Results like these underscore how shortsighted the current stance of the US Health and Human Services Dept against mRNA vaccine technology is…

Pancreatic cancer mRNA vaccine shows lasting results in an early trial Scientists caution that more research is needed, but nearly all of the patients who responded to the personalized vaccine are still alive six years later.

"Pancreatic cancer mRNA vaccine shows lasting results in an early trial: Scientists caution that more research is needed, but nearly all of the patients who responded to the personalized vaccine are still alive six years later."

My wife asked me to repost this in case some folks missed it.

She is de-stashing her treasure hoard of yarn. There's a lot of it. It's kinda taken over the house. I'm in the attic of the garage right now. Help?

www.etsy.com/shop/Destash...

The excitement I get when I read mind-blowing discoveries like these is why I got into science to begin with

Lovin’ that science can buoy me up still despite the world turning into a dumpster fire all around us (which gets me down every day)

This is WILD
(& microbes rock 🎸)
“These findings […] revealing a protein-templated mechanism for sequence-specific DNA synthesis.”

Take that, central dogma! 🧪

“Protein-templated synthesis of dinucleotide repeat DNA by an antiphage reverse transcriptase”
www.science.org/doi/10.1126/...

It brings me great pleasure to say that @aphrc.bsky.social is hiring
Apply Repost and Share Widely!!
Apply on our website;
aphrc.org/careers/

#IamAPHRC #WeAreAfrica #IkoKazi #IkoKaziKE

We are recruiting 1-2 postdoctoral fellows to investigate the specificity of human anti-influenza virus antibodies, and to determine how these antibodies impact global antigenic drift of influenza viruses.

Join our lab at Penn in Philly. Reach out if you are interested in applying! Please repost!

📣 New paper out in @plosbiology.org

What drives global patterns of species richness? 🌍 Using a unified framework across 129 tetrapod clades 🐸🦎🐦🐘, we find:

👉 Productivity-driven equilibrium dynamics largely explain biodiversity patterns ⚖️🌱

doi.org/10.1371/jour...

#Macroecology #Biogeography

A basket of decorated Easter eggs and a vase of yellow and white daffodils

Happy Easter everyone!
Feliz Pascua

A basket of decorated Easter eggs and a vase of yellow and white daffodils

Happy Easter everyone!
Feliz Pascua

Exactly this! The same way institutions care about ethical human and animal research, and (hopefully) biosafety, they need to care about the integrity of the rest of the experiments.

And certainly not try to sweep the issues under the rug if they arise

N*M210 inhibits SG/RLB formation by sequestering dsRNA. HeLa cells expressing N*M210-FLAG (blue) were transfected with poly (I:C) (pink) and SG/RLB formation was measured using TIAR (yellow). This experiment was conducted and imaged by Rory P Mulloy, who agrees to publish this image under a CC-BY licence.

#SARSCoV2 has optimized its replication fitness in the human host. @rorymulloy.bsky.social @corcoranlab.bsky.social &co show that a #nucleocapsid gene mutation enhances production of a truncated protein that boosts viral fitness by suppressing #antiviral responses @plosbiology.org 🧪 plos.io/3PIZMjr

Cover of this week’s Nature featuring papers on reproducibility issues in social and behavioural sciences

More self-reflection in research can lead to better science - as shown by a package of social & behavioural sciences papers that shows how collaborating can further the cause of reproducible, replicable & robust findings
@nature.com 🧪 #SCORE
@briannosek.bsky.social
www.nature.com/articles/d41...

The Orange Cat Brain Atlas is here. 🧠🐈

Today, we published the first comprehensive cellular map of the orange cat brain. The new atlas reveals a single, specialized neuron responsible for behaviors like staring at walls, knocking objects off tables, and the 3am "zoomies."

A relaxed grey cat

Having a teenage cat is stressful - Gandalf has spent 5hrs outside this afternoon (he usually does this only at night) and nerves were high here, but he is just peachy 🤣🐈‍⬛

Redefining Publishing: PLOS, supported by the Gordon and Betty Moore Foundation & Robert Wood Johnson Foundation, is launching an important new initiative PLOS believes in a better future where science is open to all, for all. We are redefining publishing by demonstrating that new solutions are feasible and deliver tangible benefits for the entire resea...

