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Posts by Clรกudia Vilhena

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One month ago, me and my partner finally got to see our best and most challenging 9-month project coming out! ๐Ÿฅฐ We're super excited to see how the co-authored project develops!๐Ÿฃ

(Vilhena & Bouthillier, 2026)

#newPI #newMum #womeninSTEM #muminSTEM #muminScience

1 month ago 11 0 0 0

#VAAM2026 is kicking off today in Berlin!๐Ÿฆ 
The #BIDlab will be represented by the fantastic Miriana Battista who will be presenting our latest work on Poster IB-024 on Tuesday ๐Ÿ™Œ๐Ÿป๐Ÿ™๐Ÿป๐Ÿ‘Œ๐Ÿป๐Ÿ˜ stop by!

#microbiology #streptococcuspneumoniae #extracellularvesicles

1 month ago 1 0 0 0
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Happy new year!! Let's do the work to make this year better than the last.

2 months ago 22 3 0 0

๐Ÿ™๐Ÿป๐Ÿ™๐Ÿป

2 months ago 1 0 0 0
Internationaler Tag fรผr Frauen und Mรคdchen in der Wissenschaft โ€“ Interview mit Dr. Grace Androga โ€“ Infect-Net

To celebrate the International day of #womenandgirlsinscience, I had the pleasure to interview Dr. Grace Androga! ๐Ÿ™Œ๐Ÿป

infectnet.org/en/archive/4...

Enjoy the reading and keep giving women the stage!
#womeninSTEM #womeninsience

@infect-net.bsky.social

2 months ago 4 0 0 0

โฌโฌ๐Ÿ™๐Ÿป๐Ÿ™๐Ÿป๐Ÿ‘ฉ๐Ÿพโ€๐Ÿ”ฌ๐Ÿ‘ฉ๐Ÿผโ€๐Ÿš€๐Ÿ‘ฉ๐Ÿฟโ€๐Ÿซ๐Ÿ‘ฉ๐Ÿพโ€๐Ÿ”ฌ

2 months ago 2 0 0 0
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Bacterial immune activation via supramolecular assembly with phage triggers - Nature An antiphage defence system has an activation mechanism thatย relies on the sensing of phage-encoded proteins that enforce geometry crucial to activation and are not typically present in non-infected cells.

Nature research paper: Bacterial immune activation via supramolecular assembly with phage triggers

go.nature.com/4tmW9iw

2 months ago 17 5 0 1
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The status of extracellular vesicles as drug carriers and therapeutics - Nature Reviews Bioengineering Extracellular vesicles (EVs) are emerging as biocompatible carriers for targeted drug delivery, yet challenges in yield, cargo loading and biodistribution persist. In this Review, key trends from over a decade of research are analysed, comparing EVs with lipid-based systems and outlining strategies for improving therapeutic translation and reporting standards.

Extracellular vesicles (EVs) are emerging as biocompatible carriers for targeted drug delivery. A Review in Nature Reviews Bioengineering compares EVs with lipid-based systems and outlining strategies for improving therapeutic translation and reporting standards. ๐Ÿ”’

2 months ago 15 1 0 0
Ein Park, der schneebedeckt ist. Eine Person geht in der Ferne durch den Schnee.

Ein Park, der schneebedeckt ist. Eine Person geht in der Ferne durch den Schnee.

Heute am besten lieber mit Schlittenhunden zur Uni fahren ๐Ÿ•โ€๐Ÿฆบ

2 months ago 136 12 4 1

Awesome!! Congrats Viola ๐Ÿ˜๐Ÿ˜

2 months ago 0 0 0 0
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The #BIDlab had a super productive cookie-baking last workday with the PharmBio team ๐Ÿช ๐ŸŽ„

Closing the year extremely thankful for all the work and development we did as a small team๐Ÿ‘ฉ๐Ÿ”ฌ ๐Ÿงช

Enjoy the holidays and see y'all in 2026! ๐Ÿฅณ ๐Ÿ™

#newPI #streptococcuspneumoniae #extracellularvesicles

4 months ago 0 0 0 0
Stilisierte Illustration einer Rakete, die aus einem dichten Netzwerk aus verbundenen Punkten in den Weltraum startet โ€“ Symbol fรผr Weiterentwicklung, Vernetzung und Aufbruch von Infect-Net.

