I am so excited to share our new findings with you! We provide the structural evidence for a direct protein-to-DNA information pathway, showing how a bacterial enzyme 'reads' its own structure to 'write' DNA. www.science.org/doi/10.1126/...
CRG members with Dr. Upeksha Dissanayake
Newly minted Dr. Upeksha Dissanayake and GAC
Congratulations to Dr. Upeksha Dissanayake @upeksha.bsky.social on a fantastic defense!
Upeksha is the 16th PhD from our group
"these attacks were designed to set up the Trump administration to act with impunity. [They] laid the groundwork ...[to] make decisions based on ideology rather than evidence; remove staff, scientific findings, & regulations that could have been roadblocks to its agenda" blog.ucs.org/jules-barbat...
Alice Walker presenting at ACS spring 2026
@arwalker.bsky.social Alice Walker crushing it at #ACSSpring2026
Symposium in honor of Prof. Weitao Yang
Symposium in honor of Prof. Weitao Yang
Symposium in honor of Prof. Weitao Yang
First talk of the first session of the symposium celebrating the 65th birthday of Prof. Weitao Yang
#ACSSpring2026
Nowruz Mubarak Lynn!
Congrats Kresten, very well deserved!
Another excellent Substack from Elizabeth Ginexi on a near-stoppage of release of Notices of Funding Opportunity (NOFOs) at NIH and why it matters
open.substack.com/pub/elizabet...
How do pairs of DNA loci - such as enhancers and promoters - find each other inside the nucleus? 🤔
Most models assume the random forces driving locus motion are independent in space
New preprint by
@janniharju.bsky.social: this assumption fails in living cells 🧵
www.biorxiv.org/content/10.6...
Latest preprint, great collaboration with Deyu Li and Evans Boateng, with contributions from Shubham Chatterjee @shubhamchatterjee.bsky.social and Jose Madriaga on the kinetic and mechanistic analysis of AlkB:
A well-played meme by Jeremy Berg in response to Stuart Buck and Aishwarya Khanduja on their R&D funding piece : goodscience.substack.com/p/a-reality-based-view-o...
Prof. R. Hernandez speaking to UTD-ACS and UTD-SACNAS students
Prof. Hernandez and comp/theory students
Always an honor and a pleasure to host JHU Prof and @acs.org president Dr. R. Hernandez.
Thanks for the fascinating science and all advice and wisdom shared.
¡Gracias Rigoberto!
Waiting to see how long it takes institutions reinstate the diversity, equity, and inclusion programs they shut down, re-hire those they pushed out, and rewrite all the language they rushed to change.
Something tells me it'll likely be a long wait.
A small polymerase ribozyme that can synthesize itself and its complementary strand | Science www.science.org/doi/10.1126/... - this looks super cool, but does it really relate to the origin of life?
Freeman Hrabowski III, the President Emeritus from the University of Maryland Baltimore County, giving a TED talk.
This is a powerful message from Freeman Hrabowski.
🧵
1/12
🚨 Epstein survivors release this powerful PSA in advance of the Super Bowl demanding answers from the Justice Department. This is the Super Bowl ad every American should see. Spread it everywhere.
Meyerson stage, chandelier and little prince program
Full cast
Opening night of the Dallas Opera’s production of The Little Prince with the Greater Dallas Choral Society (GDCS)
Really enjoying Colbert's final season of "fuck it, we're going down swinging" tour.
A reminder that proteins are highly dynamic molecules.
🟧 We have made much progress in measuring & predicting static protein structures, but the dynamics that animate life remain challenging to measure & model.
This video warrants reposting again & again. ICE is not slowing down in MN. They’re just changing tactics that you must be aware of.
Please, please listen and pass this on.
#StandTogether #Pinks #ProudBlue #OneV1
I wrote this song on Saturday, recorded it yesterday and released it to you today in response to the state terror being visited on the city of Minneapolis. It’s dedicated to the people of Minneapolis, our innocent immigrant neighbors and in memory of Alex Pretti and Renee Good.
Stay free
Vibrant color portrait of Jane S. Richardson, the visionary biophysicist and artist who revolutionized structural biology with her invention of ribbon diagrams. She gazes warmly at the camera with a bright, knowing smile that radiates quiet brilliance and decades of curiosity. Her silver-blonde hair woven with gentle waves. Large, elegant dangling earrings catch the light, and she wears a richly patterned brown blouse embroidered with intricate turquoise paisley motifs and delicate beadwork that echoes the molecular elegance she has spent her life depicting. Behind her floats a luminous, dreamlike backdrop of glowing molecular structures--interlocking hexagonal and ribbon-like forms in electric blues, teals, and greens--blending science and art in a single, living canvas.
Hand-drawn and hand-colored (by Jane Richardson) scientific artwork known as a Richardson ribbon diagram (or “ribbon model”), one of the iconic visual inventions of Jane Richardson that transformed the way we see and understand protein structures. A graceful, three-dimensional tangle of protein backbone ribbons twists and spirals through space, rendered in soft pencil lines and luminous watercolor hues. Smooth golden-brown coils represent α-helices that curl like elegant ribbons, while broad teal-green arrows trace the flat, pleated strands of β-sheets slicing through the molecule with directional purpose. Thin, looping golden threads connect the secondary structures, creating a delicate, almost dance-like choreography of biology’s hidden architecture. The entire form is framed by a simple olive-green mat and dark border, giving the drawing the quiet dignity of both fine art and precise scientific illustration—a timeless bridge between molecular reality and human imagination.
Jane Richardson was born #OTD in 1941
+ Developed the Richardson (ribbon) diagram to represent proteins' 3D structure (becoming a standard representation for protein structures)
+ MacArthur Fellow, 1985
+ Elected, Nat'l Academy of Sciences, 1991
+ President, Biophysical Society, 2012
#WomenInSTEM
The Senate may choose to vote together on the DHS and LHHS bills. Thus, a filibuster on DHS may mean no funding for NIH. What my colleagues are saying:
“Shut it down, public health will understand. I’ll work without pay again.”
- anonymous NIHer
Particularly of interest to people who want to do protein design in an academic environment w/ many colleagues in basic science (cancer biology, cell signaling, immunology, virology) & clinicians who can drive the discovery of new targets for hard-to-treat diseases & bring therapeutics to patients.
A person holding out their arm while people line up on it. The hedline is: One mentor isn’t enough. Here’s how I built a network of mentors
"One email at a time, one informational interview after another, I became comfortable, confident, and strategic in building my network of mentors."
One mentor isn’t enough, wrote Erika Moore in this 2021 Working Life essay. https://scim.ag/3Zfm0e8 #NationalMentoringMonth
The Matilda Effect: what an infuriating but all too familiar narrative of credit for discoveries owed to women in science being *stolen* by male colleagues who then go on to reap the recognition/profits from it and behave so appallingly.
![Green Day - American Idiot [Official Music Video] [4K Upgrade]](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:5lyuap7upaxgmgrrlkzfrof7/bafkreign3vpeceg6gb52a6sjdudbj52jabaxpksvk2ogbo5vbch7wu26om)
www.youtube.com/watch?v=Ee_u...
