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Posts by Bose Lab Sheffield

Exciting new packages!! Very cool ❄️ to see the new microscope (JEMma) added to the cryoEM facility to keep @AvaArctica company @sheffielduni.bsky.social @mcb-sheffield.bsky.social! (Ok, it does look a little bit like a washing machine!) lookout for more details soon!

1 year ago 1 1 0 0
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The conformational space of RNase P RNA in solution - Nature Using a deep neural network and statistical analyses of atomic force microscopy images of individual RNA molecules enables the mapping of RNA conformational space in solution.

Amazing #RNA structural ensembles! Really highlights how important #singlemolecule approaches are for finding mechanism in sustems and models that move! www.nature.com/articles/s41...

1 year ago 10 2 0 0
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Cooperation between Intrinsically Disordered Regions regulates CBP condensate behaviour Creb binding protein (CBP) and EP300 (p300) are transcription coactivators that bind at cis -regulatory elements and regulate gene expression in multicellular organisms. They contain large intrinsical...

Posting this awesome work from the summer led by Katie in our team- currently undergoing some exciting new upgrades :) www.biorxiv.org/content/10.1...

1 year ago 9 2 0 0

With some help from @raduzabet.bsky.social, I've created a starter pack of researchers working on #Epigenetics, Chromatin and Gene Regulation who are active on here:
go.bsky.app/TKp9YAn
I've likely missed many people so let me know if you want to be added. Similarly if you would like to be removed.

1 year ago 117 69 61 1

Fantastic, well articulated review reconciling how regulatory complexes at the molecular level function in the context of transcriptional condensates.

1 year ago 1 1 0 0
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Can I ask you to share a PhD advert at Bristol Uni please? Rhomboid proteases play a role in neurons that is essential for life- but it is not characterised. Got a student interested in cell biology, electrophysiology and neurobiology? Send them our way! tinyurl.com/56f24f7c

1 year ago 72 80 0 4
https://www.rug.nl/about-ug/work-with-us/job-opportunities/?details=00347-02S000B06P

Fellow #RNA lovers, please repost πŸ™: 2 ERC-funded Post-doc positions are available in our lab to investigate #RNA structural ensemble and their dynamics in living cells. Application link: t.co/pYJ3H3j705

1 year ago 35 49 0 2

Bringing the lab account over too!! Check us out at @bose-lab.bsky.social 🧬πŸ₯ΌπŸ§ͺβš—οΈπŸ”¬πŸͺ΄

1 year ago 6 2 0 0
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