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Posts by Oliver Czarnecki

With #PubMed being down(ed): is this censorship?

#BringPubMedBack

1 year ago 1 0 1 0
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Glucokinase activity controls peripherally located subpopulations of β-cells that lead islet Ca2+ oscillations 3D light-sheet imaging identifies the location and metabolic sensitivity of β-cell subpopulations that lead and coordinate islet Ca2+ oscillations.

Leading the pack: Glucokinase reinforces Ca2+-waves
#PancSky #BetaCellSky

elifesciences.org/articles/103...

1 year ago 8 5 0 1
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Inceptor binds to and directs insulin towards lysosomal degradation in β cells - Nature Metabolism The insulin inhibitory receptor (inceptor) is found to bind to insulin and to regulate insulin stores by directing proinsulin and insulin towards lysosomal degradation.

Thrilled to share one of our biggest discoveries: “Inceptor binds to and directs insulin towards lysosomal degradation in beta cells”.
doi.org/10.1038/s422...
A tremendous collaborative effort led by JohannaSiehler, Sara Bilekova and other members of the Lickert lab @heikolickert.bsky.social

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