#better #biostatistics #better #science

▫️ Predefine few credible subgroups
▫️ Use interaction tests
▫️ Correct for multiplicity
▫️ Treat positive findings as provisional until replicated. That framework is meant to separate real effect modification from chance findings created by subgroup fishing.

#better #study #design #better #decisions

Involve statisticians during study design rather than after data collection ‼️
Design decisions are irreversible, Design saves time & money. Increased publication success, Statistical rigour tied to funding and grants #better #studydesign #better #science

Empowering Biotech Innovation Through Biostatistical Mentoring | Natalie Rodrigue ‼️ Mentoring in Biostatistics for Biotechs & Medtechs 🚩 Help Bridge Knowledge Gaps Most biotech startups possess deep scientific expertise but limited biostatistical experience, creating vulnerab...

www.linkedin.com/posts/natali...
mentoring

statistical.solutions/the-primary-...

Clinical trial findings are often simplified into a binary conclusion, focusing on a P value of less than 0.05 for a treatment difference. However, a more nuanced interpretation requires examining the total evidence.

#decision #stats #clinical #trials

#statistics #stats Reading QQ plots is not easy at first. I can relate! But don't give up just because it's hard. Everything is hard until you know it and suddenly it becomes your daily tool. Practising and mastering QQ plots (and CDF, BTW) isn't a waste of time! Below I show a few examples.

Statistical Reporting Needs to Convey More Details for Clarity

Please visit it to read the entire story.
lnkd.in/eMUq8Hti

❗ We have recently created a new blog on our Statistical Solutions website: The Good Science: lnkd.in/estgx2yh.

#reporting #statistical #methods #reproducibility

Bird at sunset, Spain, 2022
Copyright: Natalie Rodrigue
To see my portfolio: 500px.com/p/natalierod...
#photography #nature #sunset

When is the t-test appropriate?

▶️ In short, the t-test is needed when P values are required and there are no nuisance variables to control for nor covariates to adjust for.

In practice, having no nuisance variables/covariates to adjust for is relatively rare situation.

#stats #ttest #DoE

Here is a cheat sheet that you might find useful to create table 1 found in biomedical research papers in R.

lnkd.in/eVVkCCeB

#Rstats #stats #table1

Teardrop. Shot in December 2022.
Copyright : Natalie Rodrigue
#photography #macro #nature #abstract #shape

Stained glass windows in Aigues-Mortes. Shot in 2023.
Copyright Natalie Rodrigue
#photography #abstract #art #geometry #shape

Key Biostatistics for MLS is available as distance learning. Become more proficient when discussing with KOLs.
Master key concepts the medical literature #biostatistics #MLS #distancelearning #online #training contact me to learn to find out more.
statistical.solutions

lnkd.in/eNgRqZBg

Abstract photography black and white cube

#photography #abstract

Following the demand of several bioinformaticians, we developed a training program: Statistical Analysis of Metagenomics Data in R.

Metagenomics data possess specific features that call for adapted statistical methods.
#metagenomics #data #analysis #training #R

Interpreting & reporting clinical trials (CTs) with results of borderline significance
▶️ What's the problem?
▶️ Using confidence intervals
▶️ Inconsistency in language in reports
▶️ Recommendations
This paper is NOT only relevant to CTs, its scope is much broader.
#significance #statistics #science

Corporate Training in Biostatistics

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Contact Natalie Rodrigue to learn more and set up your training programme for 2025

#training #biostatistics #better #science

🩵 Statistics notes: Absence of evidence is not evidence of absence

A great classic! A must read paper for research scientists, reviewers, MLSs/writers and readers in general.

www.bmj.com/content/311/...

#statistics #science #inference #reproducibility

Who is in this study, anyway? Guidelines for a useful Table 1 Epidemiologic and clinical research papers often describe the study sample in the first table. If well-executed, this “Table 1” can illuminate potential threats to internal and external validity. However, little guidance exists on best practices for designing a Table 1, especially for complex study designs and analyses. We aimed to summarize and extend the literature related to reporting descriptive statistics.

🗃️ Who is in this study, anyway?

💡 Table 1 & Usefulness
In biomedical research papers, Table 1 shows demo & baseline variables of the study population. Used for assessment of whether the groups differ wrt characteristics.

www.jclinepi.com/article/S089...

#table1 #guidelines #reproducibility