Sequencing in 2026:
repeats → resolvable
methylation → built in
SVs → at scale
AI → shaping discovery
The work is more interesting than ever. Explore four-year problems solved in days and results never expected.
Season one is almost over. Stream #BeyondTheBench while you still can: bit.ly/4oLrOXu
🧬 Rare ataxias reveal big lessons in human genetics.
In Episode 3, Dr. Birgitt Scheule explains how studying small communities uncovers genetic mechanisms, population patterns, and subtle variants that impact neurological function.
Watch now: bit.ly/4oLrOXu
#PacBio #BeyondTheBench #HiFisequencing
What happens when a scientist steps outside the lab & meets the people behind the pathology? 🔬
Guest writer Claudia Schrauwen reflects on how volunteering in a rehab centre transformed her perspective on research 👩🔬
Read the article: ow.ly/g8Wj50YsOsI
#beyondthebench #scienceresearch #lifescience
Repeat expansions cause 50+ neurological disorders but are difficult to measure.
Dr. Schuele from Stanford University uses HiFi sequencing to directly profile complex repeats and advance research in Parkinson’s disease and SCA10.
Read about her work: bit.ly/4bz4Y1z
#BeyondTheBench
What happens when a condition shifts from rare to widespread?
In Episode 3 of Beyond the Bench, Dr. Birgitt Scheule explains what it means to shift from studying isolated cases to addressing disease at population scale.
Watch now: bit.ly/4oLrOXu
#BeyondTheBench #PacBio #HiFisequencing
🔬A few amino acid changes can shape whether a lens stays clear for decades or begins to cloud.
In Episode 2, Dr. Andor Kiss explains how his team traces differences tied to stability, adaptation, and cataracts and shares three key findings.
Watch now: bit.ly/4oLrOXu
#BeyondTheBench
New from Miami University: Dr. @andorjkiss.bsky.social and his lab’s work featured in BEYOND THE BENCH.
Students are generating long-read sequencing data in-house and learning how sequencing strategy shapes discovery.
Read the story: bit.ly/4aFSgMS
#BeyondTheBench #PacBio #HiFisequencing
Key takeaway from Dr. Santosha Vardhana in Beyond the Bench:
When T cells run low on energy, they make priority decisions that shift into self preservation mode. That bioenergetic limit shapes immune exhaustion.
Watch the full episode: bit.ly/4oLrOXu
#BeyondTheBench
Not all immune cells behave like the textbooks say.
New blog: Dr. Santosha Vardhana shows how HiFi long-read RNA is exposing hidden transcript isoforms + real immune diversity in cancer datasets.
If you build hypotheses off single-cell data, this one’s worth a read: bit.ly/4rypwN3
#BeyondTheBench
Why do people fall in love with biology?
For Dr. Santosha Vardhana, it’s awe at how much the human body gets right. That sense of wonder still shapes how he thinks about cancer, the immune system, and discovery.
Watch his story in BEYOND THE BENCH → bit.ly/4oLrOXu
#BeyondTheBench
@pacbio.bsky.social
launched a new series called
#BeyondTheBench; they interviewed me and the work we're doing in the Center For Bioinformatics & Functional Genomics (CBFG) with their new #VEGA Benchtop Long-Read Sequencer #MiamiOH #HiFi #Methyl-Seq #KINNEX #Science
www.pacb.com/beyond-the-b...
🎬✨Now streaming: BEYOND THE BENCH
This season features:
• Santosha Vardhana on immune cell exhaustion and RNA splicing
• Andor Kiss on bringing HiFi into teaching
• Birgitt Schüele on repeat expansions across populations
Press play → bit.ly/4oLrOXu
#BeyondTheBench #PacBio #TheresHiFiForThat
You voted and the verdict is in. Everyone unwinds differently off the clock.
For the researchers in Beyond the Bench, the results varied. A crossword at dawn. A hand built turntable. Miles on a mountain trail.
Meet them in our latest blog: bit.ly/4pH7jfB
#PacBio #BeyondTheBench #Blog
Holiday watchlist shaping up? ❄️🎄🎁
Save a spot for BEYOND THE BENCH, a #PacBio series that follows science through the people behind the discoveries. There is always more to genomics than meets the eye.
Sign up for the January premiere: bit.ly/4oLrOXu
#BeyondTheBench #PacBio #TheresHiFiForThat
🚀 Beyond the Bench Talks — with Springer Nature!
Join us for a deep dive into book publishing & innovation with experts from Springer Nature.📚✨
🗓 1 Dec 2025
⏰ 13:00–15:00 CET
🔗 Register via the QR code in the poster!
#BeyondTheBench #IYCN #IUPAC #SpringerNature #SciComm #STEMCareers