I believe that PLOS has looked (is looking?) into this, but there may be quite a crowded landscape, and added to the fact that a significant amount of resources and time are going to plos.org/redefining-p... may limit developments in this regard

In our new pre-print, we established massive single-cell RNA-sequencing for diatoms to investigate key cell fate transitions. Notably, we discovered that the diploid-to-haploid transition is regulated by Myb TFs, a process that is actively ongoing across the Global Ocean! 🌊

Bacterial 2′,3′-cGAMP activates a SAVED effector to form membrane-disrupting filaments and restrict phage replication Tak et al. discover that bacteria use 2′,3′-cGAMP, the same signaling molecule employed by mammalian cGAS-STING, for phage defense. In response to phage, 2′,3′-cGAMP activates filament formation of Ca...

Happy to share the final version of my postdoc work on bacterial CBASS immunity with @aaronwhiteley.bsky.social published in @cp-cellhostmicrobe.bsky.social

www.cell.com/cell-host-mi...

Really neat piece of work in @plosbiology.org, inferring the hidden layer of "fitnotypes" that link genotypes to fitness, and finding surprisingly low dimensionality. From @oliviamghosh.bsky.social @grantkinsler.bsky.social @benjaminhgood.bsky.social & @petrovadmitri.bsky.social

So happy to see this finally published in @plosbiology.org!

This is the first chapter of @julielebris.bsky.social PhD thesis demonstrating how capsules are exchanged by plug-and-play dynamics
w/ @epcrocha.bsky.social
#microsky @klebclub.bsky.social
Link below-
Check out her 🧵 for more details!

En estas dunas de la Albufera de València se ejecutó un proyecto de eliminación de flora invasora en 2025. Este Carpobrotus edulis es un rebrote de una de las plantas eliminadas. Es esencial revisar periódicamente las zonas de erradicación d sp invasoras para evitar su reinvasión a corto plazo. #EEI

Firma la petición Eureka! Zientzia museoa ez ITXI– Euskadi necesita su museo de la ciencia

Petición para que no cierren el museo de ciencia de San Sebastián - una buena causa que apoyar

Petition to avoid the closure of San Sebastian’s science museum - a worthy cause if you’re looking for something to support

🧪

www.change.org/p/eureka-zie...

Excited to be heading to Copenhagen for #ELCC26 @myesmo.bsky.social, on behalf of @plosmedicine.org! If you’re attending and would like to chat about your latest research or explore publishing opportunities with PLOS, let’s connect. Feel free to say hello at the conference or reach out on BlueSky.

Conference attendance! If you're heading to the European Lung Cancer Congress in Copenhagen, keep an eye out for our Senior Editor Alex Tosun! 🧪 #ELCC26
@atosun.bsky.social

Apply now! The 2026 call for the EMBO Young Investigator Programme is now open with a deadline of 1 April 12:00 midday CEST. 🧪

More info here:
www.embo.org/funding/fellowships-gran...
#LifeSciences #research #funding

A los votantes de PP, Vox y Junts también les afectan las subidas abusivas del alquiler.

No podemos permitir que los millones de euros de ayudas acaben en el mercado especulativo de la vivienda.

Vamos a empujar hasta el final para prorrogar los contratos.

The New Yorker cover from a 2016 issue showing a British business man in classic attire walking off a cliff

Throwback @newyorker.com cover of 2016 seen yesterday at the V&A museum in London.

It was clear at the time already, but how right they were…

Fellows The European Academy of Microbiology (EAM) proudly brings together a distinguished community of leading scientists whose contributions have shaped and advanced the field of microbiology. Below, you wi...

Congratulation to the newly elected members of the European Academy of Microbiology!

Lots of friends among the lot, which includes @plosbiology.org academic editors @katholt.bsky.social @sophiemartinlab.bsky.social and Arjan de Visser

🎉🧪#Microsky #Virosky

fems-microbiology.org/european-aca...

$2.45 billion NIH grant cuts and ~2300 terminated active research grants were DOGE'd in early 2025
Who were most affected?
www.pnas.org/doi/full/10....
Early career and women researchers

Sublinear and linear scaling coexist in bipartite graphs

Real ecological networks are constrained by the presence of specialists

Coextinction risk is driven by host extinction risk - but especially high for specialists

‼️ New preprint: By solving a paradox in graph theory, we show that specialist symbionts constrain ecosystem structure, drive biodiversity, and face high extinction risk. With @jbyoder.org and @ctrlalttim.com:

🎉 Specialists drive biodiversity scaling in symbiotic relationships