Stilisierte Illustration einer Rakete, die aus einem dichten Netzwerk aus verbundenen Punkten in den Weltraum startet โ€“ Symbol fรผr Weiterentwicklung, Vernetzung und Aufbruch von Infect-Net.

Homepage Relaunch ๐Ÿš€ Wir haben ein paar ร„nderungen an unserer Website vorgenommen. Alle ร„nderungen und neuen Features auf infectnet.org haben wir hier fรผr euch kompakt zusammengefasst: ๐Ÿ‘‰ infectnet.org/archive/4096
#InfectNet #Version1.2 #Relaunch #Frauennetzwerk #Infektionsforschung

4 months ago 8 5 1 0

Thank youu๐Ÿ’œ

5 months ago 0 0 0 0

๐Ÿงต2/2 In this work, we utilize a cocultivation platform to explore #extracellularvesicles formation at the interface between #bacteria and the human host and provide first insights into regulatory molecular mechanisms. ๐Ÿงซ ๐Ÿฆ 

5 months ago 0 0 0 0
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Mechanistic Insights into the Role of Extracellular Vesicles at the Bacterialโ€“Host Interface Bacterial and human cells produce extracellular vesicles (EVs) in response to diverse stimuli, e.g., toxins, oxidative stress, nutrient depletion, or high cell density. Here, we describe a cocultivation platform that allows recovery of mixed extracellular vesicles (mix-EVs) produced simultaneously by both cell types. We investigated interactions between Gram-positive and Gram-negative bacteria (Streptococcus pyogenes, Staphylococcus aureus, Escherichia coli, and Neisseria meningitidis) and human peripheral blood mononuclear cells (PBMCs). The production of the mix-EVs population decreased with higher bacterial concentrations. Exposing PBMCs to mix-EVs repressed the general transcriptomic signature, in contrast with a significant upregulation generated by single bacterial-EVs. However, mix-EVs-derived IL-1ฮฒ upregulation was confirmed at the protein level. Inhibition experiments showed that IL-1ฮฒ production involved TLR2 and TLR4 signaling, acting through IRAK-1 and TRAF6 related pathways. This approach provides a new platform for the study of EVs at the pathogenโ€“host interface and presents mechanistic insights into the effect of EVs on an infected host.

๐Ÿงต1/2- So so happy to share our very first publication from the #BIDlab! ๐Ÿฅณ ๐ŸŽ‰ ๐Ÿ™

A huge thanks to our super talented PhD student Miriana Battista and our amazing collaborators @appsysbio.bsky.social and Christoph Saffer for the work and support ๐Ÿ‘Œ ๐Ÿ™

โฉ pubs.acs.org/doi/full/10....

5 months ago 7 2 2 0

Today is #WorldPneumoniaDay ๐Ÿซ๐Ÿฆ ๐Ÿ˜ท
Even though steps have been taken to tackle this deadly infectious disease, a long road still lies ahead.

To mark this day, I wrote a short article for @infect-net.bsky.social ๐Ÿ“– English version will come soon!

