Outstanding work from @jovanakaljevic.bsky.social as together with the team they explore the depths of ParB world🤩

On my list!

Versatile NTP recognition and domain fusions expand the functional repertoire of the ParB-CTPase fold beyond chromosome segregation | PNAS Nucleotide triphosphate (NTP)-dependent molecular switches regulate essential cellular processes by cycling between active and inactive states thro...

Our preprint is now published in PNAS! This came together thanks to a great collaboration with Antoine Hocher and a strong team effort from the Le Lab. Thank you to the reviewers and to everyone who helped improve it. I hope ParB aficionados will enjoy it.

www.pnas.org/doi/10.1073/...

Wow, what an honor!
The @biophysicalsoc.bsky.social awards me the esteemed '2026 Kazuhiko Kinosita Award in Single-Molecule Biophysics'
'for groundbreaking contributions to the field of nanobiology and single-molecule biophysics, from nanopores to SMC molecular motors'.

Feel honored, very thankful!

Absolutely preposterous size of a Giant Sequoia…

Here's a new very exciting paper from our #CDlab: www.cell.com/cell-reports...

In an exemplary in vitro/in vivo study, 1st authors ‪@btanalikwu.bsky.social‬ & Alice Deshayes showed that dense linear protein arrays (e.g. telomeres) do stop loop-extruding SMCs!

Great collaboration with Marcand lab.

Wrapped up a GRC on Bacterial Cell Biology and Development last week in SNHU, New Hampshire.

A full week of talks on novel bacterial systems and new mechanistic details on eastablished systems.

Great chance to learn, connect with peers and enjoy science!

We're excited to host two fantastic speakers at our next online @physicsoflifeuk.bsky.social ECR Seminar on Tuesday 15 April, 2–3 PM BST:
Tisma Milos and Thomas McLean
chaired by @veronicabiga.bsky.social

Please register below for the Zoom link:
lnkd.in/dSynrAe8

I must say while he mentions ethics and transparency of his results he did have strange requests on X/Twitter:
- requested upfront to have his 2018 results published in Science or Nature
- continuously has strange financial request to give a talk at a major US university

The Man Who Used Gene Editing On Babies - Jiankui He YouTube video by BioAcc Podcast

Just watched a podcast with Jiankui He, the first person to go. through with CRISPR editing in human babies in 2018.

He started a complex debate (both in productive and destructive ways) on ethics in science, future of gene editing and safety of current methods.



www.youtube.com/watch?v=ch03...

I remember your birthday email along the lines of:
“65 looked really old when I was a student, but I am bursting with enegy, gratitude and health so I’m ready for new adventures!”

A lovely visit to Yale School of Medicine to see @leoschaerfen.bsky.social graduate with a spectacular PhD work.
🤩

Biologist-"Let me order some Biotin-11-dUTP"

Chemist-"Let me order some ((2R,3S,5R)-5-(2,4-dioxo-5-(3-(6-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexanamido)prop-1-yn-1-yl)-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl hydrogen triphosphate"
😅

Legitmately thrilled to share our latest work, in which @fernpizza.bsky.social solved an experimental challenge in plasmid biology as old as the field: measuring how plasmids compete and evolve within individual cells!

These protests are unique in their nature as they are:
- entirely apolitical
- peaceful
- lead by students, and no single party or individual leading them
- they have reignited hope, kindness and huge support in a country of wilted spirit due to corrupt government in the past couple of years

Scientists rally in support of Serbia’s anticorruption protests But some criticize “weak and formal” support for protests from scientific institutions

Nice to see that Science(.org) supports and spreads awareness of the massive protests currently ongoing in Serbia!

Peaceful protests lead by Serbian University students (later joined by many others), have gathered more than 200 000 people on occasions!

www.science.org/content/arti...

This is so real 🤣🤣

I do not know the explanation of this but definitely resonates very well…

What is the multiscale structure of chromatin condensates? How does it shape thermodynamic and material properties?

We address this at near-atomistic resolution🔥🔥🔥 using cryoET (Rosen & Villa labs, led by H Zhou), a new multiscale model (K Russell) and cryoET-guided sims (J Huertas & J Maristany)

Congrats to #CDlab graduate ‪Miloš Tišma for winning a Rubicon grant to pursue postdoc research on antibiotic resistance at Harvard Medical School!

Thanks Cees! Obviously a huge part of this is the work and freedom I had in CD lab! 🙏🏼

And to quote the committee “recommendation letters that are somewhat hyperbolic in tone”
🙊

Thank youu!

Thankss!🙏🏼

Thanks to all that helped me with the ideation, application, and editing!

Glad to receive the trust and recognition in being awarded a Dutch NWO Rubicon Fellowship for important work on antibiotic resistance.

I will be tackling this problem using a combination of biophysics, biochemistry and microbiology in Joe Loparo lab at Harvard Medical School (Dept. of BCMP).

About the price of a hefty GPU workstation, close to a student’s annual consumables cost in the lab, attendence to 5 conferences, full week of Krios data collection, cost of ~100 samples for proteomics data collection… so many things to better spend the money than these outrageous publishing fees.

The truth is nobody should care how many protein coding genes there are. The gene is a useful abstraction that loses its utility when defined precisely enough to count.

Thank youu! It’s been an important part of our journeys☺️

Congratulations on this! 🤩

I’ll move directly to giving unsolicited advice as postdocs often do🙈

This will be me in a few months when i come back @btanalikwu.bsky.social and Jaco 🤣🙈