Advertisement ยท 728 ร— 90

Posts by Michael P Hart ๐Ÿณ๏ธโ€๐ŸŒˆ (he/him)

Post image

Please join us in celebrating the life and legacy of Assoc. Prof. Laura Grafe, and the dedication of the Dr. Laura Grafe Endowed Student Research Fund.

Sunday April 19th, 2026
2:00 - 4:00 pm
Bryn Mawr College

lnkd.in/ehM3jxDD]
To contribute to the Dr. Laura Grafe Endowed Fund for Student Research

2 weeks ago 4 2 0 0

Beautiful work!!

2 months ago 1 0 0 0
Post image Post image Post image

@tdrivas.bsky.social

3 months ago 4 0 0 0
Video

2025 wasโ€ฆ something. But time closing it out on the slopes with family has me smiling and optimistic for 2026!

3 months ago 2 0 1 0
Preview
Natural variation in Caenorhabditis elegans collective behavior reveals potential adaptation to novel environments Recent advances in quantitative approaches to behavior have enabled rigorous trait measurements that allow us to understand how behavior evolves in multiple taxa([1][1]โ€“[7][2]). However, placing these...

And together with work from Serena Ding on variation of the behavior in wild C elegans isolate strains, completes a survey of social feeding in our favorite nematodes! www.biorxiv.org/content/10.1...

5 months ago 2 0 0 0
Preview
Conserved autism-associated genes tune social feeding behavior in C. elegans Nature Communications - C. elegans aggregate in large clumps during feeding. Here, the authors find conserved autism-associated genes mediate distinct molecular and circuit signaling components...

This new work gives broader context for @maracowen.bsky.social's paper on social feeding and conserved autism genes in C. elegans!
rdcu.be/eQMoB

5 months ago 3 0 1 0
Preview
Variation in Social Feeding Behaviors and Interactions Among Caenorhabditis Nematodes Different species of roundworms (nematodes) are frequently found together in the wild and can aggregate in groups while feeding. We find that different species of worms display a range of feeding beh...

A fun evolution and behavior project initiated by a summer undergrad Reina Eugene (PGSIP intern!) with Dustin Haskell - Variation in Social Feeding Behaviors and Interactions Among Caenorhabditis Nematodes @penngenetics.bsky.social @ecol-evol.bsky.social onlinelibrary.wiley.com/doi/10.1002/...

5 months ago 14 2 2 0

Amazing!! Should blow it up and frame it!!

5 months ago 2 0 0 0
Advertisement
Post image

In the October issue of #GENETICS, @michaelphart1.bsky.social and colleagues report #Celegans mutant analysis that identified conserved #autism genes with functions in experience-dependent neuron remodeling and circuit plasticity. buff.ly/ZrxH4rM

5 months ago 4 1 0 0
Post image

In #GENETICS, @michaelphart1.bsky.social and colleagues performed a mutant screen in #Celegans to identify conserved #autism genes with functions in experience-dependent neuron remodeling and circuit plasticity. buff.ly/f5UYogl

6 months ago 4 3 0 0
Preview
CAJAL enables analysis and integration of single-cell morphological data using metric geometry - Nature Communications Cell morphology is one of the most described phenotypes in biology, yet systematic quantification and classification of morphology remains limited. Here, the authors present a computational approach f...

Also thrilled to continue an awesome collaboration with
@camarapg.bsky.social (@penngenetics.bsky.social) using the #CAJAL algorithm to analyze >1000 DVB neuron reconstructions from the screen!! (original CAJAL paper = doi.org/10.1038/s41467-023-39424-2)

8 months ago 2 0 0 0

Stay tuned for follow-up mechanistic work exploring H4K20 methylation as a regulator of neuron remodeling involving set-4 (KMT5B), and a bunch of conserved synaptic genes!!

8 months ago 1 0 1 0
Preview
Multiple autism genes influence GABA neuron remodeling via distinct developmental trajectories Abstract. Variation in over 100 genes are now associated with increased risk for autism and related neurodevelopmental conditions, but how this variation r

Do you like neuronal #plasticity? #genetics? #Celegans? Check out 1st installment of work by Kristi Zoga in the lab. Kristi screened 20 conserved #autism genes for roles in experience-dependent #neuron remodeling and a related behavior.
doi.org/10.1093/genetics/iyaf156

8 months ago 30 7 3 1

Awesome, excited to see it @ethanewe.bsky.social !!

8 months ago 1 0 1 0

This all checks out. As a donor, the endless fundraising texts and emails I receive after donating make me donate LESS!!! Figure out a better way to not piss off unit supporters @housedemocrats.bsky.social

8 months ago 2 0 0 0

๐Ÿ”— Check out the full paper:
www.cell.com/ajhg/fulltex...

๐Ÿ“ข Read the Science coverage:
www.science.org/content/arti...

๐Ÿ’™ Excited to keep pushing this conversation forward!

9 months ago 2 0 0 0

Feature article on latest work from @tdrivas.bsky.social Genetic testing of critically ill adults yields surprisesโ€”and reveals disparities in treatment of Black patients | Science www.science.org/content/arti...

9 months ago 5 1 1 0
Advertisement
Video

We're asking YOU to run for office and we're partnering with the best of the best to make it happen: Pipeline Fund, LEAD NC, Annie's List, Texas Leadership Pipeline, Instituto, Run for Something, and National Democratic Training Committee.

