Great work by
@jonathankarin.bsky.social and @zoepiran
on modeling and generative design of swarm dynamics

journals.aps.org/pre/abstract...

The Menopause Cliff: What a Million Women's Lab Tests Reveal TLDR: A massive study of 300+ million lab tests from 1+ million women just proved what women have been saying for years: menopause isn't a gradual slope—it's a physiological cliff. Nearly e

We analyzed changes in physiology relative to menopause using two large scale studies that include millions of lab tests. Rather than align by age, we used statistical inference to align tests to final menstrual period. (1/2)
arunamed.com/the-menopaus...

פרק 36: חשיפת בכורה של מחקר פורץ דרך של מכון ויצמן בנושא מנפאוזה

Recommended listening. I was hosted on the podcast “Gil Hameever” to discuss our latest paper about the sudden physiological changes at menopause. The conversation is in Hebrew.
open.spotify.com/episode/0EVA...

🚨 AI in Science Fellowship Opportunities 🚨

🔹Now open: Up to 6x 4-year Independent Fellowships dedicated to AI in Science in a program supported by Schmidt Sciences and Imperial College London [@imperialcollegeldn.bsky.social].

🔗 Find out more and apply: www.imperial.ac.uk/research-and...

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My dept in London at Imperial (Bioengineering) is recruiting a group leader at Professor level 🧑‍🎓 Please RT. It's a great place with world-class expertise in all sorts of biomedical & biological engineering topics like synthetic biology. It's also not in the USA. www.imperial.ac.uk/jobs/search-...

We are organizing a conference for young researchers at the intersection between physics & biology: www.embl.org/about/info/c... @embl.org @events.embl.org @intcha.bsky.social
Please consider applying/registering -- the deadline is already in one week!

Theory predicted two kinds of fibrosis, hot and cold.
We show in vivo that hot and cold fibrosis describe heart failure, and heart attack, respectively, showing that they are very different disease states. @shovalmiyara.bsky.social @eldadtzahor.bsky.social

A computational pipeline for spatial mechano-transcriptomics - Nature Methods The authors present a computational framework that leverages mechanical force inference and spatial transcriptomics to enable analyses of the interplay between the transcriptomic and mechanical state.

🚨 Paper Alert 🚨
Absolutely delighted to share our last paper on "spatial mechano-transcriptomics" @naturemethods👇!!
www.nature.com/articles/s41...

This is why UK gov needs to invest in PhD training & cut visa costs for scientists

Long term economic growth depends on skilled people

The UK should make the most of life sciences

Another day, another funky gene regulatory network behaviour! In our latest paper, we show how the mushroom bifurcation can encode an ultra-long biochemical timer. Even more interestingly, extrinsic noise can be used to improve timing precision! 🤯
@mathsmaret.bsky.social @josepsardanyes.bsky.social

Zelensky is a wartime leader watching his people suffer and die under Russian attacks every day. To be lectured and lied to by Trump and Vance, as they defend the war criminal dictator committing these atrocities, is unimaginable agony. An everlasting shame for America.

Around the world, physicists and engineers followed suit, rapidly becoming absorbed into various military projects.

The way you were taught quantum mechanics depends on when you were a student. In Nature Reviews Physics, physicist and historian David Kaiser charts how the emphasis of quantum education has oscillated between philosophy and practicality. https://go.nature.com/40MyjiG 🔒

@urialonlab.bsky.social lab reveals a hormone circuit that explains why most HPA drugs fail for mood disorders and predicts the few that work ➡️ www.embopress.org/doi/full/10....

New year! New social media! And new job opening!! Join us on a programme leader track to start your group @mrc-lms.bsky.social! Supportive colleagues, wonderful new building and outstanding facilities! #cellidentity #sexdifferences #genesenvironment

Hierarchical Control of State Transitions in Dense Associative Memories We analyze a generalization of Modern Hopfield networks that emerges naturally in the gene regulatory networks that control cellular identity. Here gene expression patterns correspond to stored memori...

Happy to share this- we analyze the hierarchical organization of attractor landscapes in dense associative memories and how it can facilitate transitions between attractor states. We use this to explain the control of transitions between stem and differentiated identities. arxiv.org/abs/2412.11336

New preprint: Ageing is tightly reflected in longitudinal evolution of DNA methylation marks. We show that ageing also leaves a stereotypic footprint in how DNA methylation is correlated in the genome: positions that are roughly 500bp apart become more correlated. www.biorxiv.org/content/10.1...

A three-node Turing gene circuit forms periodic spatial patterns in bacteria Engineering Turing patterns has been one of the most challenging problems in synthetic biology because even tiny changes in the reaction parameters destroy patterning. Here, the authors construct a more robust three-node genetic circuit in E. coli to generate different kinds of reproducible spot and stripe patterns.

Building a capacity for making Turing patterns into bacteria. This is very cool.
www.cell.com/cell-systems...

Characterizing single-cell and spatial data structure and identifying gaps in our knowledge of their annotations by analyzing deep learning training dynamics!
Led by @jonathankarin.bsky.social and Reshef Mintz, with
@ravehlab.bsky.social

3D-reconstructed seminiferous tubules from serial testis sections

In this collaboration with Ben Simons' and Shosei Yoshida's lab, we propose a minimal mechanism for the intricate spatiotemporal dynamics of the spermatogenic wave.

Congratulations to Toshiyuki Sato (experiment) and Yuting I. Li (theory) for their outstanding work!

www.biorxiv.org/content/10.1...

Action Intent Links | Bluesky Authors, websites, and apps can use action intent links to implement "Share on Bluesky" buttons, or similar in-app actions. Logged-in users will be directed to the corresponding action view in the Blu...

We strongly suggest that academic publishers and other platforms that host research rapidly implement a Share to Bluesky button for their articles. Here's how:

docs.bsky.app/docs/advance...

#AcademicSky #HigherEd #Altmetrics

Upcoming Development Special Issue 'Lifelong Development'

Beyond the embryo: tissue maintenance, regeneration & plasticity

Guest eds: Meri Huch & Mansi Srivastava

Deadline: 15 May 2025 All article types welcome #DevBio #Regeneration #StemCells

journals.biologists.com/dev/pages/li...

Please spread! We have two openings for #PhD students interested in Developmental #Systems #Biology using #Celegans, #microscopy, and computers. Building on our recent paper in
@NatureComms
(rdcu.be/dscNm) to study Organ Growth Coordination. jobrxiv.org/job/univerit...