Massive thanks to everyone involved! Especially, the Bennett group @ndcnoxford.bsky.social and the Newstead team @kavlioxford.bsky.social @oxfordbiochemistry.bsky.social. Big shout out to my co-first author @sigurbjornm.bsky.social!
We've found a new gene linked to chronic pain in humans! The gene SLC45A4 encodes (the long-awaited) neuronal polyamine transporter, which is important for pain signalling in nerves. We hope this discovery might lead to new chronic pain treatments in the future!
www.nature.com/articles/s41...
Our paper on SLC45A4 is out now in @nature.com! The orphan SLC45A4 transporter is a polyamine transporter involved in chronic pain signalling!
📣 NEW: Breakthrough discovery of a genetic link to pain co-led by NDCN's Prof David Bennett and Prof Simon Newstead @oxfordbiochemistry.bsky.social
The results of the research, published in @nature.com, could lead to a promising new target for the treatment of #chronicpain.