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Posts by Chuck Herring

Comparative single cell analysis of wound and cancer identifies the metabolic dialogues between tumor initiating stem cells and macrophages #SingleCell ๐Ÿงช๐Ÿงฌ๐Ÿ–ฅ๏ธ
www.biorxiv.org/content/10.64898/2026.04...

2 weeks ago 1 1 0 0

annbatch unlocks terabyte-scale training of biological data in anndata #SingleCell ๐Ÿงช๐Ÿงฌ๐Ÿ–ฅ๏ธ
https://arxiv.org/abs/2604.01949

2 weeks ago 1 1 0 0

Generating and navigating single cell dynamics via a geodesic bridge between nonlinear transcriptional and linear latent manifolds #SingleCell ๐Ÿงช๐Ÿงฌ๐Ÿ–ฅ๏ธ
www.biorxiv.org/content/10.64898/2026.03...

2 weeks ago 1 1 0 0
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Excited to share currently confirmed speakers for HCA Asia 2026 (lnkd.in/gEQPj3Gk)!

#SingleCell #Genomics #SpatialBiology #SpatialOmics #HumanCellAtlas #SingleCell #transcriptomics #multiomics #Spatial_transcriptomics

@ozsinglecell.bsky.social
@lornegenome.bsky.social

1 month ago 4 2 1 0

GPU-accelerated single-cell analysis at scale with rapids-singlecell #SingleCell ๐Ÿงช๐Ÿงฌ๐Ÿ–ฅ๏ธ
https://arxiv.org/abs/2603.02402

1 month ago 3 2 0 0

Differential analysis of genomics count data with edge #SingleCell ๐Ÿงช๐Ÿงฌ๐Ÿ–ฅ๏ธ
www.biorxiv.org/content/10.64898/2026.02...

2 months ago 1 1 0 0

Evaluating Single-Cell Perturbation Response Models Is Far from Straightforward #SingleCell ๐Ÿงช๐Ÿงฌ๐Ÿ–ฅ๏ธ
www.biorxiv.org/content/10.64898/2026.02...

2 months ago 3 1 0 0
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Registration for the HCA Asia Meeting on 2-4 November, 2026 is now open! The #HCA2026Asia meeting will be held in Perth, Australia, and online, and is hosted by @alforrest.bsky.social. Please register at buff.ly/gADDEnC
๐Ÿ–ฅ๏ธ ๐Ÿงฌ #Genomics #SingleCell #Spatial #HumanCellAtlas

2 months ago 3 3 1 1
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This was a great read, thank you for sharing.

2 months ago 0 0 1 0
A a figure showing comparison of connectomeDB2025 to other ligand-receptor pair databases.

A a figure showing comparison of connectomeDB2025 to other ligand-receptor pair databases.

connectomeDB2025: Quality matters!
โœ…3,579 ligand-receptor pairs supported by 2,803 papers
โœ…14 vertebrates
โŒ >2,900 unsupported pairs from other DBs excluded

connectomedb.org

academic.oup.com/nar/advance-...

@JARamilowski @sakura_maezono @rui_hou_ @weitao_lin @yen_yeow + team

5 months ago 9 3 1 0

@ginaravenscroft.bsky.social & #NARF are collecting impact statements from Australian researchers

โ€˜ Please consider sharing your story about the impact of Australia's chronic underfunding of science and biomedical research.โ€™
lnkd.in/g8A_PAZG

1/

4 months ago 20 14 1 1

Every opportunity politicians provide for you to tell them about how chronic underfunding of research in Australia is affecting your particular fields, people, working conditions etc. is extremely important.

Fill out the form here: lnkd.in/g8A_PAZG

4 months ago 30 26 0 1

If your #NHMRC ideas grant was unsuccessful and you have a story to share about the impact of this on your #biomedicalresearch, career, team - get in touch. Federal DOH have asked #NARF to collect stories of impact of low funding. #SaveOzScience #DiscoveriesNeedDollars #EMCRs

1 year ago 34 36 2 1
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Speakers โ€” Lorne Genome No description found

Last chance! Early bird rates and oral presentation abstract submissions for Lorne Genome ๐ž๐ง๐ ๐๐จ๐ฏ๐ž๐ฆ๐›๐ž๐ซ ๐Ÿ•๐ญ๐ก, ๐Ÿ๐ŸŽ๐Ÿ๐Ÿ“ - only one week away: https://www.lornegenome.org/registrations

We have a fantastic lineup of national and international speakers: https://www.lornegenome.org/speakers Join us!

