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Posts by Thomas Deffieux

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New paper in Imaging Neuroscience by Samuel Le Meur-Diebolt, Thomas Deffieux, et al:

Robust functional ultrasound imaging in the awake and behaving brain: A systematic framework for motion artifact removal

doi.org/10.1162/IMAG...

1 week ago 5 3 0 1

⚠️ Postdoc Opportunity in System Neuroscience at the Paris Brain Institute ⚠️

Feel passionate about neuroscience and sleep 🧠? Want to learn cutting-edge techniques 🔬 to answer exciting basic science questions? Want to work in a multidisciplinary environment at the heart of Paris 🏨?

Come join us !

1 week ago 14 13 1 0
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1/8. New preprint!

Using fUSi in head-fixed mice🐭, we found that arousal events trigger a brain-wide wave of activity 🌊🧠.

Surprisingly, this pattern was preserved during opto manipulations of the locus coeruleus, pointing to a minor role for noradrenergic tone.

www.biorxiv.org/content/10.6...

1 month ago 34 12 2 2
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🚀 We are hiring: a PhD position is available in my lab (gozzilab.it) at @iitalk.bsky.social, Italy. Project: large-scale brain network mapping in behaving mice using functional ultrasound imaging (FUSI).
📅 Deadline: March 31
🔗 tinyurl.com/4jtetxa9
Reshares appreciated 😊

1 month ago 13 15 0 1
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fUSI-BIDS extension proposal v0.0.12 BIDS Extension Proposal 40 (BEP040): fUSI-BIDS version 0.0.12.dev Available under the CC-BY 4.0 International license. Extension moderators/leads: Jean-Charles Mariani <jean-charles.mariani@cri-paris...

Next #fUSI - #BIDS meeting is coming up! 🧠

📅 March 19, 5PM CET
🎯 Solving remaining spec remarks & moving toward official maintenance.

Newcomers welcome! 🚀 Planning to BIDSify your data? Join us, we’re here to answer your questions.

Details on the GDoc: docs.google.com/document/d/1...

1 month ago 4 2 0 0

wow, congrats. amazing job and results !
Glad to see fUSI passing the fMRI acid test at so many different levels and pushed forward by fMRI experts. This is both highly impressive work and foundational for the field!

2 months ago 1 0 1 0
Structural and dynamic embedding of the mouse functional connectome revealed by functional ultrasound imaging (fUSI) Functional ultrasound imaging (fUSI) is an emerging hemodynamic neuroimaging modality whose potential for connectome-scale network mapping remains largely untested. Here, we establish a non-invasive t...

If you’d like to play with these data or run your own analyses, all datasets (fUSI + fMRI) and the full analysis code are openly available here
zenodo.org/records/1848... 🚀
13/n

2 months ago 2 2 1 0
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𝗞𝗶𝗰𝗸𝗶𝗻𝗴 𝗼𝗳𝗳 𝟮𝟬𝟮𝟲 𝘄𝗶𝘁𝗵 𝗮 𝗻𝗲𝘄 𝗽𝘂𝗯𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻 𝗶𝗻 𝗖𝗲𝗹𝗹 𝗥𝗲𝗽𝗼𝗿𝘁𝘀
@felipecybis.bsky.social, postdoct in our lab, is the first author of the study "A vascular code for speed in the spatial navigation system", now published in Cell Reports: doi.org/10.1016/j.celrep.2025.116791

#Ultrasound #fUS #Research

3 months ago 7 6 0 0
Processing pipeline of HAM-SVD algorithm

Processing pipeline of HAM-SVD algorithm

🚨 𝗡𝗲𝘄 𝗽𝗮𝗽𝗲𝗿 𝗮𝗹𝗲𝗿𝘁: 𝗵𝗮𝗿𝗺𝗼𝗻𝗶𝗰-𝗯𝗮𝘀𝗲𝗱 𝘀𝗶𝗴𝗻𝗮𝗹 𝘀𝗲𝗽𝗮𝗿𝗮𝘁𝗶𝗼𝗻 𝗳𝗼𝗿 𝘂𝗹𝘁𝗿𝗮𝗳𝗮𝘀𝘁 𝘂𝗹𝘁𝗿𝗮𝘀𝗼𝘂𝗻𝗱 𝗺𝗼𝗹𝗲𝗰𝘂𝗹𝗮𝗿 𝗶𝗺𝗮𝗴𝗶𝗻𝗴
“Exploiting harmonic signature of gas vesicles in amplitude-modulated singular value decomposition for ultrafast ultrasound molecular imaging” a paper led by Ge Zhang & @mickaeltanter.bsky.social

2 months ago 3 2 1 0
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eMyosound core technology consist in tracking the speed of shear waves non-invasively for the assessment of cardiac diseases. All the animations are available here: www.sci-vis-com.fr/emyosound #science #medical #imaging 🫀🧪🔬🐡

3 months ago 11 3 0 0
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Just published: non-invasive imaging of pericyte dysfunction in the brain — a major breakthrough for understanding cerebrovascular diseases

#EICPathfinder #Neurovascular #Ultrasound #Neuroscience #fULM #microvasc #PhysMed @mickaeltanter.bsky.social @espciparispsl.bsky.social @inserm.fr

8 months ago 19 8 1 1
fUSbrain #DAYS 2025 | Physics for Medicine Paris

#fUSbrain DAYS 2025 | Last call for registration!
Registrations will close on May 31st! Don't miss your chance to join us on June 19&20 in Paris, for two days dedicated to functional ultrasound neuroimaging!
👉 Check the detailed program and register here www.physicsformedicine.espci.fr/fusbrain2025

11 months ago 3 3 0 0
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🧠 Use functional ultrasound imaging #fUSI to map brain networks mice - Fully funded PhD opportunity at
@cimecunitrento.bsky.social!

