21st century dev bio at its best! I can't help but point out that not one but two Bruker microscopes (Acquifer IM, MuVi) were used for gentle&long term time lapse imaging of developing Nematostella here. No need to mount your invertebrate (cnidaria, planaria, crustaceans), we can do the time lapse!
Now published. Congrats to Soham and all co-authors! www.science.org/doi/10.1126/....
@embl.org
Congratulations Guillaume #Salbreux and collaborator @aikmi.bsky.social groups for your latest publication in @cellcellpress.bsky.social: Deciphering #mechanical determinants of morphological #evolution @genevunige.bsky.social @sciencesunige.bsky.social #UNIGE
👉 www.cell.com/cell/fulltex...
Thanks, Elias!
Gracias, hermano!
A press release on our latest work on shape diversity in cnidarians. @embl.org
Hello epithelia enthusiasts!
I’m @inesfournon.bsky.social and I study epithelial mechanics in sea anemones 🪼
Did you know epithelial cell extrusion had never been described outside bilaterian animals before? Well… not anymore 👀
Read ⬇️🧵1/9
Evolution of monoamine reception and its role in cellular contractility.
How do #sponges coordinate their bodies despite lacking neurons and true muscles?
We show that sponges use monoamines to control water flow in their canals — reminiscent of how adrenaline regulates blood vessels.
My PhD story, now on BioRxiv:
www.biorxiv.org/content/10.6...
#Evolution
Credit: Mylan Ansel
Expansion microscopy of a loricate choanoflagellate, generated by Mylan Ansel in our lab 🤩
(yes, the lorica expands. No, we don't understand how either)
We’re looking for a new team member! 🚀
Only 3 more weeks to apply to the fantastic Vienna BioCenter PhD program
Thanks, Suhrid!
🔥Exciting new paper from the Ikmi group @embl.org! The authors identified a set of mesoscale mechanical modules that can be used to predict species-specific shapes by combining a comparative analysis of cnidarian larval morphogenesis with active surface theory #morphogenesis #cnidaria
Thanks, Vlad!
Amazing to see this study finally out! Proud to have contributed to the active surface modelling of cnidaria morphogenesis across species and huge congrats to Richard, Nicolas, and all authors! #morphogenesis #activematter #nematicorder #evolution
Thanks, Arnaud!
Our study on shape diversity in cnidarians is now published. The final version includes extensive new data that substantially extend the original bioRxiv preprint. Congrats to everyone who contributed to this work! www.cell.com/cell/fulltex...
@embl.org
New Preprint! When one enhancer allele changes another's regulatory output, is that bad? We found it could be a feature — interallelic cis-regulatory dominance buffers outputs AND enables evolutionary innovation. Two for one!
Led by @ottilie.bsky.social from @embl.org
doi: doi.org/10.64898/202...
It's out! Happy to present ITEC, a semi supervised algorithm with an extremely low error rate that can track cells in files of any size (think Terabytes!). We used it in many organisms, including zebrafish, to study how organs form and linked it to gene expression www.biorxiv.org/content/10.6... +🧪
Cool! Phenotyping a land planarian begins.
Our paper on the role of neurons in Nematostella head regeneration is now out at @currentbiology.bsky.social Big thank you to all collaborators, it was a pleasure!
Ectopic head regeneration after nervous system ablation in a sea anemone: Current Biology www.cell.com/current-biol...
Only a few days left for abstract submission at the brand new EMBO|EMBL Symposium Collectivity in living systems: emergence, function and evolution. We have stellar speakers in cell, animal collectives & beyond @priscaliberali.bsky.social @icouzin.bsky.social @ricardsole.bsky.social
Join us!
Our Special Issue on Lifelong Development #LifelongDevSI is now complete!
Guest edited by Meri Huch and Mansi Srivastava, it contains 26 research and review-type articles.
On the cover: the dorsal vasculature of an adult zebrafish's first gill arch. See Preußner et al. doi.org/10.1242/dev....
Also in #LifelongDevSI :
▪️Editorial
▪️Hypothesis on phenotypic plasticity
▪️2 interviews with our guest editors
▪️3 Reviews
▪️17 Research Articles and Reports
▪️3 Techniques and Resources
Full table of content: journals.biologists.com/dev/issue/15...
Great having you at @embl.org, Michel! Inspiring science, great discussions, and a fantastic perspective on quantitative evo-devo.
Had the pleasure of working with @mohannad-dardiry.bsky.social to rethink what it means to develop for life. Many thanks to @dev-journal.bsky.social! @embl.org #LifelongDevSI
Latest from ours: www.cell.com/cell-reports...
This is two stories in one: a case study/cautionary tale on developing genetic tools in new organisms, and the first hint at a gene regulatory network for choanoflagellate multicellular development (which turn out to involve a Hippo/YAP/ECM loop!) A 🧵
Finally, the excellent postdoc work of Emmanuel Haillot is out, where he dissected the integration of Wnt, MAPK and Notch signaling in defining mesoderm and endoderm identities in the diploblast Nematostella. Strikingly similar to sea urchins. www.nature.com/articles/s41...
Want to help us image and understand those incredible samples Felix just collected at UBC - and many more?
2 more days to apply!
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
#ExM #PlanetaryCellBiology
🧪🧬🔬🌍🌱🦠
