And,

To the contrary,

This is not lets-propose-this-and-see-what-Congress-says. Their plan is more like USAID: eliminate before Congress can weigh in.

AS PER MY LAST POST:

Google's AI Overview scanned a hoax paper (loaded with Star Wars references) that @neuroskeptic.bsky.social wrote.

AI Overview said "Kyloren syndrome" is a real disease.

See "The garbage'll do", July 2017, in Stinging the Predators:

bit.ly/StingPred

(aside from being conveniently squished in the vertical dimension with a non-functioning pop-out button)

I'm curious how these plots on year-to-year NIH funding levels compare to those @jeremymberg.bsky.social has been compiling. In my recollection, they're meaningfully different than the ones he was showing at the @biophysicalsoc.bsky.social meeting.

grants.nih.gov/news-events/...

A full disc image of Earth, as seen from the Orion Crew Module. The planet is a pale blue, swirling with white clouds and glowing slightly lighter blue in place from reflected light. At lower left, a large brown landmass is Africa, with Spain and Portugal with twinkling lights where the planet curves. At top right, auroras glow in a thin green glow, just barely separated from the planet's surface. Earth is set against the black of space (pic: NASA/R.Wiseman)

More context on this #Artemis II image:

* This is the night side, lit by moonlight. You can see city lights in Spain & Portugal, & a sliver of day at lower right

* The Sun is entirely behind Earth, which makes it a kind of solar eclipse, but w/ Earth doing the eclipsing instead of the Moon:
☀️🌍🚀🌕

"Experts are Dubious" !?!?

THE TRUMP TRAP.

Do not give up your integrity to keep your job, your funding, your lab, your organization, your science…you’ll end up with neither.

If you wait for them to forcefully take it, you still have your integrity.

Choose wisely, history watches.

Screenshot of HR software showing "Michelle McCully" listed as the poster's name

After almost 10 years, my name is finally right in SCU's digital systems 🎉🎉 Depending on how implementation rolls out, my students and advisees should finally know how to find me, I shouldn't miss as many communications and payments. Thanks to the HR/IS team who make it happen!! #WomeninSTEM

Another informative and thought provoking piece by @dereklowe.bsky.social

…Noem was just fired because of public pressure, articles of impeachment getting serious, and tanking polls. And immigration has ALWAYS BEEN Trump’s number one issue. He shoots the hostage every time.

Why would he spare an unpopular Kennedy?

RFK Jr is not a sacred cow.

Meet three scientists who said no to Epstein The warning signs included a web search, a mother’s doubts, and inklings of a “sexist attitude”

What a good idea for an article! Very interesting. It's worth contemplating whether you would have also recognized the warning signs -- or have someone in your life who would.

www.science.org/content/arti...

I mean, it's this, or we just send chatbot-written e-mails back and forth to each other forever

MARCH 7, USA TAKE BACK our SCIENCE RALLY! ALL ACROSS THR COUNTRY NATIONWIDE DAY OF ACTION SAVE SCIENCE. PROTECT HEALTH. DEFEND DEMOCRACY. standupforscience.net/march7

Let's hit the streets on Saturday, March 7th! The mission is simple: Save Science, Protect Health, Defend Democracy. Find a rally near you, start your own, or just get some friends together and have a pop-up protest! Links in bio, or visit standupforscience.net/march7

#science
#standupforscience

I’m looking to hire a research technician for my lab at Harvard & DFCI, who would primarily work in the wet lab expressing and characterizing designed proteins, starting this summer. A great role for a recent college grad looking for an immersive research experience before grad school.

Hi everyone, I earned my PhD from the Department of Child Study and Human Development. My studies, research, and professional work focus on how positive media use among children and young people… |... Hi everyone, I earned my PhD from the Department of Child Study and Human Development. My studies, research, and professional work focus on how positive media use among children and young people ca...

DOCTOR Rümeysa Öztürk has earned her PhD!!

@altfda.altgov.info challenged us to list #5Things that each of us Alts think have caused the most damage in our agencies over the past year. Each of the five items is chock full of sub-items…adding up to far more “things.” Here goes.

We should also note that these vaccines were limited to the most vulnerable populations or not approved at all due to these rare side effects (1 in 200,000). And now this detective work will help ensure future vaccines are even safer. Truly important work!

#goals @ncfdd.org

Preaching to the choir, but...

