Here it is:
Atera: ยซย High throughput. Whole transcriptome. Single cell sensitivity.ย ยป
pages.10xgenomics.com/wbr-2026-02-...
Thoughts?
Posts by Silas Maniatis
A picture of the Manhattan skyline silhouetted against the sunset, viewed from Brooklyn
Brooklyn golden hour still undefeated
Holy New York.
Black graphic with text "KNOW YOUR PROTEST RIGHTS You donโt need a permit to protest in response to breaking news and you donโt need a permit to march in the streets or along sidewalks, as long as youโre not obstructing traffic or access to buildings. When you are lawfully present in any public space, you have the right to photograph anything in plain view, including federal buildings and the police. If you believe your rights have been violated, when you can, write down everything you remember, get contact information for witnesses, and take photographs of any injuries. If you get stopped by the police, ask if youโre free to go. If they say yes, calmly walk away. If you get arrested, you have a right to ask why. Otherwise, say you wish to remain silent and ask for a lawyer immediately. Donโt sign, say or agree to anything without a lawyer present. If you get stopped by a member of the military or any law enforcement office at a protest, you have the right to remain silent or to tell them that youโll only answer questions in the presence of an attorney โ no matter your citizenship or immigration status."
If you're taking to the streets for No Kings protests today, know your rights.
Find your nearest event at nokings.org/?SQF_SOURCE=aclu
When using this link, Indivisible will know you came from us; their privacy policy applies.
Todayโs official soundtrack:
youtu.be/BlIREcAu0PI?...
The @mind-western.bsky.social #fluorescencefriday entry focus on the hippocampus of an aggressive AD model Appnl-g-f with IBA1 (yellow) and abeta (magenta). thanks to @shahrzadbahrampour.bsky.social @nadiahaghbinphd.bsky.social and @kesummers.bsky.social
Despite the obvious superiority of fresh-frozen material for genomics, many samples are still stored in FFPE and remain challenging to characterize with Whole-genome sequencing. But here comes our solution:
NYT headline: First 6 days of Iran War Cost US $11.3 billion, Pentagon says
The ERC budget for 2026 is 2.7 billion euros ๐งช
Excited to share this preprint that describes my latest work on using GPUs to accelerate processing of RNA-seq data.
The title says it all: "RNA-seq analysis in seconds using GPUs" now on biorxiv www.biorxiv.org/content/10.6... and github github.com/pachterlab/k...
Figure 1 shows they key result
Khedโฆ this fahkin guy bettah neva show his face neah Hahvahd again. Theyahโs gonna be like 20 doahds named Kennedy come outah Paddyโs Lunch ready foah him. Gonna be fahkin mint seein him have to drink a box oโ Joe to him self when they done with him. www.bostonglobe.com/2026/03/04/n...
$300 Million in jet planes lost to a fuckup.
Thatโs 83 five year NIH R01 grants burned in minutes due to error, aka poor execution of this unnecessary war which serves only to make the world more dangerous.
As a federally funded researcher, every time I see the now customary start of war videos showing a BGM-109 TLAM launching from the bow magazine of a U.S. DDG at $2.5M a pop (FY 2023), I see a fully funded 5 year flagship NIH R01 biomedical research grant zooming off into oblivion.
#fluorescencefriday mapping the relationship between amyloid (green), microglia (magenta) and blood vessels (orange) in and aggressive model of AD. from @arashsalah.bsky.social @nadiahaghbinphd.bsky.social @shahrzadbahrampour.bsky.social @mind-western.bsky.social
On February 19, 1942, President Franklin D. Roosevelt signed E.O. 9066, authorizing the forced relocation & incarceration of more than 125,000 Japanese Americans, solely because of their heritage.
Nothing says โIโm a tough guy with the biggest baddest military in the world, and no one can mess with me if WWIII happens!โ Like scrubbing all mention of biodefense or pandemic preparedness does.
www.nature.com/articles/d41...
A young Fred Korematsu
A photo of Fred Korematsu in his later years
"It may take time to prove you're right, but you have to stick to it."
