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Posts by Francisco Amaro

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New in JB: In the CF airway, P. aeruginosa transitions from an acute to chronic pathogen. Roxana Flores-Vega, Roberto Rosales-Reyes et al. review the role of 2-component systems in this crucial adaptation.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology

2 weeks ago 21 13 1 1
False color scanning electron microscopy image of E. coli bacteria. Image by Gerd Altmann from Pixabay

False color scanning electron microscopy image of E. coli bacteria. Image by Gerd Altmann from Pixabay

Why are there so few #pathogens, and what determines their emergence? @jdrakephd.bsky.social ‬argues that #ecological and #evolutionary forces (host availability, geographic exposure and microbial innovation) will shape future human diseases. 🧪
plos.io/4mUst87

8 months ago 15 5 4 0
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Why are there so few pathogens? Ecology and evolution in pathogen emergence Why are there so few pathogens, and what determines their emergence? This Perspective argues that ecological and evolutionary forces (host availability, geographic exposure and microbial innovation) w...

journals.plos.org/plosbiology/...

#MicroSky

8 months ago 1 1 0 0
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Deep learning reveals antibiotics in the archaeal proteome - Nature Microbiology Use of artificial intelligence to mine proteomes of archaea led to the discovery of archaeasins, antimicrobials that kill drug-resistant bacteria in laboratory and animal models, offering a promising ...

(1/5)For over a century, the hunt for new antibiotics has focused almost exclusively on bacteria and fungi. Today, that paradigm shifts. By coupling state-of-the-art AI with the vast, largely uncharted diversity of Archaea, we open a new frontier for molecular discovery.

8 months ago 53 23 1 0
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Infections as ecosystems: community metabolic interactions in microbial pathogenesis | Infection and Immunity Microbial communities are present on nearly every surface of the human body. These microbiomes exist as dynamic ecosystems that are influenced by heterogeneous nutritional and chemical landscapes, the...

Excited to have our new mini review on Microbiome Metabolism out today in I&I as part of the @asm.org New Voices in Microbiology collection! Check it out!

🧫🧪

journals.asm.org/doi/10.1128/...

8 months ago 39 16 1 0
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La odisea de tres mujeres y el BO-112, la molécula que engaña al cáncer La líder científica, la empresaria y una paciente libre de enfermedad se reúnen para contar la historia completa del prometedor fármaco experimental español contra los tumores

La odisea de tres mujeres y el BO-112, la molécula que engaña al cáncer
elpais.com/ciencia/2025...

8 months ago 24 11 2 1
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A chemical radar allows bacteria to detect and kill predators Pseudomonas syringae can detect and kill microbial predators via a chemical radar (Cra), which also allows the bacterium to infect plants despite predation pressure.

chemical crosstalk at a distance of 𝘗𝘴𝘦𝘶𝘥𝘰𝘮𝘰𝘯𝘢𝘴 𝘴𝘺𝘳𝘪𝘯𝘨𝘢𝘦 with 𝘗𝘰𝘭𝘺𝘴𝘱𝘩𝘰𝘯𝘥𝘺𝘭𝘪𝘶𝘮 𝘱𝘢𝘭𝘭𝘪𝘥𝘶𝘮 amoebae. oh nos, this does not end well for the amoebas...

www.cell.com/cell/fulltex...
#MicroSky

1 year ago 17 8 0 0
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Release of extracellular DNA by Pseudomonas sp. as a major determinant for biofilm switching and an early indicator for cell population control Biological sciences; Microbiology; Microbiofilms

Release of extracellular DNA by Pseudomonas sp. as a major determinant for biofilm switching and an early indicator for cell population control

@cp-iscience.bsky.social from Frank Delvigne

www.cell.com/iscience/ful...

1 year ago 19 8 0 0
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Nobel Prize in Physiology or Medicine 1905 The Nobel Prize in Physiology or Medicine 1905 was awarded to Robert Koch "for his investigations and discoveries in relation to tuberculosis"

Hoy 24 de marzo se conmemora el Día Mundial de la Tuberculosis, en recuerdo del día en que se publicó la identificación de Mycobacterium tuberculosis como la bacteria responsable de la enfermedad. Robert Koch recibió el Premio Nobel por ello en 1905.
www.nobelprize.org/prizes/medic...

1 year ago 1 1 0 0
Ending Tuberculosis in the Face of Antimicrobial Resistance | ASM.org Despite thousands of years of dealing with tuberculosis, it remains the leading cause of death by infectious diseases worldwide. Can multi-drug resistant TB be combated?

Despite thousands of years of dealing with tuberculosis, it remains the leading cause of death by infectious diseases worldwide. Can multi-drug resistant TB be combated? asm.org/Articles/202... #WorldTBDay

1 year ago 4 4 0 0
Image based on a figure in the paper illustrating risk factors and main clinical characteristics of tuberculosis infection and disease.

Image based on a figure in the paper illustrating risk factors and main clinical characteristics of tuberculosis infection and disease.

Image based on a figure in the paper illustrating risk factors and main clinical characteristics of tuberculosis infection and disease.

Image based on a figure in the paper illustrating risk factors and main clinical characteristics of tuberculosis infection and disease.

Image based on a figure in the paper illustrating risk factors and main clinical characteristics of tuberculosis infection and disease.

Image based on a figure in the paper illustrating risk factors and main clinical characteristics of tuberculosis infection and disease.

