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Posts by Björn Usadel

Galaxy is really smashing it -with their training material. Here for helixer gene finding.

1 day ago 1 1 0 0
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FORGET SILICON: de.NBI Switches to 100% Organic Server Racks! 🧬🌿

We are phasing out traditional GPUs in favor of our new chlorophyll-powered compute clusters.
Please remember to water your allocated cloud partition every Tuesday.
#GreenIT #Bioinformatics #SustainableScience #DNAstorage #AprilFools

2 weeks ago 7 4 0 1

True green computing:-)

2 weeks ago 2 0 0 0
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Our Review "Development, Anatomy and Integrated Function of Grass Leaf Veins and Graminoid Stomata" is out doi.org/10.1146/annu...

Alec Baird and I discuss the development and function of the anatomical structures that regulate water supply (leaf veins) and water demand (stomata) in the grass leaf.

1 month ago 47 26 0 0

What an amazing development here!
@hhu.de 🤝@fz-juelich.de
Best wishes for great science - and the highest hopes for future collaborations!

1 month ago 5 2 1 0
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A molecular ‘gatekeeper’ in plants opens the door for beneficial microbes CIBSS researchers at the University of Freiburg are part of an international team that sheds light on a crucial step in the initiation of the symbiosis between plants and soil bacteria.

📢 #CIBSS research highlight!

Prof. Dr. Thomas Ott @ottlab.bsky.social helped identify SYFO2, a protein that lets legumes 🫛☘️“open the door” to nitrogen-fixing bacteria. 🦠 The team even activated it in tomato 🍅 — suggesting this symbiosis could be engineered in new crops. 🌱

🔗 kurzlinks.de/v7bi

1 month ago 32 16 1 1
Stellenausschreibungen an der Universität Heidelberg Infosystem der ZUV

Next position advertised by our cluster: We are searching for a Lab Manager running the single cell-sequencing lab at Heidelberg University.
adb.zuv.uni-heidelberg.de/info/INFO_FD...

1 month ago 13 21 0 0
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Helixer: ab initio prediction of primary eukaryotic gene models combining deep learning and a hidden Markov model - Nature Methods By leveraging both deep learning and hidden Markov models, Helixer achieves broad taxonomic coverage for ab initio gene annotation of eukaryotic genomes from fungi, plants, vertebrates and…

#ERGAReads | Helixer: ab initio prediction of primary eukaryotic gene models combining deep learning and a hidden Markov model 🧬
www.nature.com/articles/s41...
#GenomeAnnotation #Helixer @natmethods.nature.com

1 month ago 10 4 0 0
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We are very excited to share a new resource from our team: spatial subcellular proteome maps in plants! We developed an MS-based method that registers localizations of about 8000 proteins in Arabidopsis roots in a single experiment.

(1/9)
www.biorxiv.org/cgi/content/...

1 month ago 117 71 2 1
AI tool “Helixer” identifies genes in newly sequenced organisms Researchers at Forschungszentrum Jülich and Heinrich Heine University Düsseldorf have developed a tool that could significantly transform genome research: Helixer identifies genes directly from DNA se...

New AI tool “Helixer” identifies genes in newly sequenced organisms. Helixer identifies genes directly from DNA sequences.

Developed by team around @usadellab.bsky.social @fz-juelich.de, @apmweber.bsky.social , @sebtriesch.bsky.social @hhu.de et al. www.fz-juelich.de/en/news/arch...

2 months ago 12 5 1 0

KI-Tool „Helixer“ entdeckt Gene in unbekannten Organismen
Forscherinnen und Forscher des Forschungszentrums Jülich und der Heinrich-Heine-Universität Düsseldorf haben ein Werkzeug entwickelt, das die Genforschung spürbar verändern könn...
weiterlesen

2 months ago 4 1 0 0
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🆕📰‼️ #PaperCBGP

🔬 A study, co-authored by @wabniklab.bsky.social and published in Science, reveals a molecular mechanism blocking inflorescence termination

🧬 A negative feedback loop buffers the floral signal, opening the door to faster-growing & more efficient crops

📎 shorturl.at/rkPwJ

2 months ago 6 4 0 0

looks really cool!