- Fred Korematsu
Jailed for refusing to abide by FDR's Exec Order 9066, he took his case against internment all the way to the Supreme Court - and lost. Remember him on Korematsu Day, January 30th. 1/
*Homan.. sorry for the typo, but Iโm pretty sure you know which recipient of $50k in tax payer cash, delivered in a shopping bag, I am referring too. You know, the one who was never senate confirmed, and thus should not be in any chain of command in MN.
Just called both of my senators @schumer.senate.gov and @kirstengillibrand.bsky.social to let them know that appropriations for DHS are not compatible with a free society and that personnel shuffles do not matter. Even if my federal funding ends as a result, DHS must go and Holman Bondi et al too
A snowy bus stop outside the NIH. Snow on the ground and sleeting down, everything is grey and white.
Fighting through snow so I can do my science. Animal care staff, building staff, clinical staff, nurses, doctors, veterinarians all work through these weather conditions to make the NIH run.
This line graph illustrates the percentage change in agency staff levels from the previous year for nine major U.S. federal scientific and health organizations between the fiscal years 2016 and 2025. The agencies tracked include the CDC, Department of Energy, EPA, FDA, NASA, NIH, NIST, NOAA, and NSF. For the majority of the timeline between 2016 and 2023, the agencies show relatively stable fluctuations, generally staying within a range of +5% to -5% change per year. However, there is a dramatic and uniform plummet starting in the 2024โ25 period. Every agency depicted shows a sharp downward trajectory, with staffing losses ranging from approximately -15% to over -25%. The Environmental Protection Agency (EPA) shows the most significant decline, dropping to roughly -26%, while the National Institute of Standards and Technology (NIST) shows the least severe but still substantial drop at approximately -15%.
This is the most astonishing graph of what the Trump regime has done to US science. They have destroyed the federal science workforce across the board. The negative impacts on Americans will be felt for generations, and the US might never be the same again.
www.nature.com/immersive/d4...
Seems like voluntarily installing a secret police surveillance node at oneโs own expense might be an action that oneโs neighbors find upsetting. Would be weird and totally unrelated if all of a sudden lots of these went missing, or had sensors damaged with lasers etc
techcrunch.com/2025/10/16/a...
A teenage boy with dark hair and a black and gold football jersey holds his helmet, standing on the side line of a green football field
Iโm one of the ProPublica reporters who has been documenting the aggressive tactics federal agents are using against immigrants & U.S. citizens
All eyes are on Minnesota right now, but I want to tell you about Arnoldo Bazan, a 16-YO citizen in Houston who was choked by immigration agents in October
3 papers in Cell @cellpress.bsky.social today exploring the mechanistic connection between Epstein-Barr virus and multiple sclerosis #MultipleSclerosis
cell.com/cell/fulltex...
cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
TDP43 dysfunction in ALS leads to transposon mayhem in the transcriptome. Nice work from @nygenome.org โs ALS consortium, lead by Hemali Phatnani, and @nyulangone.bsky.social โs @karthiknatarajan.bsky.social & @mollygale.bsky.social. Nice work guys!
www.biorxiv.org/content/10.6...
Figure illustrating some content of the Python course for biology students at UniBonn
โAnalysis of Biological Data with Pythonโ started today for biology bachelor students ๐งฌ๐
Want to learn Python for data analysis?
Slides are freely available:
github.com/bpucker/teac...
#Python #DataAnalysis #Biology #OpenScience #BigData #Bioinformatics #DataScience @puckerlab.bsky.social
New York City turned OUT.
@handsoffnyc.bsky.social โโค๏ธ
Never forget. ๐บ๐ธ
Zohran just went out and fixed the Williamsburg Bridge bike entrance. Just did it. No faffing, no nonsense. Bam. Fixed.
A comprehensive spatial splicing analysis in the brain under normal and neoplastic conditions @natbiotech.nature.com @raulrabadan.bsky.social @columbiauniversity.bsky.social @davidaknowles.bsky.social @nygenome.org
www.nature.com/articles/s41...