Learn more at votesaveamerica.com/run

9 months ago 104 32 10 1
Preview
SCIMaP - Impacts of Federal Cuts to Science and Medical Research Developed by an interdisciplinary research team, this website shows how funding cuts reduce economic activity and employment nationwide

The White House's proposed FY26 budget would cut NIH funding by >40%. Our new #SCIMaP report projects the budget would lead to economic losses throughout the US with $10M+ lost in almost every House district.
scienceimpacts.org/fy26

@joshuasweitz.bsky.social @asinclair.bsky.social @cl10.bsky.social

9 months ago 99 66 4 4

(5/5)

๐Ÿšจ Itโ€™s time to flood the zone.

NIH scientists just took a huge risk speaking out. Now itโ€™s our turn.

๐Ÿ“œ Read the Bethesda Declaration
โœ๏ธ Sign the Public Letter of Support
๐Ÿ‘ฏโ€โ™€๏ธFollow NIHers doing the work: @nihvigils.bsky.social

Read and sign here ๐Ÿ‘‰ www.standupforscience.net/bethesda-dec...

10 months ago 455 252 3 33

"Women are PIs on 58% of the canceled grants, although they are PIs on only 34% of all active NSF grants.

Similarly, Blacks are PIs on 17% of the terminated grants, although they make only 4% of the total pool. Hispanic PIs and those with disabilities were twice as likely to lose a grant."

11 months ago 1290 944 31 63
Post image Post image Post image Post image

Devastated by the loss of my amazing friend and colleague Laura Grafe (@grafelab.bsky.social, Bryn Mawr). She was beautiful, brilliant, and bursting with life! Her love and light burned so bright, it will forever be with everyone who was lucky enough to know her. Rest In Peace @pennngg.bsky.social

11 months ago 5 1 0 0
Post image

Beyond excited to host @dacolon.bsky.social today for the Distinguished Seminar Series at @pennmedicine.bsky.social @penngenetics.bsky.social!! Come see a terrific talk at noon!

11 months ago 6 1 0 0
Preview
RFK pushes to find 'environmental' cause of autism, calls rising rates an 'epidemic' Researchers and advocates have pushed back at what they consider inaccurate and stigmatizing comments made by the health secretary, and note the causes of autism are complex.

Researchers and advocates have pushed back at what they consider inaccurate and stigmatizing comments made by the health secretary, and note the causes of autism are complex.

1 year ago 1868 396 259 68
Advertisement
Preview
RFK Jr. Calls Autism โ€˜Preventable,โ€™ Drawing Ire From Researchers The health secretary said he would prioritize studies into environmental causes while harshly discounting other factors scientists say are likely contributing to rising rates of the condition.

Ire isn't the right word... he is wrong and is stigmatizing 1 in ~40 children. 'Kennedy called research into the genetic factors in whether a child will develop autism โ€œa dead end.โ€ โ€œGenes donโ€™t cause epidemics,โ€ he said. โ€œYou need an environmental toxin.โ€" www.nytimes.com/2025/04/16/u...

1 year ago 1 0 0 0
Preview
โ€˜Treated like a criminal': US citizen says he was detained returning from Canada Bachir Atallah, a real estate attorney from New Hampshire, says he and his wife, Jessica Fakhri, were stopped crossing from Canada into Vermont

"After nearly five hours, he and his wife were released. They are now pursuing legal action.

"It's not about the immigrants," his sister, told NBC10 Boston. "It's coming to us Americans, and it's going to go after all of us."

www.nbcboston.com/news/politic...

1 year ago 27803 10601 1857 872
Post image

So excited to host @singhvilabglia.bsky.social (One of my favorite scientists to spend time with!!) tomorrow for the @pennngg.bsky.social and MINS seminar!! Come learn about glia!!

1 year ago 7 1 0 1
Preview
A genotype-first approach identifies high incidence of NF1 pathogenic variants with distinct disease associations - Nature Communications Our current understanding of neurofibromatosis type 1 (NF1) is based on patients ascertained through phenotype-first approaches, which estimate a low prevalence at 1 in 3,000. Here, the authors levera...

Patience, collaboration, and perseverance pay off! Our investigation of the population prevalence of NF1 pathogenic variants is out today in @naturecomms.bsky.social! We find these variants are much more common than anticipated and confer increased risk for cancer.

www.nature.com/articles/s41...

1 year ago 5 1 6 0
Preview
Join the C. elegans Community Mentor Match Program! Join the C. elegans Community Mentor Match Program! sign up for mentors sign up for mentees and to join peer-mentoring groups https://forms.gle/DpGTWRMrNGL96wHy8 https://forms.gle/pVBD5DYGXyLT4waLA

attention worm peeps! we need YOU to help recruit more mentees for the C. elegans Community Mentor Match program! ๐Ÿชฑ๐Ÿงช mentees of all stages are welcome to join!

Please help us sign up more mentees by sharing this this slide with your lab in your next lab meeting!

docs.google.com/presentation...

1 year ago 3 7 0 0
Post image

Amazing support for SCIENCE with so many familiar faces! (Dog, sign, and picture courtesy of @glennislogsdon.bsky.social) @tdrivas.bsky.social @korblab.bsky.social @standupforscience.bsky.social #standupforscience2025

1 year ago 14 1 0 1