NEW STUDY by Kaveh R. Khalilpour, et al. at UTS shows links between #AlzheimersDisease & #Gut #Health can lead to prevention. Learn More @alzdemjournals.bsky.social ➡️ alz-journals.onlinelibrary.wiley.com/doi/10.1002/... Overview from University of Technology Sydney ➡️ www.uts.edu.au/news/2026/04...

Neutrophil inflammation metrics are associated with the risk of future dementia in large data from NYU Langone Hospitals and the Veterans Health Administration INTRODUCTION Neutrophil-to-lymphocyte ratio (NLR), a marker of systemic inflammation, has been linked to dementia risk, but prior studies were limited by small sample sizes. METHODS We assessed th.....

New study by Nate Fillmore, Jaime Ramos-Cejudo, et al. shows high neutrophil to lymphocyte ratio could ID patients at risk of dvlping #Alzheimers & related #Dementias before they exhibit signs of cognitive impairment. @alzdemjournals.bsky.social👉
alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

An incredible audience w/ fantastic feedback at my last talk at 23rd Annual Society for Brain Mapping & Therapeutics Neurotech Conference: "Late Onset of #AlzheimersDisease computational modeling"! As the conference nears its end, thank you SBMT & Dr Babak Kateb for organizing such an amazing event.

On Friday, April 17, the World Brain Mapping Foundation held its annual "Gathering for Cure" Awards Gala. It was a fantastic event! I was so proud and humbled to have been selected to receive the 2026 Golden Axon Leadership Award. It is a wonderful honor. Thank you Dr. Babak Kateb & SBMT!

Evaluating the peripheral nervous system pathology of Alzheimer's disease utilizing a functional human NMJ microphysiological system INTRODUCTION Alzheimer's Disease (AD) is a central nervous system (CNS) neurodegenerative disease leading to dementia, but can also show symptoms of motor deficits. It is not clear whether the perip...

Researchers Akhmetzada Kargazhanov, Romy Aiken, Kenneth Hawkins, et al. @ucf.bsky.social have uncovered evidence some movement-related symptoms of #Alzheimers may originate outside the brain.

Alzheimers & Dementia | @alzassociation.bsky.social
alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

LANDMARK STUDY from researchers Ashok Shetty, et al. @tamu.bsky.social suggests the inflammatory tide responsible for brain aging and brain fog might actually be reversible. @tamuvetmed.bsky.social Learn More in Journal of Extracellular Vesicles 👉 isevjournals.onlinelibrary.wiley.com/doi/10.1002/...

Conductive Hearing Loss Pathologies are Associated With Dementia in the All of Us Research Program Objective Recently, conductive hearing loss (CHL) has been associated with dementia in two large independent cohorts. However, the disease-specific association with dementia is unknown. We investiga...

NEW RESEARCH by Justin Golub, et al. finds that two common & treatable causes of conductive hearing loss are associated with higher odds of #Dementia.

Learn More from the American Academy of Otolaryngology - Head and Neck Surgery Foundation
aao-hnsfjournals.onlinelibrary.wiley.com/doi/10.1002/...

The primary aim of this study was to examine plant-based dietary patterns and their change over time in relation to #AlzheimersDisease and related #Dementias.

Learn More in Neurology
www.neurology.org/doi/10.1212/...

Overview @neurosciencenews.bsky.social
neurosciencenews.com/plant-based-...

Jeremy Herskowitz, et al. at UAB discovered tau “seeds” travel primarily along an individual’s unique, natural communication pathways confirming personal neuronal wiring dictates how fast & far #Alzheimers advances, providing definitive target for antibody therapies. 👉
www.cell.com/neuron/fullt...

NEW STUDY from Praveen Rao, et al. @uwaterloo.ca investigated potential of combining antibody treatments with natural small molecule inhibitors known for their anti-amyloid properties, specifically #Resveratol and #Curcumin.

Learn More in ACS Chemical Neuroscience
pubs.acs.org/doi/10.1021/...

MORE INTERESTING RESEARCH! Led by Marilyn Rampersad Mackiewicz @osuscience.bsky.social, a team of researchers have uncovered real-time insights into a chemical process linked w/ #Alzheimers, paving the way toward better drug designs. Learn More in ACS Omega news.oregonstate.edu/news/researc...