When a person is diagnosed with #tuberculosis, one of their first questions is often, “Why did I get tuberculosis? Why me?” 💬

Explore a recent Seminar which aims to help healthcare providers identify those at risk of TB & address patient concerns: tinyurl.com/3pvhxtbp #WorldTBDay

1 year ago 20 11 0 3

The gut-lung axis: Protozoa join the party #protists #protistsonsky #holobiont

1 year ago 4 1 0 0

Enhorabuena!!! Soy fan!!

1 year ago 1 0 1 0
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Streptomyces secretes a siderophore that sensitizes competitor bacteria to phage infection - Nature Microbiology A secondary metabolite sensitizes competitor Bacillus subtilis to a wide panel of lytic phages by sequestering iron and preventing the activation of Spo0A.

Another newly discovered mechanism of bacteria inhibiting competitors - increasing their sensitivity to phages - fascinating
www.nature.com/articles/s41...

1 year ago 33 12 1 2

Protists as mediators of complex microbial and viral associations www.biorxiv.org/content/10.1... #jcampubs

1 year ago 9 2 0 1
Figure showing the different steps of assembling, firing and disassembling of a Type Six Secretion System

Figure showing the different steps of assembling, firing and disassembling of a Type Six Secretion System

Sharing in #BlueSky a 2023 review on #T6SS that I loved co-authoring with my fantastic friend and collaborator @lukeallsopp.bsky.social He coined the catchy, musical first part of our title: "Killing in the Name of: T6SS Structure and Effector Diversity" Check it out: buff.ly/3Zzh0Rz #Microbiology

1 year ago 52 18 2 3
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Sepsis is a life-threatening, heterogeneous disorder involving a dysregulated immune response to infection. Research to identify subtypes and targeted therapies for host dysregulation is ongoing #idsky #EMIMCC #medsky
www.nejm.org/doi/full/10....

1 year ago 13 4 0 0
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RNA-seq reproducibility of Pseudomonas aeruginosa in laboratory models of cystic fibrosis | Microbiology Spectrum RNA sequencing (RNA-seq) has revolutionized biology, but many steps in RNA-seq workflows can introduce variance, potentially compromising reproducibility. While reproducibility in RNA-seq has been tho...

Different approaches to preparing and sequencing bacterial RNA libraries capture comparable transcriptional profiles:
journals.asm.org/doi/10.1128/...

#microsky #PsWatch #bacteria

1 year ago 8 7 0 0
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These mouth bacteria use a new type of cell division to make 14 cells at once The newfound strategy seen in C. matruchotii might help oral bacteria recover lost territory after each eviction by toothbrushing.

Crazy stuff in PNAS

dental plaque bacterium 𝘊𝘰𝘳𝘺𝘯𝘦𝘣𝘢𝘤𝘵𝘦𝘳𝘪𝘶𝘮 𝘮𝘢𝘵𝘳𝘶𝘤𝘩𝘰𝘵𝘪𝘪 can divide into an unprecedented 14 daughter cells at once—then each daughter cell starts growing immediately in a rare process called multiple fission, achieving 0.5 mm per day of expansion

www.snexplores.org/article/bact...

1 year ago 346 114 17 16
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Complex transcriptional regulations of a hyperparasitic quadripartite system in giant viruses infecting protists - Nature Communications Giant viruses infecting protists can be hyperparasitized by virophages, and carry mobile DNA elements called transpovirons. Here, Bessenay et al. analyze the transcriptional program of this complex qu...

www.nature.com/articles/s41...

1 year ago 21 10 3 1
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Shigella sonnei: epidemiology, evolution, pathogenesis, resistance and host interactions Nature Reviews Microbiology - In this Review, Scott et al. review our current knowledge of Shigella sonnei, highlighting recent insights into this globally disseminated antimicrobial-resistant...

Recent review on Shigella sonnei rdcu.be/d1DGx

1 year ago 29 13 0 0
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@lthwatermicro.bsky.social glad to see you here on 🔵bsky, catherine 👋

why not start here with the eye-opening video of "looking closer & closer at 𝘌. 𝘤𝘰𝘭𝘪" that you posted on 𝕏 on Apr 10, 2019 ?
#MicroSky

1 year ago 18 5 1 1
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Through The Pilus by Roberto — Among the many mechanisms of bacterial horizontal gene transfer, conjugation, the plasmid-mediated cell-to-cell movement of DNA, holds a special place in the heart of this old-timer E. co...

@kellygoldlust.bsky.social glad to see you here, kelly 😊 you might have noticed that we featured your paper in STC >
schaechter.asmblog.org/schaechter/2...

1 year ago 13 6 0 0

Just did my first Starter Pack, I think it can be useful. Let me know if you miss any journal and I will add it. Enjoy!! go.bsky.app/QPFZpj9

1 year ago 150 78 21 5
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@jamesweiss.bsky.social @jamesweiss.bsky.social we would very much like to see your marvelous clip of Leptophrys here again (you had it on 𝕏 in 2020)
#ProtistsOnSky

1 year ago 27 8 1 1

Extremely happy to see the final published version of this study out in Nature Ecology and Evolution www.nature.com/articles/s41...
I really think this is one of our most important contributions to the field!

1 year ago 7 3 0 0
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Agents of change: a partnership between mobile genetic elements facilitates rapid bacterial adaptation While the evolutionary interests of mobile genetic elements may differ from those of their bacterial hosts, these elements can be beneficial for their hosts by delivering, disrupting, or activating ge...


Agents of change: a partnership between mobile genetic elements facilitates rapid bacterial adaptation

#TrendsMicrobiol Spotlight by Elizabeth Duan, @oliviakosterlitz.bsky.social and Benjamin Kerr

on the Nat Eco Evo paper from @sanmillan.bsky.social group

www.cell.com/trends/micro...

1 year ago 55 26 1 0