IICD is pleased to host Dr. Andrea Sottoriva from @humantechnopole.bsky.social for the next event in our Seminar Series.

Register > bit.ly/4aJsMys

#MachineLearning #PopulationGenetics #CancerEvolution #CancerResearch @columbiacancer.bsky.social @nygenome.org

📢 Early-career cancer researchers! Save $250 on registration for Spotlight on the Cancer Cell by Nov 25 (11:59pm MST). Hear from co-organizer Anwesha Dey 🎥 youtu.be/npXedgJvk5Q

Register: keysym.us/KSCancerCell26

#KSCancerCell26 #cancercell #tumorcell #cancerevolution #tumorevolution

Excited about today’s @crc1430.bsky.social @unidue.bsky.social talk by Roland Schwarz from the ICCB Cologne, hosted jointly with WTZ!
He will present on: "Inferring clonal evolution in chromosomally unstable tumours."
#ComputationalBiology #CancerGenomics #CancerEvolution

Great didactic at #MathOnco25 by @dwodarz.bsky.social showing the importance of space...and turnover in #cancerevolution

Fluctuating DNA methylation tracks cancer evolution at clinical scale. #DNAmethylation #CancerEvolution #Genomics @nature.com
www.nature.com/articles/s41...

New Group Leader Recruitment Now Open (MI/25/54) | Cancer Research UK Manchester Institute We are seeking to appoint exceptional early-career scientists, including clinician scientists, as Group Leaders to develop bold, innovative, and high-impact research programmes.

We welcome applicants with expertise in the #biology of #SolidCancers, #TumourImmunology, #CancerEvolution, & computational/ #ML approaches to #tumour ecosystems; but we encourage visionary proposals from across the spectrum of #CancerResearch that complement & expand our existing strengths

#CanSky

Evolutionary foundations for cancer biology New applications of evolutionary biology are transforming our understanding of cancer. The articles in this special issue provide many specific examples, such as microorganisms inducing cancers, the ....

Why do we get cancer?
It’s not just bad luck—it’s evolution.
This special issue explores how evolutionary biology is reshaping our understanding of cancer: why it exists, how it grows, and what we can do about it.
onlinelibrary.wiley.com/doi/full/10....
#CancerEvolution #Oncology

Life history trade-offs in cancer evolution - Nature Reviews Cancer Evolutionary life history theory posits that some organisms reproduce rapidly whereas others invest more resources in survival. This framework might help us to understand the diversity of phenotypes t...

What if tumors evolve like ecosystems?
We applied life history theory to cancer to explain why tumor cells show such diverse behaviors—from rapid growth to quiet dormancy.
#CancerEvolution #LifeHistoryTheory
www.nature.com/articles/nrc...

Longitudinal and multisite sampling reveals mutational and copy number evolution in tumors during metastatic dissemination - Nature Genetics A pan-cancer analysis of genomic data from matched primary and metastatic tumors from 3,732 patients shows that increased genomic complexity and alterations that facilitate immune evasion are associat...

This is pretty cool! Turns out genome doubling occurs in one third of metastatic cancers!

Seems that during metastasis cancer cells tend to evolve by maximizing CNAs, while not generating too many mutations that could potentially stimulate an immune response.
#cancerEvolution

Not all tumors evolve the same way.
Our paper proposes a new framework to classify tumors based on how they evolve and the ecosystems they are embedded in. Say hello to the Evo-Eco Index!
www.nature.com/articles/nrc...
#CancerEvolution #Oncology #PrecisionMedicine

13/n This was a dream postdoc project — the kind that kept me up late, but lit me up inside.
I grew immensely as a scientist, piecing together fragments of cancer evolution and immune microenvironment. Proud to share what we uncovered
#postdoclife #cancerevolution #GynOncol

Massive thanks to the two brilliant outgoing co-chairs of #CEWG @jeffreytownsend.bsky.social and Anna Barker. Thanks for all you’ve done for the field of #CancerEvolution #AACR25 @theaacr.bsky.social

Application deadline for our @wellcometrust.bsky.social #CancerEvolution summer school is tomorrow, 1 April 2025.

coursesandconferences.wellcomeconnectingscience.org/event/evolut...

Our brilliant faculty will cover evo&eco theory, math models, genomics, digital path, clinical trial design & more

We are recruiting a postdoc to join our team (myself, Boris Bastian, and Iwei Yeh) at UCSF to develop a pre-cancer atlas of skin cancer -- part of the Human Tumor Atlas Network (#HTAN). #CancerEvolution #Bioinformatics. Interested? Email resume and cover letter to me.

For those of you here interested in #MathOnco (and maybe #SomaticEvolution #CancerEvolution) this is an important resource, and since it is a newsletter you can keep up to date with the field whether you are here or twitter (or any other site):

https://thisweekmathonco.substack.com/

This week in Mathematical Oncology | Jeffrey West | Substack "This week in Mathematical Oncology" -- the weekly email newsletter. Click to read This week in Mathematical Oncology, by Jeffrey West, a Substack publication with thousands of subscribers.

For those of you here interested in #MathOnco (and maybe #SomaticEvolution #CancerEvolution) this is an important resource, and since it is a newsletter you can keep up to date with the field whether you are here or twitter (or any other site):
thisweekmathonco.substack.com

Long deletion signatures in repetitive genomic regions track somatic evolution and enable sensitive detection of microsatellite instability Deficiency in the mismatch repair system (MMRd) causes microsatellite instability (MSI) in cancers and determines eligibility for immunotherapy. Here, we show that MMRd tumours harbour long-deletion s...

Thrilled to share our discovery of novel long-deletion signatures—key markers for tracking #MMRd #CancerEvolution, even in low-pass (~0.1X) FFPE samples with low purity. This was made possible with our tool, MILO, as named by @trevorgraham.bsky.social. Our preprint: www.biorxiv.org/content/10.1...

What a week at the Field's discussing #MathOnco and #CancerEvolution / #CancerEcology. Thanks Jasmine Foo and Dominik Wodarz for organizing! and Thomas Hillen too!

Mathematical Biosciences | Journal | ScienceDirect.com by ElsevierScienceDirect Read the latest articles of Mathematical Biosciences at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature

Happy to join Mathematical Biosciences as an editorial board member. I am hoping to bring my expertise in #AgentBasedModels and #EvolutionaryGameTheory to model #CancerEvolution and #TreatmentResistance in the context of #Ecology
www.sciencedirect.com/journal/math...

AACR Special Conference in Cancer Research: Translating Cancer Evolution and Data Science: The Next ... In association with the Cancer Evolution Working Group December 3-6, 2023Westin Copley PlaceBoston, Massachusetts Conference cochairs Anna D. Barker, Ellison Institute for Transformative Medicine of U...

Planning my trip to #AACRevol23 #CancerEvolution in Boston next month, who else is coming?
www.aacr.org/meeting/aacr...

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Tired of the #NeurIPS grind? Come see me speak about #cancerevolution at @VanBUG_ this Thursday at 6pm http://www.vanbug.org/2019/quaid-morris-2/ BC cancer agency isn’t THAT far away, you should see more of Vancouver!

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Tired of the #NeurIPS grind? Come see me speak about #cancerevolution at @VanBUG_ this Thursday at 6pm http://www.vanbug.org/2019/quaid-morris-2/ BC cancer agency isn’t THAT far away, you should see more of Vancouver!