Join PacBio at ABRF 2026 to see how HiFi sequencing is advancing core facility workflows.
Visit booth #801 to see the Vega system and discuss $300 HiFi genomes with SPRQ-Nx chemistry. We also have new 2026 pricing for Kinnex RNA-seq. See you there!
#ABRF2026 #PacBio #Vega #SPRQNx
Successful AI models are built on data that is high-quality, complete, and rich in biological context.
Basecamp Research is using PacBio HiFi sequencing to move beyond fragmented snapshots and build a richer map of biology.
Read the blog here: bit.ly/4svvj6N
#PacBio #HiFisequencing #Genomics
We gave early access of SPRQ-Nx chemistry to a select group of scientists.
Watch how beta testers like Katy Munson from University of Washington see the workflow and economic benefits of what’s next for #PacBio HiFi sequencing.
On-demand webinar: bit.ly/4szZAS9
#SPRQNx #HiFisequencing
Meet the winners of the 2025 Immunology and Immunotherapy SMRT Grant!
Watch how winners like Numrah Fadra are using the ProfilAIR assay from co-sponsor Clareo Bio. Powered by #PacBio HiFi sequencing, they are closing the technical gap in immune profiling.
Full list of winners: bit.ly/4c5LVwc
Discover how researchers are advancing oncology with PacBio HiFi sequencing at #AACR26! 🔬
HiFi sequencing reveals the full spectrum of cancer biology in a single, unified workflow. We are excited to learn about your research.
Full program here: bit.ly/3NnvTED
#PacBio #CancerResearch
Live webinar: March 27th at 8 AM PT | 11 AM ET. "Resolving Challenging Genetic Variants in Carrier Screening Using Long-Read Technology." Speakers: Theresa Wohlever Customer Success Manager DNAnexus, Jack Roach Computational Scientist Myriad Genetics, Sam Pearlman Senior Software Engineer Myriad Genetics, Deborah Moine Senior Product Manager PacBio, Tom Mokveld Bioinformatics Scientist PacBio.
This week: representatives from Myriad Genetics & @pacbio.bsky.social demonstrate how their long-read sequencing approach successfully improves prenatal carrier screening: event.on24.com/wcc/r/525686...
#Diagnostics #Genetics #StructuralVariants #PacBio #MyriadGenetics #PrenatalScreening
Some of cancer’s biggest drivers are invisible to short reads. In our final Cancer Sequencing 101 episode, we dive into how #PacBio HiFi sequencing brings hidden structural variants into focus.
See the large-scale genomic changes that drive disease: bit.ly/4bFeJdv
#CancerResearch #HiFisequencing
We've just released Minimod v0.5.0! 🧬
Minimod is a fast, lightweight tool for extracting modifications and computing frequencies from aligned BAM files (with MM/ML tags).
Check it out github.com/warp9seq/min...
#Bioinformatics #Genomics #Epigenetics #ONT #PacBio #OpenSource
🧬 Rare ataxias reveal big lessons in human genetics.
In Episode 3, Dr. Birgitt Scheule explains how studying small communities uncovers genetic mechanisms, population patterns, and subtle variants that impact neurological function.
Watch now: bit.ly/4oLrOXu
#PacBio #BeyondTheBench #HiFisequencing
The combination of read lengths up to 20 kb and accuracy >99.9% gives researchers the confidence they need when moving forward in their cell and gene therapy research.
Download our brochure to learn more about the advantages of HiFi for AAV, CRISPR-Cas9, and more: bit.ly/4sSzrNX
#PacBio
Cancer sequencing 101 is back! Today's lesson: Epigenetics.
Watch the next video in the series to learn how researchers use DNA methylation and chromatin accessibility information from HiFi sequencing to power their discoveries.
Full video here: bit.ly/4sjQrgd
#PacBio #CancerResearch #Epigenetics
Think you know long-read sequencing? Put your knowledge to the test.
Assumptions in cancer genomics change fast. At PacBio, we are debunking the biggest myths about cost, FFPE samples, and throughput with the latest HiFi data.
Get the facts: bit.ly/4bks8ZB
#PacBio #CancerResearch #Genomics
PacBio is proud to partner with Basecamp Research to generate high-fidelity metagenomic data for the Trillion Gene Atlas, a landmark initiative to model biological data at the trillion-gene scale and accelerate AI-designed therapeutics.
Learn more here: bit.ly/479RQh3
#PacBio #TrillionGeneAtlas
HiFi = accuracy. But how?
HiFi reads are generated by combining multiple passes around a single DNA molecule. By merging repeated observations, the system produces long reads with greater than 99.9% accuracy.
Watch the full video to see under the hood: bit.ly/3YSPBdo
#TheresHiFiForThat #PacBio
To fully understand cancer, researchers must see the genome and its epigenetic state at once.
Learn how the upcoming SPRQ-Nx chemistry and software release expands #PacBio HiFi sequencing to 5mC, 6mA, and 5hmC with new economics to help you scale.
