New work from Maryanne Barasa et al shows that CX3CR1 deletion results in delayed microglial engagement and clearance of dying cortical neurons! 2Phatal continues to help us uncover important cell-cell interactions in vivo.
www.biorxiv.org/content/10.6...

Flexible ensheathment of axons enables myelination of complex CNS networks - Nature The rate of axon ensheathment varies within individual myelinating processes, resulting in chains of myelin sheaths connected by bridges consisting of thin cytoplasmic processes that provide&nbsp...

Latest offering. How myelin ensheathes axons!

Born from chat with Dwight Bergles on "weird things" we saw oligodendrocytes do, like making "bridges" between sheaths.

Driven forward by Cody Call, Kelly Monk, and myelin folks @edinburgh-uni.bsky.social

Enjoy!
www.nature.com/articles/s41...

JCI - Disruption of CSF-1 receptor-mediated metal ion homeostasis in the murine brain promotes neurodegenerative disease www.jci.org/articles/vie...

The Human Microglia Atlas (HuMicA) unravels changes in disease-associated microglia subsets across neurodegenerative conditions - Nature Communications The Human Microglia Atlas includes 91,716 brain immune cells covering six neurologic pathologies. It characterizes the signatures of nine populations and describes the expansion of GPNMB-high microgli...

🚨 Respurce alert: Human Microglia Atlas (HuMicA) unravels changes in disease-associated microglia subsets across neurodegenerative conditions

Antidepressants promote developmental-like plasticity through remodeling of extracellular matrix www.biorxiv.org/content/10.1101/2025.01....

I'm pleased to see that established researchers like myself are "not" eligible to apply for this grant opportunity🤩.
I firmly believe that the majority of foundation grants should be invested in junior investigators.

Astrocyte-derived extracellular matrix proteins regulate synapse remodeling in stress-induced depression Major depressive disorder (MDD) is a common mood condition affecting multiple brain regions and cell types. Changes in astrocyte function contribute to depressive-like behaviors. However, while neuron...

One last paper to share in 2024 🧪 glad to have contributed to this one during my time at Mount Sinai 🤓👩‍🔬
🧠 #Astrocytes extracellular matrix #stress #depression #synapse remodeling

www.biorxiv.org/content/10.1...

❗️🆕️❗️Distinct transcriptional changes distinguish efficient and poor remyelination in multiple sclerosis 

academic.oup.com/brain/advanc...

🗞️🚨 OPCs news 🤩!!
#glia #opc #glucocorticoids #stress

www.biorxiv.org/content/10.1...

Oligodendroglia starter pack!

Missing many, please share and comment below to be added. Go team Oligo 🧠🦋!

go.bsky.app/JgL2evN

Neuroscientists! A key message from the ALBA Network
Please help us spread the word and share this with your network!!!
Nominate (self-n allowed) a mid-career neuroscientist (5+ years post-PhD) for the ALBA-Roche Research Prize for Excellence in Neuroscience!
🔎http://loom.ly/_EvQvm4
🗓️20 January 2025