The new issue of @genomeresearch.bsky.social is now live. Follow the link to new research on somatic mutant alleles in bulk tumor samples, honey bee gut microbiota, and more! tinyurl.com/Genome-Res-3...
The new issue of @genomeresearch.bsky.social is now live. Follow the link to new research on chromosome engineering in 8p syndrome, convergent evolution in arid rodents, and more! tinyurl.com/Genome-Res-3...
Vulnerable to Huntington’s Disease, Nancy Wexler devoted her life to research that revealed the HD mutation and produced a test for susceptibility. Read her powerful autobiography published by CSHL Press: "My Life, My Science: Pursuing a Cure for Huntington’s Disease". Pre-order at: amz.cx/3c1w
A new issue of CSH Protocols is out!
@cshlpress.bsky.social
The cover image highlights the work by Moss et al., who describe how to use fluorescence flow cytometry and specific AuxInYeast strains to study #maize auxin perception.
⬇️Links below
The new issue of @genomeresearch.bsky.social is now live. Follow the link to new research on transposable elements in pancreatic cancer, genomic evolution in living fossils, and more! tinyurl.com/Genome-Res-3...
The new issue of @genomeresearch.bsky.social is now live. Follow the link to new research the 3D genome organization in breast cancer, assisted reproductive technology mutation rate, and more! tinyurl.com/Genome-Res-3...
The new issue of @genomeresearch is now live. Follow the link to new research on wheat centromere adaptation, Quadrupia - a G-quadruplex database, and more! tinyurl.com/Genome-Res-3...
Now Available! “Epigenetics: History, Molecules, and Diseases” cuts through hype to trace the field from its origins to today’s genomic landscape. A clear, authoritative guide to what epigenetics is—and is not.
Now in print + eBook formats: bit.ly/epigeneticsb...
Coming Soon: 'Epigenetics: History, Molecules, and Diseases' by John Greally. A clear-eyed, provocative journey through one of biology’s most captivating and misunderstood ideas. Available in print, eBook, and Kindle formats Tuesday, October 21. #Epigenetics #MolecularBiology #CellBiology #Genomics
The new issue of @genomeresearch.bsky.social is now live. Follow the link to new research on microglia in neurodegenerative diseases, intron retention in nuclear RNA complexes, and more! tinyurl.com/Genome-Res-3...
The new issue of @genomeresearch.bsky.social is now live. Follow the link to new research on HER2 isoform diversity and drug resistance in breast cancer, off-target site detection in prime editing, and more! tinyurl.com/Genome-Res-3...
The new issue of @genomeresearch.bsky.social is now live. Follow the link to new research on oxygen stress and gene regulation in the brain, a new C. elegans reference genome, and more! tinyurl.com/Genome-Res-3...
New issue of Genes & Development! Inspired by the 2025 CSHL Symposium on Aging & Senescence, this issue features a collection of Outlook, Perspective, and Review articles on the impact of aging on metabolism, immunity, reproductive health & cancer. Online now: genesdev.cshlp.org/content/39/15-16.toc
The new issue of @genomeresearch.bsky.social is now live. Follow the link to new research on single-cell multiomics of muscle response to endurance exercise, a method for Nanopore data compression, and more! tinyurl.com/Genome-Res-3...
The new issue of @genomeresearch.bsky.social is now live. Follow the link to new research on TP53 regulation of transposable elements in cancer, gut microbiome–associated protists, and more! tinyurl.com/Genome-Res-3...
Call for Papers! @genomeresearch.bsky.social is now encouraging submissions for a Special Issue on The Genetics and Genomics of Somatic Mosaicism, Guest Edited by Drs. Gilad Evrony, Eunjung (Alice) Lee, and Raheleh Rahbari. tinyurl.com/Call-for-pap... #BOG25 #KSMosaicism25 #MITS25 #somaticmosaicism
The new issue of Genome Research is now live! Follow the link to a new ultra-long nanopore sequencing toolkit, a unified analysis of atlas single-cell data, and more! tinyurl.com/Genome-Res-3...
📽️ G&D Tapes 📽️
G&D author, Jelani Lyda talks about a new study in #GenesDev by Riley et al. reporting the role of ClpCP protease and novel protein MdfA in driving metabolic differentiation and dormancy during bacterial sporulation. #OpenAccess
Learn more here:
➡️ tinyurl.com/gd352535
SF3B1: from core splicing factor to oncogenic driver — this #RNASpecialIssue article explores how SF3B1-mutant splicing drives cancer, with insights into prognosis, phenotypes & the need for targeted therapies. bit.ly/4bqmRy2
RNA-binding proteins at the crossroads of disease: Fragile X & SMA. This #RNASpecialIssue article traces how SMN complex, RNP assembly, and more emerged from curiosity-driven, collaborative RNA research. bit.ly/3Xv2hGX
SPECIAL ISSUE Part 2! This month @genomeresearch.bsky.social publishes a diverse collection of articles offering novel biological and clinical insights gained using long-read DNA and RNA sequencing technologies and other long molecule approaches.
tinyurl.com/Genome-Res-3...
Connecting genotype and phenotype in minor spliceosome diseases.
This article from the #RNASpecialIssue outlines the current structural and functional knowledge of the minor spliceosome, and discusses emerging challenges in connecting molecular dysfunctions to clinical phenotypes. bit.ly/4bt3aWz
This Perspective from the #RNASpecialIssue summarizes the current knowledge of translation dysregulation in cancer, with emphasis on the eukaryotic translation initiation factor 4F complex. It outlines recent endeavors to develop novel treatment strategies to combat cancer: bit.ly/3F4Sv8g
Adenosine-to-inosine RNA editing by ADARs, first discovered in the 1980s, plays a complex role in disease. This #RNASpecialIssue review explores current knowledge, therapeutic potential, and key unanswered questions. bit.ly/3F3Vqy1
Exploring the therapeutic potential of modulating nonsense-mediated mRNA decay.
This paper from the #RNASpecialIssue explores promising approaches employed to regulate NMD for therapeutic purposes, and highlights potential challenges in future clinical development. bit.ly/3F86Ron
This review from the #RNASpecialIssue discusses the distribution, regulation, and mechanisms of cytoplasmic polyadenylation element-binding proteins (CPEBs), highlighting their dual roles in either promoting or repressing gene expression depending on cellular context. bit.ly/41pFqhp
🧬 This National Children's Book Day, meet the tiny heroes inside us all! Stem Cells to the Rescue from CSHL Press is a science adventure that shows kids how our bodies heal. #ChildrensBookDay #STEMforKids #CSHLPress
www.cshlpress.com/default.tpl?...
Alternative splicing (AS) is vital for heart function, and its disruption is linked to disease. This #RNASpecialIssue article highlights nonsplicing roles of AS factors and proposes a novel disease mechanism involving pathogenic RNA granules and disrupted AS factor localization. bit.ly/3DkHM9d
Cytoplasmic viruses alter nuclear trafficking, causing RNA-binding proteins (RBPs) to relocate and act as antiviral defenses. This article from the #RNASpecialIssue explores host–virus interactions and the unanswered questions about their mechanisms. bit.ly/3QJOjNG
This article examines how RNA sensors bind ligands and trigger type I interferon-stimulated genes. It also explores how mutations in RNA sensors and RNA homeostasis genes are linked to autoimmune and autoinflammatory diseases. bit.ly/4bowQEb #RNASpecialIssue
