🎊 New drug revolutionising the management of #obesity
✅ New kid on the block
👀 Check out the visual abstract of the #REMODEL trial
#semaglutide
@theisn.org
#ISNWCN
@dilushiwijay.bsky.social @nephroseeker.medsky.social @dramiliflores.bsky.social

Glad to have discussed the case for #ECNeph. Thank you all for your support and guidance! @myadla.bsky.social @dramiliflores.bsky.social @dilushiwijay.bsky.social @theisn.org 🙌

🚨 Cardiorenal Syndrome (CRS): A Deadly Duo 🚨
Did you know the heart & kidneys are so intertwined that dysfunction in one can wreak havoc on the other?
Let's dive into CRS today.
A lucid read for every nephrology & cardiology fellow 🫀🩺
#MedTwitter
#ISNTweetorial

Hi this is Dilushi, joining a bit late! And lurking tonight #ECNeph

“Now we must… turn words into actions: We need steady investment, teamwork across sectors, and real action in every corner of the globe. This isn’t just about better kidney care -it’s .. making healthcare fairer & more accessible for everyone, especially in LMICs that need it most.” 👏🎉

🌍 History made! For the first time, kidney care is on the global health agenda. #WHA78 adopted a landmark resolution recognizing kidney health in the fight against #NCDs.

👏 Thanks to Guatemala and the global kidney community for making this possible!

#KidneyHealthMatters

Finerenone Finally Finishing off Spironolactone? — NephJC A commentary putting the recent finerenone and spironolactone trials in perspective

longer discussion including MRAs and ASIs here www.nephjc.com/news/2024/10...

#WorldHypertensionDay

The KDIGO 2021 BP Guidelines — NephJC KDIGO; BP; blood pressure; guidelines; kidney; kidney disease; CKD; transplant; bp measurement; AOBP; ABPM; ACE inhibitors

BP Targets:

the @kdigo.org www.nephjc.com/news/kdigo-bp

The ESPRIT trial discussion www.nephjc.com/news/esprit

The BPROAD discussion
www.nephjc.com/news/bproad

#WorldHypertensionDay

#120ForAll

Global and national high blood pressure burden and control High blood pressure is a leading modifiable cause of premature death and one of WHO's global targets for the prevention of non-communicable diseases. Monitoring high blood pressure globally while unde...

The @thelancet.com review on global BP control
www.thelancet.com/journals/lan...

Worsening BP control in Canada www.sciencedirect.com/science/arti...

Improving BP control in US from @amjhypertension.bsky.social academic.oup.com/ajh/article/...

#Hypertension #WorldHypertensionDay

The Na-K Exchange Saves Lives — NephJC This week, we will discuss the SSASS trial. in which a simple switch of table salt with a K-enriched salt works miracles. Is it about the sodium or the potassium?

K issues
#NephJC www.nephjc.com/news/salt-su...
Podcast www.nephjc.com/freelyfilter...

K switch mechanism
pubmed.ncbi.nlm.nih.gov/38081406/ in @ajkd.bsky.social

pubmed.ncbi.nlm.nih.gov/37772757/ from @amjhypertension.bsky.social

journals.physiology.org/doi/full/10....

#WorldHypertensionDay

Effects of Sacubitril/Valsartan Versus Irbesartan in Patients With Chronic Kidney Disease - PubMed URL: http://www.isrctn.com . Unique identifier: ISRCTN11958993.

The ARNI data in CKD here pubmed.ncbi.nlm.nih.gov/30002098/

#WorldHypertensionDay

#23 𝗦𝗔𝗩𝗘 𝗧𝗛𝗘 𝗗𝗔𝗧𝗘 for next Space #WorldHypertensionDay: "Hypertension and the Kidneys."

@edgarvlermamd.bsky.social @hswapnil.medsky.social @myadla.bsky.social @dilushiwijay.bsky.social @ferarceamare.bsky.social
🗓️ May 22
🕑 3:00 pm CEST
⏰ Set your alarm here: twitter.com/i/spaces/1jM...

Great meeting with the @ISNEducation social media team; lots of exciting projects on the horizon!
We're looking forward to what’s coming next, so stay tuned!

Guatemala's resolution on kidney health: a historic opportunity Although much remains to be done, tremendous progress has been made on the prevention and control of chronic non-communicable diseases (NCDs), with slow but steady health gains achieved for millions o...

Guatemala's resolution on kidney health: a historic opportunity - The Lancet www.thelancet.com/journals/lan...
Tonelli et al: "We call on all 193 UN Member States to bring about positive change by voting to adopt Guatemala's resolution on kidney health at the 78th WHA in May, 2025."

Vulture as Reviewer #2, about to drop piano on man thirsty in desert, about to drink water.

#AcademicSky #AcademicPublishing #AcademicChatter

Thanks, milagros #NephJC

Another great question about tranexaminc acid in urological bleeding.. we usually use it for post-biopsy bleeds. Does anyone have reservations about this? #NephJC

📅 Get ready for the next #NephJC on May 29 🧠💊
We’ll dive into:
Lorundrostat for Uncontrolled Hypertension — efficacy, safety, and what it means for the future of BP management.
⏰ #NephSky #MedSKy

@nejm.org www.nejm.org/doi/ful...

Same with us, but sometimes due to lack of availability switch to 18G for native. There are always concerns about adequacy when this happens #NephJC

Deamino-8-D-arginine vasopressin shortens the bleeding time in uremia - PubMed In a randomized double-blind cross-over trial we gave either 1-deamino-8-D-arginine vasopressin or placebo to 12 patients with uremia, hemorrhagic tendencies, and prolonged bleeding times. After vasop...

#NephJC One of my fave all time papers in this topic is a proof-of-concept DDAVP in CKD: reduces bleeding time consistently @nejm.org pubmed.ncbi.nlm.nih.gov/6401193/

Don´t forget to advocate the resolution led by Guatemala on #WHA78:
🌍 Chronic kidney disease affects over 850M
We must shift from silent neglect to strategic action.
Awareness, prevention, and equity in care are our next steps.
#NephJC @theisn.org #NephSky #MedSky

www.thelancet.com/jo...

a man stands in front of a whiteboard with the word wait written on it ALT: a man stands in front of a whiteboard with the word wait written on it

One the one hand, low risk intervention. On the other hand, still unclear benefits.
We doctors like to feel like we are doing something to prevent bad outcomes…but “don’t just do something, sit there” is also appropriate in many patients #NephJC

Not routine, but may be for selected patients #NephJC

🩸Desmopressin appears safe, any serious risks?
Hyponatremia, headaches, hemoglobin drop 🧪
We need stronger data on who, when, and how much.
#NephJC

Not exactly the topic, but what about treatment of post biopst bleeds? Is it a single dose of DDAVP, or would your redone? If so do you have a suggested protocol- timing, Na check? #NephJC

Defective platelet aggregation in uremia is transiently worsened by hemodialysis - PubMed Bleeding is a prominent feature of uremia and remains a significant cause of morbidity in hemodialysis (HD)-dependent patients. To measure the impact of the HD procedure, we performed a prospective cr...

#NephJC

pubmed.ncbi.nlm.nih.gov/7702050/

I do that too. If severe AKI or CKD stage 5 knocking the uremia door I lower my HD threshold. That’s an area where data are needed though #NephJC

#NephJC

Hb drop with desmopressin? Is that due to water retention? Could cause some confusion if that is the case? #NephJC

Whats your practice with regards to dilaysis pre-procedure to prevent bleeding? Are you aware of any evidence to support it? #NephJC