Hey Riftbounders! TL;DR (more in the thread - 1/11)

1: We're discussing card bans in the near future based on overly-dominant play patterns, but none to announce today, nor an expected date for bans.

The event was so much fun!

A special shout-out to the polish team, who made watching the top 8 in person an absolutely wild experience!

we need to talk about that Ring Super Bowl ad

Excited to see I'm not the only one determined to name software after members of the mustelid family 🦦

Hey all! We posted new Tournament Rules today (riftbound.leagueoflegends.com/en-us/news/a...) This post doesn't have a breakdown of what changed - apologies! Something formal will go up soon, but for now, I wanted to highlight the bigger changes. Big thanks to Frank for his work on the TR! (1/5)

Principal UX Writer - Riftbound

Hello friends! My team is hiring - specifically a gameplay text editor (to work on templating, rules, shepherding sets to the final line), or as Riot calls it, a UX Writer. Please read through the job description and apply if it sounds like your jam! www.riotgames.com/en/work-with...

As you all saw, Spiritforged preorders went fast today. We know it was a frustrating experience for a lot of you. Overall, we saw two major issues: first, even with ~50 percent more product than Origins, we still didn’t have enough to meet demand. (1/9)

Screenshot of an email from Florence + The machine. It reads: Everybody Scream The new album This Halloween

Continuation, it reads: The new single "Everybody Scream" out tomorrow at 12 PM ET / 5 PM BST

FUUUUUUUCK YEAAAAAAAAAH‼️

Guardian headline saying, "‘It’s terrifying’: WhatsApp AI helper mistakenly shares user’s number Chatbot tries to change subject after serving up unrelated user’s mobile to man asking for rail firm helpline"

'Meredith,' some guys ask, 'why won't you shove AI into Signal?'

Because we love privacy, and we love you, and this shit is predictable and unacceptable. Use Signal ❤️

GitHub - jmbuhr/quarto-molstar: Shortcode to embed proteins and trajectories with Mol* Shortcode to embed proteins and trajectories with Mol* - jmbuhr/quarto-molstar

You can us my quarto plugin that embedds mol* into the html output (or steal parts of the code). Contains options to do that with trajectories:

github.com/jmbuhr/quart...

Okay hear me out, what if building your protein model was a first person horror survival experience??

#MolecularNodes #b3d #GeometryNodes 🧪

A screenshot showing information for the GitHub repo "Molecular Nodes". Of importance is the counter for the number of stars which is at 999.

So who is going to be ⭐1000? #MolecularNodes

Max Planck Research Group Leader (W2) in Molecular Design We are looking for exceptional early-career scientists conducting computational research with a proven record of accomplishment. The primary focus of this call is on candidates proposing research on b...

Job alert: Join us in Mainz as

Max Planck Research Group Leader (W2) in Molecular Design

...and make your own research dreams happen on de novo design, generative models, proteins, materials ...
tinyurl.com/r2xjxnuk

@mpip-mainz.mpg.de

Wondering how to predict protein flexibility in a sec? No time to run MD simulations but want to go beyond pLDDT? Check out BBFlow
arxiv.org/html/2503.05...

Useful in particular for de novo designs.

Led by Nico Wolf & Leif Seute, w Seva, Simon, and Jan. @mpip-mainz.mpg.de @hitsters.bsky.social

A while online now already: Predict the barrier of a reaction without knowing the transition state and in the low data regime using Gaussian Process regr.

Led by Evgeni Ulanov, with Ghulam, Kai and Pascal Friederich @ KIT.
@mpip-mainz.mpg.de @hitsters.bsky.social

pubs.rsc.org/en/content/a...

Russian medical researcher at Harvard, who protested the Ukraine war, detained by ICE Kseniia Petrova's attorney said her previous arrest in Russia and social media activity "will almost certainly ensure a nice, hefty jail sentence for her" if she is deported back.

There are too many now to keep up with.

Oh, fun project!

What you will enjoy also for markdown, not just quarto, is my otter.nvim plugin for your code chunks.

I personally don't do much highlighting and concealing in the plain text format, because I don't like it when text moves around during editing due to conceals etc. The exception to that are images (only on hover), which I do like, via image.nvim.

