A Distinctive Inspiratory Noise in IgLON5-Antibody Disease This case series describes a distinctive inspiratory noise observed during sleep in patients with IgLON5-antibody disease.

Heard it before???
It’s not stridor but an inspiratory noise which myself and @dubeydiv observed in patients with #iglon5 #antibodies

ja.ma/3HkZD1y

Models of autoantibody mediated diseases: actively nearing the human gold standard Human autoantibody-mediated diseases associated with a single autoantigenic target provide several valuable opportunities for precision medicine.1 The impl

academic.oup.com/brain/articl...

My editorial on an actively immunised mouse model of NMDAR antibody encephalitis. Please note my scepticism of clinical trials in this field, towards the end!

Apologies
This link should work

pmc.ncbi.nlm.nih.gov/articles/PMC...

Binding of live hippocampal neurons by monoclonal antibodies created from a cerebrospinal fluid plasmablast extracted from an encephalitis patient

Many congratulations to Professor Irani and co-authors for winning the prestigious 2024 PNAS Cozzarelli Prize in Biomedical Science. 👏🧠 The winning paper was a collaboration between NDCN, The Department of Statistics, and the Mayo Clinic in Florida.

Reminder to all interested in #autoimmune #neurology

Please join us
ce.mayo.edu/neurology-and-…

For great weather, faculty talks and networking…..

This will be a small, focused meeting for you to develop your knowledge and skills in #autoimmune #neurology

onlinelibrary.wiley.com/doi/full/10.10…

Here is the first PROM (patient reported outcome measure) for patients with #LGI1 antibody #encephalitis

Hopefully a major inroad to measuring this disease more carefully 👍

We hope this will help patients in routine practice, and in trials

And now our brilliant #autoimmune #nurse Melanie Box

Next up at #WEDA

Dr Beth Rush
Neuropsychologist and Neurorehabilitation @MayoClinic JACKSONVILLE

Next up @kirantha from #columbia discussing infectious encephalitis

#world #encephalitis #day #america 🇺🇸 #WEDA
is today!!
On the Mayo JAX campus
@MayoClinic @MayoClinicNeuro
Kicked off by Philippa Chapman of encephalitis international

In 3 months (and zero days), we have the inaugural @MayoClinic #florida #autoimmune #neurology meeting. 1.5 days of great speakers and 0.5 days to spend on the beautiful Jacksonville beach 🏖️

Please sign up now ✍️

ce.mayo.edu/neurology-an...

In 3 months (and zero days), we have the inaugural @MayoClinic #florida #autoimmune #neurology meeting. 1.5 days of great speakers and 0.5 days to spend on the beautiful Jacksonville beach 🏖️

Please sign up now ✍️

ce.mayo.edu/neurology-an...

We saw a potential over representation of prostate lesions, a new association, and (coincidentally?) is the main extra neural site of CASPR2 expression

We saw that patient rated outcomes appear more descriptive than current physician rated measures (mRS/CASE) 🩺

Immunotherapy‐Resistant Neuropathic Pain and Fatigue Predict Quality‐of‐Life in Contactin‐Associated Protein‐Like 2 Antibody Disease The long-term clinical outcomes and associated prognostic factors in contactin-associated protein-like 2 (CASPR2)-antibody diseases are unknown. A total of 75 participants with CASPR2 antibodies were...

Our new CASPR2 paper is out in Annals Neurology 🤩

Headlines: Patients have neuropathic pain & fatigue as their main long term complaints which determine QoL. 😰

These are NOT immunotherapy responsive. 👩🏾‍⚕️💊

We also report other nuggets in this thread 🧵 ⬇️

onlinelibrary.wiley.com/doi/10.1002/...

Toward curing neurological autoimmune disorders: Biomarkers, immunological mechanisms, and therapeutic targets This article by Segal et al provides a comprehensive overview of immunopathogenic mechanisms of autoimmune neurological disorders, focusing on the interplay between humoral and cellular immunity, rece...

Very pleased to see this online @NeuroCellPress
With colleagues at @MayoClinicNeuro @MayoFL_NeuroRes @MayoClinic Rochester, we summarise state of the art (and some history 😃) in autoimmune neurology…..ENJOY!!

dlvr.it/THL45K