Older adults who received a high-dose inactivated influenza vaccine had a lower risk of incident #AlzheimersDisease dementia compared with those who received a standard-dose shot, U.S. claims data showed. Learn More in Neurology
www.neurology.org/doi/10.1212/...

The microtubule nexus linking amyloid beta and tau: A simple and unifying theory for the underlying cause of Alzheimer's disease Abstract. Alzheimer's disease (AD) is defined by cognitive decline in conjunction with accumulation of aggregated amyloid β (Aβ) and tau, yet existing mode

GREAT PAPER! In a new study, Thomas Shoff, Maxence Derbez-Morin, Peishan Cai, and Ryan Julian @ucriverside.bsky.social offer a "unifying theory" that resolves some conflicting ideas about #AlzheimersDisease. Learn More @pnasnexus.org 👉 academic.oup.com/pnasnexus/ar...

Society for Brain Mapping & Therapeutics's 23rd Annual Neurotech Conference is 2 WEEKS AWAY! Looking forward to connecting w/ Rudolph Castellani, George Perry & Christopher Wheeler to discuss latest #Neurotech innovations in #Alzheimers & #Dementia. JOIN US! Register Now 👉 www.worldBrainMapping.org

A Chirality‐Guided Molecular Recognition Strategy for Targeting Intrinsically Disordered Proteins The present study provides the systematic investigation of stereocomplexation between complementary L- and D-short peptides. This stereocomplexation is predominantly driven by hydrophobic and electro...

Interesting Research! Alzheimer’s has long been considered “undruggable” because the proteins involved lack a fixed shape for traditional drugs to latch onto. Researchers @kobeuniv.bsky.social have found a solution. Learn More in ChemEurJ ➡️ chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...

A deep joint-learning proteomics model for diagnosis of six conditions associated with dementia - Nature Medicine ProtAIDe-Dx is a deep joint-learning model that uses plasma proteomics to provide simultaneous probabilistic diagnoses across six conditions associated with aging.

Different #Neurodegenerative conditions can present w/ similar symptoms, making it difficult to distinguish btwn them. Now, researchers Jacob Vogel, Lijun An, et al. have dvlpd an #AI model capable of detecting multiple diseases at once. Learn More in Nature Medicine 👉 www.nature.com/articles/s41...

Translocation of bacteria from the gut to the brain in mice Recent studies link gut dysbiosis to neurological disease, but the underlying mechanisms remain unclear. This study shows that a high-fat diet increases gut permeability and enables bacterial transloc...

The #GutBrainAxis has long been known for its indirect chemical signaling, but a groundbreaking study by Arash Grakoui, et al. @emoryuniversity.bsky.social suggests a much more direct interaction. Learn More @plosbiology.org 👉 journals.plos.org/plosbiology/...

MISSED IT? Study by Eun-Jeong Yang, Giulio Maria Pasinetti, et al. reveals regulatory T cells, crucial components of immune system, might also influence #AlzheimersDisease type neuropathology & cognitive functions. CHECK OUT this #PasinettiLab study @pnasnexus.org 👉 academic.oup.com/pnasnexus/ar...

A great day at Making the Impossible Possible (MIPO) Youth Summit. Metropolitan College of New York (MCNY) was proud to be represented by @weillcornell.bsky.social's Dr. Greta Strong & Dr. Hamilton Raymond w/ special recognition to MCNY MBA alumna NY State Assemblymember Monique Chandler-Waterman.

The role of noninfectious comorbidities in the association between severe infections and risk of dementia in Finland: A nationwide registry study In a registry-based study, Pyry Sipilä and colleagues investigate the role of non-infectious mental and physical illnesses in the association between severe infections and dementia using nationwide da...

Severe infections have been linked to increased risk of #Dementia. However, it has been unclear whether this assoc is explained by other coexisting, non-infectious diseases that predispose people to both infections & dementia. Learn More @plosmedicine.org 👉 journals.plos.org/plosmedicine...

Meat Consumption and Cognitive Health by APOE Genotype This cohort study investigates the association of meat consumption with risk of cognitive decline and dementia among older adults with APOE genotypes ε3/ε4 and ε4/ε4.