Composite image illustrating enzyme inhibition concepts with a black dog in different poses: Top-left: The dog wears a pink flying disc on its head, labeled “Non-competitive (allosteric) inhibition (E–Inc).” Center: The dog in a tub, tongue out, labeled “E,” connected to “E–S” (enzyme–substrate). Top-right: The dog holding a yellow tennis ball, labeled “Competitive inhibition (E–Ic).” Bottom-center: The dog chewing a blue ball, labeled “Substrate binding.” Arrows and labels show the relationships between each form of the enzyme.

Composite image demonstrating “good” versus “bad” enzyme–substrate binding with the same black dog: Left: The dog with a blue ball in its mouth, labeled “E–Sᵍ” (“bad” binding mode). Center-left: The dog in a tub with tongue out, labeled “E.” Center-right: The dog holding a blue ball in a more controlled way, labeled “E–S” (“good” binding mode). Far right: The dog beside shredded toy pieces, labeled “E + P” (product formation). Text labels and arrows illustrate the transition from enzyme–substrate complexes to products.

It's important to communicate to the public the importance of basic science. Coco is happy to help explain drug binding mechanisms and enzyme kinetics basics:
#scicomm

Are the Trump team’s actions affecting your research? How to contact Nature Use this form to share information with Nature’s news team, or to make suggestions for future coverage.

Use this form to tell us how the new US administration is affecting your research, or suggest future coverage

https://go.nature.com/42SyoUu

a fully grown dalmatian is leaning on a blanket on a couch. he’s smiling with his tongue hanging out a little bit. he has two heart-shaped dots on his face, one on each eye, making him the dog version of the heart eyes emoji.

This is Charlie. He has literal heart-eyes. 14/10 would be an honor to pet (IG: charlie.the.dalmatian)

Anti-Racism Racism Allyship Bias DEI Diversity Diverse Confirmation Bias Equity Equitableness Feminism Gender Gender Identity Inclusion Inclusive All-Inclusive Inclusivity Injustice Intersectionality Prejudice Privilege Racial Identity Sexuality Stereotypes Pronouns Transgender Equality

2. A memo distributed by NSA leadership to its staff says that on February 10, all NSA websites and internal network pages that contain banned words will be deleted.

This is the list of 27 banned words distributed to NSA staff:

a slightly damp golden retriever puppy leaps toward the camera with his front paws right at the bottom of the frame. his ears are flapping out away from his head a bit, and he has the sweetest look in his eyes. his tiny razor-sharp teeth are pristine, and his tongue is a little wrinkled like it doesn’t fully fit in his face yet.

This is Drake. He is very happy to see you. Saw you about five minutes ago, but is thrilled it's happening again. 12/10

Grappa – a machine learned molecular mechanics force field Simulating large molecular systems over long timescales requires force fields that are both accurate and efficient. In recent years, E(3) equivariant neural networks have lifted the tension between co...

Grappa is out: pubs.rsc.org/en/content/a...

We are looking forward to feedback from and extensions by the community! Try it out for your favorite (bio)molecules - ligands, post-translational modifications, metal-enzymes, DNA, ...

Just had my first experience reviewing a paper which was obviously LLM garbage. If you’re a journal editor who wants to find real peer reviewers in the future, do not ask us to review things which are clearly not real after reading two paragraphs. 🧪

Sequence-specific, mechanophore-free mechanochemistry of DNA Nucleic acids, such as DNA, are integral components of biological systems in that they steer many cellular processes and biotechnological applications…

Where does DNA break when pulled? We can tune it! Paper led by Johannes Hahmann, MD simulations by Boris, great collaboration with Herrmann and Goestl labs @ RTWH

www.sciencedirect.com/science/arti...

How to Set your Domain as your Handle The official account for the AT Protocol with a custom domain.   What's a custom domain? A custom domain is a unique name that identifies a website on the internet. For example, Bluesky’s domain is...

Zeigt euren Admins, wie ihr euren Handle und Domain hier verifizieren lasst. Keine Angst, nach Verifizierung verbleibt der aktuelle Handle auch bei euch.

Hallo Bluesky!
Wir sind die Deutsche Forschungsgemeinschaft. #DFG Als Selbstverwaltungsorganisation der #Wissenschaft in Deutschland fördern wir erkenntnisgeleitete #Forschung. Hier erhaltet Ihr Infos u.a. zu Förderangeboten, Ausschreibungen und Anträgen. Wir freuen uns auf den Austausch!

DFG verlässt Plattform X

Da schau an: Die DFG verlässt X!

Again: Gute Argumente in der Wissenschaftspolitik zahlen sich aus. Hartnäckigkeit ebenso. #eXit

@zolke.bsky.social