I'm giving an exam but have slept in, forgotten to make copies, forgotten to write it, etc.

When I was a student, never in a million years would I have suspected that my professors were having nightmares about the same exams as I was -- but from the opposite side!

Undergraduates Rosetta Commons Research Experience for Undergraduates (REU) AI for Biomolecular Structure Prediction and Design Interns in this geographically-distributed REU program participate in research using…

Final stretch to apply for undergraduate summer internships in the Rosetta Commons! Come design proteins, develop AI and physics-based methods to model biomolecules, and impact health, materials, and sustainability! Application deadline is Sunday Feb 1.
rosettacommons.org/education/reu/

Stand With Minnesota Donation Directory Stand With Minnesota is a hub for supporting, learning, and taking action to support Minnesotans impacted by ICE and federal enforcement.

Do what you can.

❤️‍🩹Take care of yourself.
🫂Take care of each other.
☎️Call 5calls.org
🧑‍💻Write democracy.io#!/thanks
🚫Boycott ICE: www.boycottcitizens.org/ice
✊Support MN: www.standwithminnesota.com

Vibrant color portrait of Jane S. Richardson, the visionary biophysicist and artist who revolutionized structural biology with her invention of ribbon diagrams. She gazes warmly at the camera with a bright, knowing smile that radiates quiet brilliance and decades of curiosity. Her silver-blonde hair woven with gentle waves. Large, elegant dangling earrings catch the light, and she wears a richly patterned brown blouse embroidered with intricate turquoise paisley motifs and delicate beadwork that echoes the molecular elegance she has spent her life depicting. Behind her floats a luminous, dreamlike backdrop of glowing molecular structures--interlocking hexagonal and ribbon-like forms in electric blues, teals, and greens--blending science and art in a single, living canvas.

Hand-drawn and hand-colored (by Jane Richardson) scientific artwork known as a Richardson ribbon diagram (or “ribbon model”), one of the iconic visual inventions of Jane Richardson that transformed the way we see and understand protein structures. A graceful, three-dimensional tangle of protein backbone ribbons twists and spirals through space, rendered in soft pencil lines and luminous watercolor hues. Smooth golden-brown coils represent α-helices that curl like elegant ribbons, while broad teal-green arrows trace the flat, pleated strands of β-sheets slicing through the molecule with directional purpose. Thin, looping golden threads connect the secondary structures, creating a delicate, almost dance-like choreography of biology’s hidden architecture. The entire form is framed by a simple olive-green mat and dark border, giving the drawing the quiet dignity of both fine art and precise scientific illustration—a timeless bridge between molecular reality and human imagination.

Jane Richardson was born #OTD in 1941

+ Developed the Richardson (ribbon) diagram to represent proteins' 3D structure (becoming a standard representation for protein structures)
+ MacArthur Fellow, 1985
+ Elected, Nat'l Academy of Sciences, 1991
+ President, Biophysical Society, 2012

#WomenInSTEM

Mutual aid fundraiser poster for Lyndale Community School

We've raised a lot of money for my school community neighbors.

And I predict all of it will be depleted by the end of this week.

If you're in a position to donate, please help: paypal.me/lyndalepto

(donations are tax deductible)

3/3

Here’s a preprint from the Keating Lab: www.biorxiv.org/content/10.6.... Foster Birnbaum and Amy E. Keating demonstrate that sequence design models, such as ProteinMPNN, are limited because they were trained only on native sequences.

Opinion: Stop Asking If People Want to Ride Bikes — Streetsblog USA "We shouldn’t be aiming to nudge a few percentage points in public opinion. Our goal should be to make freedom of mobility so compelling that people demand it."

“We shouldn’t be aiming to nudge a few % points in public opinion. Our goal should be to make freedom of mobility so compelling that people demand it. Help people visualize & demand a future where kids can bike to school, seniors can walk to stores, couples can bike to dinner.” @usa.streetsblog.org

Here for the right reasons

Computational design of conformation-biasing mutations to alter protein functions Conformational biasing (CB) is a rapid and streamlined computational method that uses contrastive scoring by inverse folding models to predict protein variants biased toward desired conformational sta...

Exciting new work from @aliceyting.bsky.social and coworkers @stanfordbiosci.bsky.social @stanfordmedicine.bsky.social

www.science.org/doi/10.1126/...