#VAAM2026 is kicking off today in Berlin!🦠
The #BIDlab will be represented by the fantastic Miriana Battista who will be presenting our latest work on Poster IB-024 on Tuesday 🙌🏻🙏🏻👌🏻😍 stop by!

#microbiology #streptococcuspneumoniae #extracellularvesicles

The #BIDlab had a super productive cookie-baking last workday with the PharmBio team 🍪 🎄

Closing the year extremely thankful for all the work and development we did as a small team👩🔬 🧪

Enjoy the holidays and see y'all in 2026! 🥳 🙏

#newPI #streptococcuspneumoniae #extracellularvesicles

Mechanistic Insights into the Role of Extracellular Vesicles at the Bacterial–Host Interface Bacterial and human cells produce extracellular vesicles (EVs) in response to diverse stimuli, e.g., toxins, oxidative stress, nutrient depletion, or high cell density. Here, we describe a cocultivation platform that allows recovery of mixed extracellular vesicles (mix-EVs) produced simultaneously by both cell types. We investigated interactions between Gram-positive and Gram-negative bacteria (Streptococcus pyogenes, Staphylococcus aureus, Escherichia coli, and Neisseria meningitidis) and human peripheral blood mononuclear cells (PBMCs). The production of the mix-EVs population decreased with higher bacterial concentrations. Exposing PBMCs to mix-EVs repressed the general transcriptomic signature, in contrast with a significant upregulation generated by single bacterial-EVs. However, mix-EVs-derived IL-1β upregulation was confirmed at the protein level. Inhibition experiments showed that IL-1β production involved TLR2 and TLR4 signaling, acting through IRAK-1 and TRAF6 related pathways. This approach provides a new platform for the study of EVs at the pathogen–host interface and presents mechanistic insights into the effect of EVs on an infected host.

🧵1/2- So so happy to share our very first publication from the #BIDlab! 🥳 🎉 🙏

A huge thanks to our super talented PhD student Miriana Battista and our amazing collaborators @appsysbio.bsky.social and Christoph Saffer for the work and support 👌 🙏

⏩ pubs.acs.org/doi/full/10....

How jealous are you that your lab is not based in Germany on Nov. 11th? 🤤😋

#BIDlab

Super happy to see our interview out on Trillium EVs journal! 👌🏻🤩

Check out the full article ⏬
trillium.de/en/journals/tr…

#newPI #BIDlab #extracellularvesicles

The #BIDlab is 1 year old! 🎂🙏🏻👩🏻‍🔬🎉🥳👯
🧵#1 On Oct 1st 2024 we started this crazy journey: 1 junior group leader, 1 PhD student, a small office and a tiny budget.
Ups&downs and a lot of hard work later, we have enlarged the group, got funding in, have 1 accepted paper and

The #BIDlab got to show it's work at #GSEV2025 on a talk, flash talk and poster! 🧫🔬🙏🏻
Super proud of our PhD student Miriana for her first flash talk🙏🏻 great work 🙌🏻

@isev.org @gsevorg.bsky.social
#extracellularvesicles #streptococcuspneumoniae #newPI

The #BIDlab is already in Essen for the German Society of #extracellularvesicles autumn meeting!🦠🧫🔬
We'll be busy with a talk, poster, flash talk and loads of networking! #Pneumy will be just chillin'
@gsevorg.bsky.social

#streptococcuspneumoniae
#labmascot
#GSEV2025

The #BIDlab is very honored to have received funding from the Dr. Hertha und Helmut Schmauser-Stiftung to develop our projects on bacterial EVs lipidomics! 😍 🙏 stay tuned for next developments!
#extracellularvesices #bacteria #streptococcuspneumoniae #newPI

The first preprint of our #BIDlab!! 🤩
Short story on our favorite organism #streptococcuspneumoniae and our beloved #extracellularvesicles!
#newPI #fingerscrossed

It's a wrap! #EESMicrobiology #Pneumy #BIDlab

#Pneumy is ready for the poster session! 🤓🦠
Stop by #60 and #252 from the #BIDlab 🙌🏻

#EESMicrobiology
#streptococcuspneumoniae #extracellularvesicles #newPI

The #BIDlab made it to EMBL Heidelberg to attend the fantastic #EESMicrobiology conference! 😎 🦠🔬