5 months ago 2 0 0 0
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How jealous are you that your lab is not based in Germany on Nov. 11th? ๐Ÿคค๐Ÿ˜‹

#BIDlab

5 months ago 1 0 0 0
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Super happy to see our interview out on Trillium EVs journal! ๐Ÿ‘Œ๐Ÿป๐Ÿคฉ

Check out the full article โฌ
trillium.de/en/journals/trโ€ฆ

#newPI #BIDlab #extracellularvesicles

6 months ago 1 0 0 0
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Thanksss๐Ÿฅบ๐Ÿคฉ we'll keep moving and pushing

6 months ago 1 0 0 0

๐Ÿงต #2 and 1 under revision, went to 4 conferences, integrated into the local research community and we're still enjoying the journey ๐Ÿฅ‚๐Ÿธ๐Ÿน it is very draining and frustrating at times, but we'll keep moving ๐Ÿ™Œ๐Ÿป
A huge Thank you to everyone that supported us along the way๐Ÿ™๐Ÿป

6 months ago 0 0 0 0
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The #BIDlab is 1 year old! ๐ŸŽ‚๐Ÿ™๐Ÿป๐Ÿ‘ฉ๐Ÿปโ€๐Ÿ”ฌ๐ŸŽ‰๐Ÿฅณ๐Ÿ‘ฏ
๐Ÿงต#1 On Oct 1st 2024 we started this crazy journey: 1 junior group leader, 1 PhD student, a small office and a tiny budget.
Ups&downs and a lot of hard work later, we have enlarged the group, got funding in, have 1 accepted paper and

6 months ago 6 2 2 0
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The #BIDlab got to show it's work at #GSEV2025 on a talk, flash talk and poster! ๐Ÿงซ๐Ÿ”ฌ๐Ÿ™๐Ÿป
Super proud of our PhD student Miriana for her first flash talk๐Ÿ™๐Ÿป great work ๐Ÿ™Œ๐Ÿป

@isev.org @gsevorg.bsky.social
#extracellularvesicles #streptococcuspneumoniae #newPI

6 months ago 2 1 0 0

Oh man such a great idea, wished I had thought of it before. unfortunately schedule is super tight ๐Ÿ˜ซ

6 months ago 1 0 1 0
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The #BIDlab is already in Essen for the German Society of #extracellularvesicles autumn meeting!๐Ÿฆ ๐Ÿงซ๐Ÿ”ฌ
We'll be busy with a talk, poster, flash talk and loads of networking! #Pneumy will be just chillin'
@gsevorg.bsky.social

#streptococcuspneumoniae
#labmascot
#GSEV2025

6 months ago 8 1 1 0
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The #BIDlab is very honored to have received funding from the Dr. Hertha und Helmut Schmauser-Stiftung to develop our projects on bacterial EVs lipidomics! ๐Ÿ˜ ๐Ÿ™ stay tuned for next developments!
#extracellularvesices #bacteria #streptococcuspneumoniae #newPI

7 months ago 3 0 1 0

The first preprint of our #BIDlab!! ๐Ÿคฉ
Short story on our favorite organism #streptococcuspneumoniae and our beloved #extracellularvesicles!
#newPI #fingerscrossed

9 months ago 2 1 0 0

Environmental cues shape extracellular vesicles biogenesis and function in Streptococcus pneumoniae www.biorxiv.org/content/10.1101/2025.07....

9 months ago 3 1 0 1
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It's a wrap! #EESMicrobiology #Pneumy #BIDlab

9 months ago 2 0 0 0
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#Pneumy is ready for the poster session! ๐Ÿค“๐Ÿฆ 
Stop by #60 and #252 from the #BIDlab ๐Ÿ™Œ๐Ÿป

#EESMicrobiology
#streptococcuspneumoniae #extracellularvesicles #newPI

9 months ago 2 0 0 0
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The #BIDlab made it to EMBL Heidelberg to attend the fantastic #EESMicrobiology conference! ๐Ÿ˜Ž ๐Ÿฆ ๐Ÿ”ฌ

We have 4 days, 2 poster presentations and countless good microbiological talks over rooftop drinks ahead!๐Ÿท
@events.embl.org

#streptococcuspneumoniae #extracellularvesicles #newPI #Pneumy #labmascot

9 months ago 8 0 2 0