5 months ago 6 6 0 0

velotest: Statistical assessment of RNA velocity embeddings reveals quality differences for reliable trajectory visualizations #SingleCell ๐Ÿงช๐Ÿงฌ๐Ÿ–ฅ๏ธ
www.biorxiv.org/content/10.1101/2025.10....

5 months ago 2 1 0 0

Igniting full-length isoform analysis in single-cell and spatial RNA-seq data with FLAMESv2 www.biorxiv.org/content/10.1101/2025.10....

6 months ago 3 2 0 0
Registrations โ€” Lorne Genome Registrations are now open! Secure your ticket to attend Lorne Genome 2022!

Don't forget to register and submit an abstract for the ๐‹๐จ๐ซ๐ง๐ž ๐†๐ž๐ง๐จ๐ฆ๐ž ๐Ÿ๐ŸŽ๐Ÿ๐Ÿ”!

๐“๐ก๐ข๐ฌ ๐ฐ๐ž๐ž๐ค'๐ฌ ๐ฌ๐ฉ๐ž๐š๐ค๐ž๐ซ ๐ฌ๐ฉ๐จ๐ญ๐ฅ๐ข๐ ๐ก๐ญ: ๐๐ซ๐จ๐Ÿ ๐๐ซ๐ž๐ง๐๐š ๐€๐ง๐๐ซ๐ž๐ฐ๐ฌ, a leading systems biologist whose research focuses on mapping genetic interaction networks and protein localisation patterns in yeast and human cells.

6 months ago 4 3 0 0

The Fragile X mental retardation protein (FMRP) coordinates an epigenetic checkpoint in neural progenitor cells www.biorxiv.org/content/10.1101/2025.08....

7 months ago 2 1 0 0
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Whole-transcriptome-scale and isoform-resolved spatial imaging of single cells in complex tissues #SingleCell ๐Ÿงช๐Ÿงฌ๐Ÿ–ฅ๏ธ
www.biorxiv.org/content/10.1101/2025.08....

7 months ago 1 1 0 0
Emma Whitelaw Publication Award โ€” Australasian Epigenetics Alliance

๐Ÿงฌ The 2025 Emma Whitelaw ECR publication award is now open!

Full T&Cs and application form are on the AEpiA website www.aepia.org.au/emma-whitela...

We can't wait to see the exciting research that has been published over the last year!

#epigenetics #ECR #research #AEpiA

7 months ago 4 7 0 0

My generation had to deal with datasets where Excel had autocorrected gene names to dates. Future generations are going to have to deal with the hallucinations of slopbots.

8 months ago 45 20 0 0

Disentangling the influences of pre- and postnatal periods on human cortical microstructure www.biorxiv.org/content/10.1101/2025.08....

8 months ago 3 3 0 0

Especially important for all the microscopy Widdors out there.

9 months ago 1 0 1 0

Beautiful paper, congrats all involved.

9 months ago 1 0 0 0
Video

Worth a watch:

Head of Signal, Meredith Whittaker, on so-called "agentic AI" and the difference between how it's described in the marketing and what access and control it would actually require to work as advertised.

9 months ago 10991 4394 203 725
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This is a piece that I and @karsten-rippe.bsky.social discussing a lot, and a topic that is very close to my heart. The editors @naturerevgenet.bsky.social gave us the stage to do so, and the final version of our review is now available under this link: rdcu.be/erP1u

A short thread follows 1/n

10 months ago 95 39 3 2

Extrinsic biological stochasticity and technical noise normalization of single-cell RNA sequencing data www.biorxiv.org/content/10.1101/2025.05....

11 months ago 3 2 0 0

Can't remember who said it, but using ChatGPT for your college essays is like using a forklift to move the weights around at the gym.

It's the process that's important to your development, not the end product.

11 months ago 1897 323 61 21
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It was new to me and our lab as well. Thanks for sharing.

11 months ago 2 0 0 0
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Zero-shot evaluation reveals limitations of single-cell foundation models - Genome Biology Foundation models such as scGPT and Geneformer have not been rigorously evaluated in a setting where they are used without any further training (i.e., zero-shot). Understanding the performance of mode...

genomebiology.biomedcentral.com/articles/10....

Quite an indictment of some of the current single cell "virtual cell" foundation models. Even for the relatively mundane applications, cell labeling, batch correction etc, they are poor compared to much simpler & cheaper methods.

1 year ago 158 47 6 3