We have 4 days, 2 poster presentations and countless good microbiological talks over rooftop drinks ahead!🍷
@events.embl.org

#streptococcuspneumoniae #extracellularvesicles #newPI #Pneumy #labmascot

The #BIDlab is again on the move! 🚄 Attending tomorrow the New approaches and concepts in microbiology conference in beautiful Heidelberg🦠🔬🍇
See y'all there! embl.org/about/info/cou… via @embl.org @events.embl.org

#EESMicrobiology #streptococcuspneumoniae #newPI

And so it ends! 🦠🐳 The #BIDlab had a great time at #Europneumo2025 in #Açores🇵🇹

Can't wait to see the community again in Bologna 2027! #streptococcuspneumoniae #extracellularvesicles #newPI

And so it begins! 👏🏻👌🏻
#Europneumo2025 #BIDlab #extracellularvesicles #streptococcuspneumoniae

First impressions of the super green #Europneumo2025 venue #Açores #Portugal 🇵🇹🌴🌲🌳

#BIDlab #newPI #extracellularvesicles #streptococcuspneumoniae

Taking some days off to recharge in #Portugal🇵🇹 before heading to #Europneumo2025

#BIDlab #newPI

New Funding for Exciting Projects in Extracellular Vesicles The newly established Junior Research Group for Bacterial Interface Dynamics led by Dr. Cláudia Vilhena has recently received support from two foundations to advance and sediment the research on…

Really looking forward to the next steps! 🤩
#BIDlab #extracellularvesicles #newPI
@nat.fau.de @fau.de

www.biology.nat.fau.eu/2025/04/30/a...

Really happy to share that I recently joined the board of the Optical Imaging Center Erlangen (OICE)🔬🙏🏻 I'm honored and excited to take up this new responsibility and to continue to use this amazing facility 🦠👩🏻‍🔬
#newPI #BIDlab

Thanks @ra-pa.bsky.social 🙏🏻

www.oice.fau.de

Big news for the #BIDlab 🎉 we just got support from not one, but two sources to push our research forward!✌🏻😍 Super excited for what’s coming next. More details soon👩🏻‍🔬👩🏻‍💻 #newPI #keeppushing

Last day of #VAAM2025 @vaam-microbes.bsky.social ✨ The first conference of the #BIDlab 🤩🥇 we had a great time catching up with old friends, making new ones, with exciting scientific exchanges and a lot more energy to go back to the lab! 💪🏻👩🏻‍🔬🦠

Hey #immunology #cellbiology folks. We're having a hard time imaging human cellular junctions🫠We've tried different antibody concentrations, permeabilization and fixation methods, but nothing seems to work.
Any advice? 🙏🏻🙏🏻

#BIDlab #newPI #sciencehelp

The press release on the graduation day at the Department of Biology @faunat.bsky.social @fau.de is out!🤩

It was a great pleasure and challenge to give the lecture to students, family and friends 🙌🏻🙏🏻

#newPI #newchapter #BIDlab

www.biologie.nat.fau.de/2025/02/25/a...

Back in the #darkroom

#happyplace
#microscopy
#BIDlab

First poster of the #BIDlab from the super talented PhD student Miriana Battista! 🤩📚♀️

Today at the "PhD day" from the Department of Biology 🌿🧬🦠 @faunat.bsky.social @fau.de

#womeninscience #WomenInSTEM #newPI #proudPI

BID lab logo

The #BIDlab has a logo! 🔬🧫👩🏻‍🔬🧪🦠 What do you guys think?🙏🏻

#homemade #smallsteps #enjoythejourney #newPI

The #BIDlab 🚺♀️ wishes a great #WomenInScience #WomenInSTEM day to all our girls out there! 🙏🏻👌🏻 #keeprocking

🎉 ¡Completamos IAceleradora 2.0! Del 18 al 22 de noviembre, nos capacitamos en inteligencia artificial gracias a ConnectAmericas de BIDLAB. Este logro nos permite ofrecer mejores servicios a las pymes, impulsando su innovación y crecimiento. 🚀 #IAceleradora #Pymes #BIDLAB