“StarPhase: Comprehensive Phase-Aware Pharmacogenomic Diplotyper for Long-Read Sequencing Data” is now on biorxiv! In this work, we explore the use of long-read sequencing (#PacBio #HiFi) for #pharmacogenomics #PGx. 1/N
Pre-print: doi.org/10.1101/2024...
Repo: github.com/PacificBiosc...
Fusion transcript plot
Checkout out a new release of pbfusion (0.5.0) for accurate detection and visualization of fusion transcripts from @pacbio.bsky.social HiFi data.
github.com/PacificBiosc...
Will you be sharing a stream? I'm interested but too far too attend in person.
It's been disappointing to see how universally and transparently even newspapers of record promote boosting the value of capital above all else.
Congratulations!
Which model? Is there a paper?
1/5 We (Nate Brown, @oahmed.bsky.social, Travis Gagie, and @benlangmead.bsky.social) developed Movi, a cache-efficient full-text pangenome index. It's the fastest full-text index for pangenomes, particularly appropriate for adaptive sampling where time budget is important.
Brett + lacto ftw
Ironic coming from RoseTTAFold.
Good lord, the FoldSeek clustering of all AlphaFold structures is incredible. Just stunning. Vastly expands the taxonomic breadth of microbes that encode homologous structures that we care about. Paper here: www.nature.com/articles/s41... and website to search here: cluster.foldseek.com