🥁 Check out our new preprint on OmniPath, the prior knowledge resource for #SystemsBiology, and its brand-new OmniPath Explorer web app! 🥳
📖 Preprint: www.biorxiv.org/content/10.1...
🔍 Explorer: explore.omnipathdb.org
OmniPath integrates 160+ resources for multi-omics analysis & modeling.
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"increasing reports of AI hallucinations making their way into academic papers, court decisions, and White House reports [that] have been caught by humans; One wonders how many haven’t been identified and are being spread across the information ecosystem" www.science.org/doi/10.1126/...
Two charts present survival rates for childhood leukemia over time, specifically focusing on Acute Lymphoblastic Leukemia (ALL) and Acute Myeloid Leukemia (AML). In the top panel, for ALL, a series of curved lines represent overall survival rates plotted against years since diagnosis. The lines show a marked increase in survival rates from the late 1960s, when only 14% of children survived more than five years post-diagnosis, to around 94% in the 2010s. Key intervals are labeled, with different colors indicating different periods of diagnosis, ranging from 1972-1975 to 2010-2015. The bottom panel illustrates survival rates for AML, which are consistently lower overall compared to ALL. Like the top graph, it features several colored lines indicating specific periods. The highest point noted indicates a survival rate of 65%. The graph captures trends in survival as well, showing gradual improvement over time, from 1975-1977 up to 2011-2017. Data sources for these visualizations are cited at the bottom: Mignon Loh et al. (2023) for ALL and Todd M Cooper et al. (2023) for AML, both from the Children's Oncology Group. The chart is published by Our World in Data, and licensed under Creative Commons by the author, Saloni Dattani.
I wrote a new piece on how much progress has been made in treating childhood leukemia.
The answer is: quite a lot!
Before the 1970s, fewer than 10% of children diagnosed survived 5 years after diagnosis.
Now most are cured and around 85% survive that long.
ourworldindata.org/childhood-le...
The astounding contribution of US academic science to new medicines
www.statnews.com/2025/06/06/u...
Fractal dimension and Sphericity are keywords that come to mind-both can be calculated numerically. For the former, there is an R package (voxR?)
A great blog post (3rd in the series!) from the BIRS meeting in Canada. This time by @evolsci.bsky.social @glorenzogz.bsky.social @rrockne.bsky.social amongst others
Biophysically-Constrained GBM Predictions via Deep-Learning Integrating Structural SINDY with Mechanistic Filters
New post on shallowness of Deep Research AI tools, and solutions that don’t really solve the problems we often face as scientists: kucharski.substack.com/p/the-shallo...
Please don’t stop sharing and posting your science because of the current attack on it, it is still valuable and reminds us what the fight is for
Space–time scaling of dominance in macroevolutionary modes
Stephen J Gould (1985) talked about the "tiers of time" with macroevolutionary dynamics distinct from short-time microevolution.
But did you know that macroevolution itself shows qualitatively different dynamics at different time scales?
www.nature.com/articles/s41...
🧪 #EvoBio #Paleobio ⚒️ #Geology
🚨 Annual IMPRS Call for Doctoral Positions at MPI-EvolBio 🚨
🎓 Fully-funded 3.5-year doctoral projects available in diverse research areas!
#PhD #ResearchOpportunities #IMPRS #Science evolbio.mpg.de/3801127/annu...
We invite you to the “Cell Plasticity in Cancer Evolution” workshop at the MPI Evolutionary Biology, May 19–22, 2025! Join international experts who will share insights on cell plasticity in cancer and the latest research and therapies.
Registration: workshops.evolbio.mpg.de/event/123/ov...
ABC, NBC & CBS dedicated about 16 minutes of airtime last night to the California wildfires without once mentioning climate change.
Since the news failed do it's job, here's a short summary of the role of climate change and wildfire risk:
www.noaa.gov/noaa-wildfir...
New #BulletinMathBio paper by Qianci Yang, Arne Traulsen, and @evolsci.bsky.social on Integration of Immune Cell-Target Cell Conjugate Dynamics Changes the Time Scale of Immune Control of Cancer.
link.springer.com/article/10.1...
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Slide on financial toxicity of cancer care
Staggering statistics at #ASH24 #TreatingFairly
Patients with cancer who go bankrupt are nearly 80% more likely to die regardless of disease status.
Our system quite literally kills people.
The deep goal of bluesky is to decentralize the social internet so that every individual controls their experience of it rather than having it be controlled by 5 random billionaires. Everyone thinks they signed up for a demuskified twitter...we actually signed an exciting and bizarre experiment.
It uses C++ under the hood for the heavy lifting, making it quite fast.
This version includes new features, bug fixes, and improved documentation: graph-tool.skewed.de/static/doc/
Did you know that you can infer network from dynamics using graph-tool? graph-tool.skewed.de/static/doc/d... 2/N
If you are attending @evomg-bcn.bsky.social or are at the @crg.eu or in Barcelona I’ll be giving the closing keynote at 11:30am on some of our on going @evoltherapy.bsky.social clinical trials as well as showing how we use @mathonco.bsky.social to drive translation.
Pls share 🌟Join the IMP as a Group Leader
We are 👀 for a colleague, ready to lead a groundbreaking research program. Enjoy generous funding, outstanding facilities & a vibrant scientific community in one of the world's most livable cities @impvienna.bsky.social
👉https://tinyurl.com/impgl2025
For those of you here interested in #MathOnco (and maybe #SomaticEvolution #CancerEvolution) this is an important resource, and since it is a newsletter you can keep up to date with the field whether you are here or twitter (or any other site):
thisweekmathonco.substack.com
As a computational social scientist I could not miss to follow this beautiful creature: the BlueSky social network during its growth in the last hours!
In this video I show just a snapshot for about 210k users and their 500k-ish connections #academicsky
Zoom in the next post
youtu.be/JcmYZtWGnjQ
1/3 🌍 We're hiring! The Medical Systems Biology Lab at Kiel University is looking for a passionate #PostDoc in #Metabolic #Microbiome #Modeling. Join us at one of Europe’s microbiome research hubs and push the boundaries of microbiome science! @kieluni @UKSH_KI_HL
🔗 jobs.uksh.de/job/Kiel-Pos...
Now that elife is losing its impact factor, many suggest that changing the system moving away from if may take a generation.
Why should that be so? All hiring, promotion and grant committees are scientists.
A few days ago, the entire scientific community leaving X also seemed unlikely!
Along the way I began to understand the flipside, the underbelly of the world I thought I knew.
I saw where the seemingly simple materials we all rely on actually COME FROM. I saw how they’re transformed into things like silicon chips and batteries.
And I realised something else:
We invite you to the “Cell Plasticity in Cancer Evolution” workshop at the MPI Evolutionary Biology, May 19–22, 2025! Join international experts who will share insights on cell plasticity in cancer and the latest research and therapies.
Registration: workshops.evolbio.mpg.de/event/123/ov...
A starter pack for researchers interested in #ComplexSystems. Complex system science investigates how interactions among multiple parts lead to collective behaviour, as well as how the system interacts and forms links with its environment - please add your name!
go.bsky.app/FNYZ61y