2 months ago 1 0 0 0
Haplotype comparison of the fully phased chromosome 9 uncovers a variety of evolutionary processes. Top: Explanation of the approach to assign haplotypes to accessory nodes of the pangenome and subsequent visualization: 1. create a pangenome graph and parse its variation; 2. the graph is transformed into a sequence alignment for visualization; 3. the core and unique nodes remain unchanged, while the accessory nodes are recursively assigned to different haplotypes. Middle: Pangenome graph of the phased chromosome 9 created with Minigraph-Cactus and visualized with Bandage. The nodes of the graph are coloured based on the haplotypes assigned in the bottom panel. Bottom: Alignment of haplotypes of chromosome 9 for all phased P. effusa isolates, derived from the pangenome graph in 4 kb windows, as described in the top panel.

Haplotype comparison of the fully phased chromosome 9 uncovers a variety of evolutionary processes. Top: Explanation of the approach to assign haplotypes to accessory nodes of the pangenome and subsequent visualization: 1. create a pangenome graph and parse its variation; 2. the graph is transformed into a sequence alignment for visualization; 3. the core and unique nodes remain unchanged, while the accessory nodes are recursively assigned to different haplotypes. Middle: Pangenome graph of the phased chromosome 9 created with Minigraph-Cactus and visualized with Bandage. The nodes of the graph are coloured based on the haplotypes assigned in the bottom panel. Bottom: Alignment of haplotypes of chromosome 9 for all phased P. effusa isolates, derived from the pangenome graph in 4 kb windows, as described in the top panel.

#Plant pathogens secrete effectors to establish infections, but resistant crops select for resistance-breaking #pathogens. @mfseidl.bsky.social &co use #pangenome graph analyses of 19 resistance-breaking races of an #oomycete pathogen to identify several effectors @plosbiology.org 🧪 plos.io/4qA6nKC

3 months ago 10 2 1 0
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Happy to share our recent preprint:
"DNA-intercalating antiphage molecules trigger abortive infection through mutual destruction and synergize with bacterial immunity"

www.biorxiv.org/content/10.6...

@spp2330.bsky.social, @mibinet.bsky.social, @dfg.de @hhu.de @fzj.bsky.social

3 months ago 44 26 2 0
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As our #H2020 project enters its last month, our coordinator, @apmweber.bsky.social, reflects on the importance and potential of the GAIN4CROPS to boost crop yields! 🌻

“Our project can [contribute] to a more sustainable agriculture in Europe, but also in other places in the world.”🌍

3 months ago 12 4 2 0
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New Article: "Imputation integrates single-cell and spatial gene expression data to resolve transcriptional networks in barley shoot meristem development" rdcu.be/eYiMF

With Research Briefing rdcu.be/eYiM7

3 months ago 18 9 1 1

BARVISTA visualises gene expression in the barley shoot apical meristem with single-cell resolution

@edgardemesa.bsky.social @usadellab.bsky.social @simonrdg.bsky.social @isaiavardanega.bsky.social @plantgen-hhu.bsky.social @hhu.de @ceplas.bsky.social

www.plabipd.de/projects/han...

3 months ago 20 12 0 0
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Imputation integrates single-cell and spatial gene expression data to resolve transcriptional networks in barley shoot meristem development - Nature Plants Spatially resolved gene expression during barley development was done by integrating an scRNA-seq dataset from cells with unknown position with spatial transcriptomics. This dataset is publicly availa...

paper is out now in Nature Plants, here is a link: Imputation integrates single-cell and spatial gene expression data to resolve transcriptional networks in barley shoot meristem development. Nat. Plants (2026). doi.org/10.1038/s414...

