would love to talk more and would like to introduce you to one of my PhD students, John Miraszek.

@david-gokhman.bsky.social

great talk! Super interesting. Is CSGALNACT1 the correct gene name for CGAT1?
If so, I found the GWAS hits interesting.

www.ebi.ac.uk/gwas/genes/C...

Sexual dimorphism, height, educational attainment, dyslexia, math ability, and lipid measurements including cholesterol

"You too can bully your PI."
-Hiatt

"These mutations come in two flavors, neither of which taste very good."
-Dohlman
#BOG25

If you know any students interested in grad school in population/evolutionary genetics, I’ve got the funding for an MSc or PhD student in my new lab at UBC in Vancouver. Please pass it on.

Flexible on topic, but some potential projects are listed here:
tbooker.github.io/vacancies

Get in touch!

Have you all looked at diversity within an ancestry to break this confounding?

Cool talk and cool dataset!

. @laskyjr.bsky.social Diana showed higher diversity west of the Rocky Mountains compared to east of the Rockies.
But, the invasive cheatgrass in the east has one ancestry, while there are more ancestries/invasions west of the Rockies.

Import your Twitter follows to Bluesky

I imported 38 friends from Twitter to Bluesky

Jared Decker

Matching Cattle Genetics to the Environment Using Genomics l.core-apps.com/pag-2024/eve...

Session: Animal Genomics and Adaptation to Climate Change
Location: Palm 3-4
Date: Friday, Jan 12 4:05 PM

#PAG31

John Miraszek

Whole Genome Sequence Data Elucidates Signatures of Cattle Domestication and Global Bovid Migration Patterns l.core-apps.com/pag-2024/eve...

Session:
Domestication Genomics
Location: Pacific A
Date: Sunday, Jan 14 4:20 PM
#PAG31

John Miraszek

Whole Genome Sequence Data Identifies Admixture and Selection in Wild Members of the Bos Genus l.core-apps.com/pag-2024/eve...

Session: Population and Conservation Genomics 1
Location: Pacific E
Date: Saturday, Jan 13 5:30 PM
#PAG31

Decker Computaional Genomics Group is at #PAG31 !
We will have 3 presentations, headlined by my student John Miraszek.

Come join us! We have an exciting new opening for an assistant professor in the area of soil science and nutrient management at Colorado State University ! #ScienceJobs #AcademicSky #Agriculture #Soil #Agronomy #Colorado
jobs.colostate.edu/postings/137...

I'm looking to recruit a PhD student beginning in Fall 2024 to develop theory and methods for studying genotype-by-environment interactions. We're specifically interested in how GxE is affected by phenomena such as habitat choice. Please share and get in touch ASAP if interested!

So, either my letter wasn't obviously biased or chatGPT wasn't up to the task.

I know letters of recommendation can be biased. I also know machine learning models can be biased.
I asked ChatGPT to rewrite a letter I wrote for a female as if it was for a male. Surprisingly, it was quite unhelpful, only making minor changes.

I re-ran LDSC implemented in the LDER R package, artificially decreasing the sample size. Adjusting the sample size changed the h2 estimate (as expected), but the intercept stayed identical.

For me, my most creative acts come when I give my brain new information for it to make new connections.
So regardless of the mode (conference, documentary, audio book, journal article, lunch with colleague), feed your brain new info.

Clarity of writing very often reflects clarity of thought. When you see inscrutable text, particularly in your own field, there’s a good chance the authors didn’t truly understand it either

Latest from Xilin Jiang, Alkes Price, Gil McVean and co 👉 Age-dependent topic modeling of comorbidities in UK Biobank identifies disease subtypes with differential genetic risk www.nature.com/articles/s41...

.@michelnivard.bsky.social you posted on the LDSC Google Group about some simulations you did testing LDSC on output from mixed model GWA.
groups.google.com/g/ldsc_users...

The MLM affected the h2 estimate. Do you remember how the MLM affected the intercept?
#GWAS #popgen

I have heard good things about Wizards and Prophets.

A yellow embryo incubator with three tubes of media on top

Man with white hat and container with embryos in the back seat

A fence in front of a pond that warns of Danger due to Alligators and Snakes in the area

Spent 18 of my last 36 hours on the road to get these precious embryos from Florida back to Tennessee. These are the “Brahman half” of our project studying the molecular basis of heterosis in beef cattle.

Your favorite nonfiction books on Audible? Especially #science and #evolution books....

Abstract submission for #TAGC24 is open now through Nov 9! Topics include Neurogenetics, Genomes & Genomics, Ecological Genetics, plus model organism meetings, amazing keynotes, industry sessions, career/networking events & much more.
genetics-gsa.org/tagc-2024/ab...

Me and my Neanderthal cousin at the Field Museum in Chicago. 😀 According to 23andMe, I have more Neanderthal variants than 99% of their customers.