Top: Confocal micrograph of a Drosophila melanogaster larval neuromuscular junction. Motoneurons are labeled in red, while postsynaptic glutamate receptors are visualized in blue (subunit B) and yellow (subunit A). Bottom: Schematic summarising the main findings of the paper. An early manipulation (32-degree heat stress) during the critical period in the embryo stage is then followed up by assessment of synapse size and composition, nerve cell properties, and behavior in the 5-day larva.

Developing motor networks rely on brief windows of plasticity. This study identifies mitochondrial #ROS & HIF-1α as instructive signals that drive lasting #neural & #behavioral changes during these critical periods, linking #metabolism to circuit development @plosbiology.org 🧪 plos.io/4mHrWq4

How do we feel about a fully consensus based government. Every the citizen was distributed with a device with no cameras or microphones to ensure privacy, the device would have a debate platform that you can participate for and every citizen is notified of results. You would also vote with this app

I once had a dream where i was vividly tripping balls on mushrooms and I was driving a car ( I would never do that IRL). I dont rember most of the details but I woke up because I drove into a cement jersy wall, the car instead of crumpling with realistic physics kind of glitched and drove ovet it.

Hi

Incredible colors
🫢

Modern U.S. diets are high in processed foods, sugar, and omega-6 fats, which fuel chronic inflammation. Additives like MSG and excess protein boost glutamate levels, overstimulating the brain and disrupting mood, focus, and emotional balance.
#health #harmreduction #diet #usa #food #cognition

The glutamatergic system regulates learning, memory, and mood. Overactive glutamate signaling is linked to depression and addiction by causing excitotoxicity and dysregulating reward pathways. Modulating this system helps restore neural balance and emotional stability. #addiction #health #drugsky

Cognitive benefits: Agmatine may enhance learning and memory by promoting neuroplasticity, protecting neurons from excitotoxicity, and modulating key neurotransmitters like glutamate and serotonin. #nootropics #cognition #supplements

Agmatine helps with mood, anxiety, depression, and addiction through NMDA and opioid receptor modulation. It also supports neuroprotection, boosts nitric oxide for better blood flow, and may improve insulin sensitivity and workout performance. #drugs #harmreduction #drugsky #safeuse

Aniracetam’s memory/focus effects can be subtle, but the auditory boost is insane. Normally, synthesized voices blur into noise, and I drift off. On Aniracetam, I actually hear them as speech and stay locked in. #Nootropics #Aniracetam #CognitiveEnhancement #Biohacking

Meet 11-year-old Jocelynn Rojo Carranza, a young girl from Texas whose life was tragically cut short.

She died by suicide after classmates threatened to call ICE on her family.

Stop dehumanizing immigrants.

That is not America.

And POWER!
It's all about control power and cash!
Malignant narcissist don't think like we do. They actually believe that their white, entitled lives are more important.
Dems have to start fighting dirty like they are. Screw decorum.

Imagine being rich enough to do anything you want and choosing to take food and medicine from starving children to give yourself even more money.

How Trying Became Cool Again YouTube video by Nathan Zed

This video kicks ass: youtu.be/o2jzKo1RqWU?...

This Is the Way to Stop Elon Musk Senate Democrats have the power to block federal contracts to Tesla and SpaceX. It’s the path to pushing Musk out of politics.

theintercept.com/2025/02/17/e...

#3E #EndOligarchy #TeslaTakeover

Jan. 6 video evidence has 'disappeared' from public access, media coalition says A coalition of news organizations said in a court filing that video exhibits from a Jan. 6 riot case had "disappeared" from a government platform that provided access to evidence used in court.

A coalition of news organizations said in a court filing that video exhibits from a Jan. 6 riot case had "disappeared" from a government platform that provided access to evidence used in court.

Washington, D.C. yesterday. "Shut down the Senate, Shut down the Senate." Chanted for hours.

More massive #USprotests, ongoing. Sources here report, "Millions of people are getting ready as we speak to take this country back and save the USA. Their days are numbered. Stay tuned." #3E

JUST IN:

Federal judges orders HHS, CDC, and FDA to restore “by no later than 11:59 pm” today their websites and datasets to pre-January 30th status.

storage.courtlistener.com/recap/gov.us...

This economic system feeds on death itself: it thrives on expiration dates, diminishing resources, extinction, disposable fashion, multiple forms of slavery and planned obsolescence.

The Trump / Musk, Nazi normalization plot has failed for the most part due to Germany who has held mass protests against Musk and the brave citizens in Ohio that stigmergically came together to run parading Nazis out of their neigbourhood. Your actions matter and your voices can drown out the hate.

US Federal judge blocks Elon Musk's DOGE from accessing sensitive US Treasury Department material

US Judge pauses Trump administration effort to gut USAID's workforce by thousands

US judges put a pause on Musk and Trump's ongoing crime spree.

Judge Paul A. Engelmayer has temporarily blocked Elon Musk’s DOGE from accessing Treasury Department records. Meanwhile, Judge Carl Nichols has issued a temporary injunction preventing Musk and Trump from firing USAID employees.

aging well, sadly

Day 72 of nonstop national protests, in Georgia people also have jobs but they make the time to defend democracy and challenge the oligarchy.

They chant: "We don't want oligarchy, we demand democracy!"

📹 ( publikage.bsky.social ) #3E #EndOligarchy #GeorgiaProtests

A clam with a spring attached to the shell. The spring has a magnet placed above a sensor.

Hardly new info, but BSky should know:

Warsaw's water quality is monitored by eight clams with magnets attached to their shells. If contamination in the water causes the clams to close, the magnets trigger an alarm and shut off the city's water supply.
Thank you, little guardian molluscs.

🧪🌏🚰

Proclamation of the Great American Strike Join the nationwide movement to combat neo-feudalism and ensure justice, equity, and democratic participation in America.

My new favorite thing. ✊
Let Them 👏👏 Eat Cake! 👏👏
antifeudalamerica.com #antifeudalamerica

I no longer feel that my rights or the will of the people are being upheld. The democratic system has failed we live under an oligarchy. How long until secession is openly discussed? It is our right as Americans to reject a failed government. This system no longer serves the people. #democracy

the first good post i think i've ever seen from a democratic committee account