INTERESTING RESEARCH from @ki.se! Older people with a genetic risk of #AlzheimersDisease did not experience the expected increase in cognitive decline and #Dementia risk if they consumed relatively large amounts of meat. Learn More @jamanetworkopen.com ➡️ jamanetwork.com/journals/jam...

Blood-brain barrier disruption, traumatic encephalopathy, and cognitive decline in retired athletes Blood-brain barrier disruption is associated with cognitive decline and complement system activation in retired athletes.

A NEW STUDY by Chris Greene, Declan Brennan, Colin Doherty, Matthew Campbell, et al. has identified a leaky #BloodBrainBarrier (BBB) as the primary mechanism linking repetitive head injuries to long-term cognitive decline in retired athletes. Learn More @science.org 👉 www.science.org/doi/10.1126/...

Adherence to the MIND diet and longitudinal brain structural changes over a decade: evidence from the Framingham heart study offspring cohort Background The MIND diet was favourably linked to lower risk of neurodegenerative diseases. While previous cross-sectional studies implied its beneficial associations with brain imaging markers, its a...

In this prospective cohort study by Hui Chen, Gulisiya Hailili, Lu-sha Tong, et al., greater adherence to the #MINDDiet was associated w/ slower brain structural atrophy, particularly regarding grey matter loss & ventricular enlargement. Learn More at jnnp.bmj.com 👉 jnnp.bmj.com/content/earl...

In a new study, @dukemedschool.bsky.social researchers Vincent D’Anniballe, Sarah Kim, John Finlay, Bradley Goldstein, et al. show that a quick, outpatient nasal swab can pick up early biological changes linked to #Alzheimers. Learn More in Nature Communications 👉 www.nature.com/articles/s41...

Ca2+-phospholipid-dependent regulation of Munc13-1 is essential for post-tetanic potentiation at mossy fiber synapses and supports working memory López-Murcia et al. demonstrate that Ca2+-dependent regulation of the vesicle-priming protein Munc13-1 supports synaptic short-term facilitation and post-tetanic potentiation at hippocampal mossy fibe...

A NEW STUDY by Francisco José López-Murcia, Nils Brose, et al. has identified a molecular pathway in the brain that is crucial for the proper functioning of working memory. @unibarcelonathe.bsky.social @maxplanck.de Learn More in @cp-cellreports.bsky.social 👉 www.cell.com/cell-reports...

Rodrigue Brossaud, Michel Neunlist, Moustapha Cissé, et al. investigated possibility Aβ accumulates in both brain & gut of patients w/ #Alzheimers, which can also damage connections that promote healthy digestion, contributing to AD progression. Molecular Psychiatry www.nature.com/articles/s41...

Researchers @meredithbraskie.bsky.social, et al. have ID'd important differences in how early #AlzheimersDisease -related brain changes appear across racial & ethnic groups. LEARN MORE @alzdemjournals.bsky.social 👉 alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

A repeat expansion in GOLGA8A is a major risk factor for atypical frontotemporal lobar degeneration with ubiquitin-positive inclusions - Nature Genetics Genome-wide analysis coupled with long-read sequencing identifies a repeat expansion in GOLGA8A associated with high risk for atypical frontotemporal lobar degeneration with ubiquitin-positive inclusi...

FANTASTIC! Researchers Wouter De Coster, Marleen Van den Broeck, Matthew Baker, @joannambi.bsky.social, Rosa Rademakers, et al. have ID'd a major genetic risk factor for rare form of #FrontoTemporalDementia. @uantwerpen.be @viblifesciences.bsky.social @mayoclinic.org 👉 www.nature.com/articles/s41...

I am so proud and grateful to have been selected to receive the Society for Brain Mapping & Therapeutics' 2026 Golden Axon Leadership Award. It is a wonderful honor. Thank you Dr. Babak Kateb and the World Brain Mapping Foundation Boards.- Dr. Giulio Maria Pasinetti

A new study by researchers Ahrum Son, Hyunsoo Kim, Jolene Diedrich, John Yates III, et al. suggests #AlzheimersDisease may be detectable through subtle shape changes in proteins found in the blood. Learn More in Nature Aging | @natureportfolio.nature.com 👉
www.nature.com/articles/s43...