Thank you Annemarthe for having accepted to be part of the jury !

Photo of Charline and her jury members after the defense

Today was a great day for Charline Pasquier, who successfully defended her PhD thesis in front of the jury composed of @annemarthe.bsky.social @ericci-aeruginosa.bsky.social, Stefania Millevoi and Jean-Luc Imler. Congratulations to her for a brilliant defense! 🍾

#InterferonPower! Thrilled for our latest work @cp-cell.bsky.social! With @danielboehmer.bsky.social, we dug into tons of papers & created what we hope will be a go-to resource for immunologists & non-immunologist about type I, II, III (& IV😉) #interferons! Free👉 authors.elsevier.com/a/1leKGL7PXu...

@sebpfeffer.bsky.social , @agencerecherche.bsky.social , @unistra.fr

Fatty Acid Synthase binds endogenous dsRNAs and dampens the innate immune response to exogenous dsRNAs by limiting their accumulation. In mammalian cells, the presence of double-stranded RNA (dsRNA) in the cytoplasm is a danger signal indicative of viral infection. Cells establish and maintain an antiviral state via the production of...

I am happy to share our last preprint, where we identified FASN as an endogenous dsRNA-associated factor and demonstrated that its depletion triggers endodsRNA accumulation and a stronger antiviral response to exogenous dsRNAs,#RNA, #interferon,#immunometabolism
www.biorxiv.org/cgi/content/...

First Patient Treated with Personalized CRISPR Therapy, Developed in Just Six Months The first on-demand CRISPR therapy for an infant with a rare metabolic disease developed by the IGI and collaborators around the world.

This is what can be achieved today due to longstanding federal support of academic basic science alongside close partnership of universities, private industry and NIH intramural initiatives. An ecosystem worth not just saving but doubling down on!

innovativegenomics.org/news/first-p...

So honored and happy to share that I was awarded the 2024 Guy Ourisson Prize. A big thank you to my mentors, colleagues, and students, past and present, without whom it would have never been possible!

🙋🏻‍♀️please

🙋🏻‍♀️please

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