What’s on the horizon in Parkinson’s disease research? In honor of #ParkinsonsAwarenessMonth, VAI’s Dr. Darren Moore highlights five areas to watch for breakthroughs in the coming years.
Read more: www.vai.org/article/5-ar...
Can a chronic stomach infection influence #Parkinsons disease risk? Recent findings by VAI’s @mxhend.bsky.social and colleagues reveal how infection by the H. pylori bacterium may influence the risk and progression of Parkinson’s.
www.vai.org/article/can-...
❗🧠 New review in IEEE RBME
How network math models are reshaping how we think about neurodegenerative disease, from brain dynamics to disease progression
"Network models of neurodegeneration: bridging neuronal dynamics and disease progression"
ieeexplore.ieee.org/document/113...
Exciting study of Alzheimer's plasma biomarkers in a community sample. The finding I was most surprised by was this plot of biomarker prevelance by education. We know education reduces incidence of AD, but this shows it also prevents biological markers of AD! www.nature.com/articles/s41...
Great job, Noah!
A study by @mxhend.bsky.social and collaborators found that an unstructured layer surrounding the Alzheimer’s-related protein tau plays a critical role in recruiting other proteins to misfold in Alzheimer’s progression. The findings were published in @natcomms.nature.com. www.vai.org/article/not-...
Another graduate student defended! Congratulations, Dr. Goralski!
Sjors Scheres
Excellent opportunity for a postdoc to join @sjorsscheres.bsky.social in the LMB’s Structural Studies Division to work on #cryoEM structure determination of amyloid filaments in a lively, multi-disciplinary group.
Read more: www.nature.com/naturecareer...
Closes 03 AUG
#PostdocJobs #ScienceJobs
Excited to have several new lab members join us this year!
We are thrilled to announce that renowned physician-scientist J. Timothy Greenamyre, M.D., Ph.D., of University of Pittsburgh, will be the recipient of the 2025 Jay Van Andel Award for Outstanding Achievement in Parkinson’s Disease Research!
Congratulations to grad student Ben for passing his qualifying exam! Now he gets to do all the exciting research he has proposed!
Great collaboration with @sjorsscheres.bsky.social led by graduate student @alysa-kasen.bsky.social! It turns out core filament structure and fuzzy coat PTMs contribute to tau seeding.
Another first place poster prize for graduate student @alysa-kasen.bsky.social for her work on tau pathology seeding! She is finishing up this summer and looking for a postdoc if anyone needs an excellent scientist!
Pharmaceutical company Roche announce that their Phase IIb PADOVA study of the alpha synuclein targeting antibody Prasinezumab just missed its primary endpoint (p=0.0657), but their data suggests possible clinical benefit in early-stage #Parkinsons
www.roche.com/media/releas...
Henderson Lab winter party 2024! Happy holidays everyone!