Supervisor: Dr. Alessandro Gozzi, Istituto Italiano di Tecnologia

📌 Apply by June 5, 2025
🔗 phd.unitn.it/drcimec

#Neuroscience @gozziale.bsky.social

11 months ago 3 2 0 0
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Opinion | The Science I Would Be Doing if I Weren’t in ICE Detention

"I did not complete a customs declaration for frog embryos (for use in our lab’s research) in my luggage. [...] This would normally result in a warning or a fine. Instead, [...] I was sent to a detention center in Louisiana, where I have spent the past three months."

www.nytimes.com/2025/05/13/o...

11 months ago 18 4 0 1

Congrats David and Baptiste, great work !

1 year ago 1 0 0 0
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[May 24, 2022]

Happy to say our ultrasound paper is now out in Brain Stimulation
doi.org/10.1016/j.br...

We used cultured neurons to dissect mechanisms of ultrasonic neurostimulation.
Most surprising: even an extremely short (4µs) single low-intensity pulse can generate neuronal activity.

1 year ago 3 1 1 0
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[May 6, 2024]

Chaumerliac and Roche, 1949 - An unexpected vasodilator, Mescaline; Experiences made in Dachau in July 1944. - PMID: 18142704

A fitting date to upload this interesting bit of history [its first appearance online I believe]

English translation and original French in thread

1 year ago 1 1 1 0
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#fUSbrain DAYS 2025
Great news, we are extending the deadline for abstract submission to March 21st! Check www.physicsformedicine.espci.fr/fusbrain2025/ for more details.

1 year ago 5 1 0 0

This was a wonderful conference! There was a sense of excitement as talks after talks revealed the incredible European neurotechnology powerhouses that are starting to deliver unprecedented brain health benefits!

1 year ago 1 1 0 0
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Using fUS to investigate the effect of diet on brain health - Iconeus A new study uses the Iconeus One fUS system to show that poor diet in the mouse negatively affects blood flow regulation in the brain, with implications for brain health.

functional Ultrasound imaging provides new insights about the effect of fat diet on the brain and its protection using polyunsaturated acids
Collaboration with Hirac Gurden team iconeus.com/using-fus-to...

1 year ago 10 3 1 0

Illustration done for the first publication of my colleague Nicolas Zucker. He managed to measure heart and breathing rate by monitoring tissue motion in the brain using ultrasound, what a crazy idea ! #sciart 🐡 #scicomm 🧪 #neuroscience 🧠🫀🫁🤯

1 year ago 37 8 1 0
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Brain computer interface (postdoc/engineer)

🧠 Postdoc Position !
Join us in Paris to work on brain-machine interfaces (BMI) using functional ultrasound (fUS)! We're seeking a postdoc to further develop and validate fUS-based BMI with Caltech and Iconeus.
#Neuroscience #BMI #fUS #Postdoc
www.physicsformedicine.espci.fr/brain-comput...

1 year ago 6 3 0 0
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fUS-BIDS extension proposal v0.0.9 BIDS Extension Proposal 40 (BEP040): fUS-BIDS version 0.0.10 Available under the CC-BY 4.0 International license. Extension moderators/leads: Jean-Charles Mariani <jean-charles.mariani@cri-paris.org>,...

Hey fUSI users. As you were well aware, the next meeting on fUSI-BIDS, our soon to be data sharing standard, is happening next week 12/02 4pm CET. Please join us (details in the doc docs.google.com/document/d/1...) to discuss bidsification, metadata and share your opinion before your data 😉

1 year ago 5 3 0 0
A Neuropixels Opto probe with 3 blue emitters and 3 red emitters lighting up in succession, with corresponding neural activity in different layers of the cortex.

A Neuropixels Opto probe with 3 blue emitters and 3 red emitters lighting up in succession, with corresponding neural activity in different layers of the cortex.

Neuropixels and Optogenetics are delighted to announce the birth of

Neuropixels Opto

Combining high-resolution electrophysiology and optogenetics

Today in bioRxiv

960 sites, 28 emitters, 2 colors

By Lakunina, @karolinazsocha.bsky.social, Ladd, et al

www.biorxiv.org/content/10.1...

(1/2)

1 year ago 325 115 7 12

Happy to share our latest research on tracking tumor response in triple-negative breast cancer using ultrafast doppler ultrasound, paving the way for personalized treatments. Grateful for the amazing collaborative work with Shannon and the Rafat lab! 🩺🔬 #CancerResearch #BreastCancer #Immunotherapy

1 year ago 5 2 0 0
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Exploring Neural Dynamics in the Auditory Telencephalon of Crows using Functional Ultrasound Imaging https://www.biorxiv.org/content/10.1101/2024.11.26.625563v1 Crows, known for advanced cognitive abilities and vocal communication, rely on intricate auditory sy

Exploring Neural Dynamics in the Auditory Telencephalon of Crows using Functional Ultrasound Imaging www.biorxiv.org/content/10.1101/2024.11....

1 year ago 3 2 0 0
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▶️Braincoder, the BMI feedback conference, features outstanding speakers include Edouardo Fernandez (V1 microstimulation), Guillaume Charvet (Clinatec), Mickael Tanter (fUS), and more international speakers!

▶️We are awaiting your registration! braincoder.sciencesconf.org

1 year ago 3 2 0 0
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thanks, quite new over here !

1 year ago 0 0 0 0

Hi Charles, please add me to the bsky ultrasound club !

1 year ago 1 0 1 0

Neuroscience + Ultrasound imaging + Paris = Show your research ! 🧪🔬🧠

1 year ago 9 1 0 0