Read more: bit.ly/3NlDnba
Last call! Join our webinar this week to see how #PacBio HiFi sequencing and spatial transcriptomics reveal deeper insights into cancer than short reads.
Learn about isoform heterogeneity and immune profiling at near-single-cell resolution.
Register here: bit.ly/4bsBanl
Cancer is complex. Your sequencing shouldn’t be.
Discover how #PacBio HiFi sequencing reveals the full spectrum of cancer variation, from structural variants and methylation to RNA isoforms and fusions, in a single technology.
Check out the brochure: bit.ly/4sCizuO
#CancerResearch
How can HiFi sequencing unlock deeper insights into cancer biology than short reads for gene fusions and isoforms?
Our new series shows how researchers use #PacBio to drive discoveries in methylation and structural variation.
Watch here: bit.ly/3P78pnA
#CancerResearch #HiFisequencing
At #ACMGMtg26? Our workshop starts in one hour!
Join Nina Gonzaludo (PacBio) and Lucy Kaplun (Variantyx) in Exhibit Theater 2 to hear how #PacBio HiFi sequencing is streamlining diagnostics research and advancing clinical whole genome testing.
Details: bit.ly/3OBZmee
See you there soon!
Step inside the research shaping the future of cancer genomics.
See how #PacBio HiFi sequencing uncovers hundreds of structural variants, novel isoforms predicting survival, and fusions with treatment implications all in a single technology.
Guide here: bit.ly/4b83Z8E
#CancerResearch
New preprint: Hunting for MSI in long-read data with Owl 🦉
Owl is an MSI caller purpose-built for #PacBio HiFi and integrated into our somatic workflow.
Data:
• Low baseline (~1–5%)
• 15–18% MSI-H instability
• Links GGAA repeats to EWS::FLI1 fusion
Preprint here: bit.ly/4beWECU
Happening today at 12:15 PM!
Join Matt Holt at #ACMGMtg26 for his talk on how #PacBio HiFi sequencing enables the discovery of pharmacogenomic haplotypes.
📍 Platform C
⏰ 12:15 PM
Not attending? Learn more about StarPhase for HiFi PGx in this explainer video: bit.ly/4b4ACUA
A new paper in Cell Genomics validates how #PacBio HiFi sequencing unlocks ASD research.
By replacing multiple assays with one workflow, researchers saw a 33% increase in SV detection and a 38% increase in tandem repeat detection.
Read the study: bit.ly/4sAnkFd
#ASD #PacBio #HiFisequencing
11,674 steps toward hope.
Sean Baumstark, founder of De:terminence, Inc., is climbing the world’s longest stairway this July. Living with Friedreich’s ataxia, his journey reminds us why the work in our labs matters.
Join us at #PacBioPRISM: bit.ly/4bi8AUy
#PacBio #FriedreichsAtaxia
Join #PacBio at #ACMGMtg26 to see how HiFi sequencing is redefining genetic testing. We are featuring two posters presentations:
• P165: CFTR profiling using PureTarget panels (Billy Rowell)
• P636: DNA extraction from low-mass samples (Deborah Moine)
Full program here: bit.ly/3OBZmee
How does HiFi capture epigenetics in one run?
When a base is modified, its incorporation rate shifts. HiFi measures these kinetic signatures to detect 5mC and 6mA automatically with no extra library prep.
Watch our newest explainer video to see how: bit.ly/3YSPBdo
#TheresHiFiForThat #PacBio
Decoding cancer requires resolving transcript diversity within intact tissue.
Join our webinar to see how long-read sequencing and near-single-cell spatial transcriptomics reveal isoform diversity and map immune receptor clonotypes in tumors.
Register: bit.ly/4bsBanl
#PacBio #CancerResearch
The strain is susceptible to #metronidazole, #vancomycin and fidaxomicin, but the #PacBio -generated complete genome shows it harbors different #AMR genes (as is the case for other NTCD).
One molecule. Multiple layers of biology.
HiFi sequencing = multiomic insights.
It reveals the genome, structural variants, full-length isoforms, and base-level methylation. All in one run. All from the same molecule.
Get the full picture: bit.ly/3YSPBdo
#PacBio #HiFisequencing #Multiomics
Live webinar: March 27th at 8 AM PT | 11 AM ET. "Resolving Challenging Genetic Variants in Carrier Screening Using Long-Read Technology." Speakers: Theresa Wohlever Customer Success Manager DNAnexus, Jack Roach Computational Scientist Myriad Genetics, Sam Pearlman Senior Software Engineer Myriad Genetics, Deborah Moine Senior Product Manager PacBio, Tom Mokveld Bioinformatics Scientist PacBio.
Learn how long-read sequencing assays are being deployed to improve prenatal carrier screening: event.on24.com/wcc/r/525686...
#Diagnostics #Genetics #StructuralVariants #PacBio #MyriadGenetics #PrenatalScreening
