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Posts by Jake Smith

congratulations, Pawel (and team)!! πŸ‘

1 month ago 1 0 1 0
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Our new paper (with @biotay.bsky.social) is out and on the cover story of @currentbiology.bsky.social !!!! Veronika, a Carinthian mountain cow flexibly uses a β€œmulti-purpose tool” to scratch herself. A video and more information will follow in the comments.
www.cell.com/current-biol...

3 months ago 353 124 9 31

CryoET of microbes inside an animal organ? Yes it’s possible! Check out our new preprint showing how we did it! What an amazing collaboration with amazing scientists who made this possible!

4 months ago 123 35 2 4

if you have to do MFA twice in the same "day": go to bed

6 months ago 0 0 0 0
teamtomo.org Modular Python packages the cryo-ET community can depend on.

maybe teamtomo.org needs a blooper reel section @alisterburt.bsky.social? I have quite the impressive back catalogue from the early lift out days...

7 months ago 5 0 1 0
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Tiny Tubes Reveal Clues to the Evolution of Complex Life | Quanta Magazine Scientists have identified tubulin structures in primitive Asgard archea that may have been the precursor of our own cellular skeletons.

Lokiarchaea are tricky to work with in the lab: they grow very slowly, exclusively in an oxygen free environment with the presence of symbiotic bacteria. But with careful nurturing, scientists hope to witness their cell division at work.

7 months ago 40 14 0 2
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repurposing library monitors

#upthearsenal

7 months ago 1 0 0 0

woooooo!πŸŽ‰

8 months ago 1 0 0 0

hot (well, cold) off the press! ❄️

well done @glynnca.bsky.social & @michaelgrange.bsky.social & fabulous co-authors πŸ‘πŸΌ

#teamtomo #cryoET

9 months ago 10 1 0 0
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thanks Jenny!!!🫰🏼

10 months ago 1 0 0 0

Delighted to see our work in press! πŸ™ŒπŸ”¬πŸ§ 

Thanks to @glynnca.bsky.social, @michaelgrange.bsky.social and the rest of the fabulous co-authors for all your contributions.

Excited to see where in tissue structural cell biology goes next πŸ‘€!

#liftlaughlove #teamtomo #whopper

10 months ago 9 3 0 0

Honestly, I don't think there is an inherent difference (willing to be proven otherwise).

My guess is it's largely due to the uptake in post-processing sorcery (denoising, deconvolution etc.)

11 months ago 3 0 1 0

Happy to chat over DM!

11 months ago 1 0 1 0

Congrats, Rasmus! Awesome stuff

11 months ago 2 0 0 0

I am a ride-or-die Hydra fan. The most versatile of the whole bunch!

11 months ago 5 0 1 0
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inspiring and relatable talk from @alisterburt.bsky.social

#ccpem

11 months ago 10 1 3 0

note to self: don't turn out of office replies on

11 months ago 4 0 0 0

Exploring shaped focused ion beams for lamella preparation www.biorxiv.org/content/10.1101/2025.04....

1 year ago 6 3 0 1
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Check out our paper on Xenon milling of HPF samples, now online @naturecomms.bsky.social

rdcu.be/eczIb

1 year ago 10 3 0 1
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Barista: How caffeinated would you like to be?
Me: Yes

1 year ago 2 1 0 1
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Eukaryotes' closest relatives are internally simple syntrophic archaea Eukaryotes are theorized to have originated from an archaeal phylum Promethearchaeota (formerly 'Asgard' archaea)1,2. The first cultured representatives revealed valuable insight3,4 but are distantly ...

Isolated in just 3 years! (previously, 12 years). We obtained two strains from 'Hodarchaeales', proposed to be closest to our archaeal ancestor. Our analysis suggests the ancestor was an anaerobic, syntrophic, peptidotrophic, archaeon with a simple intracellular structure and possible aerotolerance.

1 year ago 99 35 7 3

A great opportunity! (especially to hear @glynnca.bsky.social spread the plasma gospelπŸ™ŒπŸ»)

1 year ago 2 0 1 0

Congrats Charlie & co.! The use of optogenetics for in tissue CLEM here is really elegant.

1 year ago 0 0 0 0

A long read from 2017 but well worth the time for any scientist who both loves their job and and often finds themselves questioning their life decisions. www.danielnettle.org.uk/wp-content/u...

1 year ago 114 45 5 15

We have quite a range of PhD projects this year, covering cryo-EM methods, bacteriology/bioenergetics, and infection/antibiotics/vaccines. Would really appreciate if people can RT and share with their teams!

1 year ago 27 25 2 2

Chefs kiss

1 year ago 3 0 0 0
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Is there such thing as TEMTuesday? Maybe CryoETuesday? Myelinated axon cross section with microtubules and intermediate filaments:

1 year ago 144 14 10 1

it is nicer over here

1 year ago 6 0 0 0
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