3 months ago 62 33 0 1
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For some years we have been working on wild relatives of cultivated tomato including the green-fruited Solanum pennellii and orange-fruited Solanum cheesmaniae. These species, and other wild tomatoes, are genetically diverse and used in breeding to improve the cultivated tomato.

4 months ago 4 1 1 0
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3rd Early Career Plant Researcher Network Meeting

Calling experienced PhD students & postdocs with a passion for plant research. Present your work, connect with peers and discuss the key steps toward building an independent research career.

Apply by 23 Jan 2026
Details: www.plant-ecr-networking.eu

4 months ago 12 14 0 1

Dear Plant ECRs, don't miss this wonderful opportunity!

4 months ago 23 16 0 0

Lichen and moss are brilliant 👇💚

4 months ago 13 3 1 0
PhD position - Co-regulation structures for large-scale single-cell transcriptomics - within the HDS-LEE graduate school The Bioinformatics Division of the Institute of Biological and Geosciences (IBG-4) processes and develops methods and algorithms to achieve a fundamental understanding of high-dimensional data and pro...

Are you interested in @ceplas.bsky.social single cell data and spatial transcriptomic data analysis and inference? Then apply for this PhD position in our graduate school HDS-LEE in my group co-supervised by Prof Assent. www.fz-juelich.de/en/careers/j.... For questions don't hesitate to contact me.

4 months ago 11 11 0 0
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🚨JOB ALERT!
We’re hiring a Head of the new Imaging Facility at Goethe University Frankfurt. You’ll support researchers across disciplines, train users, and help enable cutting-edge science with high-end microscopy platforms.
tinygu.de/TknxZ
If facility-building + imaging is your thing, please apply!

4 months ago 12 19 0 1
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Sie ist lila, manchmal weiß, manchmal stachelig: die Aubergine.
Erstmals haben Forschende eine Übersicht über Gene und wichtige Eigenschaften erstellt – basierend auf 3.400 Sorten. 🧬 Das ebnet den Weg für robustere Sorten und hilft, Erträge zu sichern. 🌾🌡️
👉 www.fz-juelich.de/de/aktuelles...

4 months ago 8 3 0 0
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We are looking far and wide for this position! So if you are motivated, interested in academia, and want to explore the world of plant-virus interaction, we are ALSO happy to host you for a PhD! More detail below🔽☘️🦠

4 months ago 17 21 0 0
Symbiosome functionality in Medicago truncatula nodules requires continuous clearing of pectins from the symbiosome space - Nature Communications Here a mechanism for nitrogen fixation maintenance is identified in Medicago truncatula where two polygalacturoneases are expressed in nodules and secreted into the symbiosome space for clearing of ex...

Happy to share our latest paper: The symbiosome space needs to be continuously cleared from demethylated pectins to keep rhizobia happy. Former PostDoc Chao Su took this story with him when moving back to China and finished it off.
www.nature.com/articles/s41...
#PlantScience; @uni-freiburg.de

4 months ago 47 23 2 0
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W2-Professur für Pflanzenphysiologie (m/w/d) - Rheinland-Pfälzische Technische Universität Kaiserslautern-Landau (RPTU) Rheinland-Pfälzische Technische Universität Kaiserslautern-Landau (RPTU) bietet Stelle als W2-Professur für Pflanzenphysiologie (m/w/d) in Kaiserslautern - jetzt bewerben!

Professorship Plant Physiology. Kaiserslautern, Germany.
#PlantSciJobs #plantscijob
www.academics.de/jobs/w2-prof...

4 months ago 5 11 0 0
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W3-Universitätsprofessur Stressresilienz von Pflanzen - RWTH Aachen University RWTH Aachen University bietet Stelle als W3-Universitätsprofessur Stressresilienz von Pflanzen in Aachen - jetzt bewerben!

Professorship Stress resilience of plants. Aachen, Germany.
#PlantSciJobs #plantscijob
www.academics.de/jobs/w3-univ...

4 months ago 6 13 0 0