🧬🖥️ 🎬 Final take: Call for Talks - German Conference on Bioinformatics (#GCB2026)
📍 Saarbrücken, Germany | 🗓 22–25 September 2026
🔗 Details & submission: gcb2026.de/Programme/Ca...
Lecture abstracts deadline: 3 May 2026
Poster abstracts deadline: 6 August 2026 (max. 150 – first come, first served!)
The next #ScienceatDKFZ event will take place on Monday, 20 April 2026, at 4 pm. In addition to the keynote lecture by Franziska Blaeschke, there will be four 5-minute short talks by DKFZ junior scientists on recent highlight publications. @blaeschkelab.bsky.social
www.dkfz.de/en/news/even...
Dreaming of a career in cancer research?
Join the International PhD Program at DKFZ - Germany’s largest biomedical research center.
Explore #cancerresearch including #cancerbiology, #bioinformatics, #epidemiology & #medicalphysics.
The Summer Selection is open now 👉 apply here: t1p.de/hl56b
Join us this summer in Frankfurt for outstanding science and a great community…….so easy to travel to, and Heidelberg is only a short train ride away if you want to visit our historic old town located on the Neckar river.
Epigenetic dysregulation of IRF9 drives excessive #interferon signaling in #COPD
By M. Llamazares-Prada, R. Jurkowska & colleagues @biomedx.bsky.social & Cardiff University
🗞️ doi.org/10.1038/s44321-026-00386-9
Ein Politiker sexualisiert Schulmädchen und die Republik greift die Frau an, die das öffentlich gemacht hat. Und ihr tut so, als würde euch Epstein schockieren. Das ist genau das Klima, das sowas überhaupt über Jahre hinweg ermöglicht hat.
The main project of my PhD 🧬🔬 is out: we developed single-cell lentiMPRA, a lentivirus-based method to measure enhancer activity and transcriptomes at single-cell resolution. We then applied sc-lentiMPRA to fully synthetic enhancers 🧩...
🔗 doi.org/10.64898/202...
Proud of @juruehle.bsky.social for getting her PhD paper on biorxiv! In it, we take synthetic enhancer screens to the single cell level, offering new insight into how transcription factors and enhancers interact 👀
Early bird registration is closing Feb 28! We will have an AMAZING party!
Una buena noticia para empezar el año 😊 El trabajo liderado por @larsplus.bsky.social, investigador del CRG, ha sido reconocido por la Asociación Española contra el Cáncer como uno de los avances de investigación más destacados de 2025.
ONLINE FIRST ALERT!
Molecular #Plasticity Results in #Oncofetal #Reprogramming and Therapeutic Vulnerabilities in Juvenile Myelomonocytic Leukemia
aacrjournals.org/bloodcancerd...
@aacrjournals.bsky.social
#childhoodcancer
#epigenetics
#precisiononcology
Do not miss this conference!
If you are thinking where to do your Postdoc, I can only give my highest recommendations to join Lars and his team!
Do you teach #rstats? Do your students complain about how lame and old-fashioned dplyr is? Don't worry: I have the solution for you: github.com/hadley/genzp....
genzplyr is dplyr, but bussin fr fr no cap.
🚀 Thinking about your next big career step in science?
The Int'l PhD Program at DKFZ could be a perfect fit for you.
🌍 Work in an international environment, with 500+ doctoral researchers
🔬 Do cutting-edge cancer research
Curious? Join our online info session on 20 Nov. Register here: t1p.de/ws7q3
This was a lot of fun! Thanks Daylon and @arunsharmaphd.bsky.social for being great hosts!
DNA-methylation-based deconvolution can be a powerful tool for identifying novel disease subgroups. In our paper in Acta Neuropathologica, we show how this can be leveraged in IDH-mutant gliomas - specifically in oligodendrogliomas.
doi.org/10.1007/s004...
#IRBBarcelona & @crg.eu scientists identify DNA “barcodes” that mark blood cell #aging—accelerating after 50. Published in @nature.com, the work could pave the way for preventive, personalized #antiaging therapies.
https://youtu.be/ST5YmqqMcuQ
@alejofraticelli.bsky.social
#AgingResearch
🧪
Ein Team aus Forschenden vom BIH, @mdc-berlin.bsky.social, DKFZ, HI-STEM und @qmul.bsky.social hat eine Technologie zur Entschlüsselung der Immunzell-Kommunikation entwickelt. Damit lässt sich unter anderem ablesen, warum Immuntherapien bei manchen Menschen wirken bei anderen nicht.
t1p.de/w3v16
Excited to share our latest paper @natmethods.nature.com
We present a high-throughput framework to map cellular interactions at ultra-high scale – broadly applicable from whole-organism immune response mapping to personalized therapy response prediction (1/4).
www.nature.com/articles/s41...
Integrative spatial and multi-omic profiling in bladder cancer links L1 retrotransposition to extrachromosomal DNA, genomic instability, and viral mimicry response www.biorxiv.org/content/10.1101/2025.07....
Do you want to improve our understanding of therapy resistance induced by epigenetic heterogeneity? Do you have a PhD in Molecular Biology or related fields? Join us as a (fully-funded) Postdoc in the Division of Cancer Epigenomics at DKFZ. More information here: www.dkfz.de/en/cancer-ep...
In our study published in Leukemia, we showed that HMA treatment can also lead to repression of oncogenes such as MNX1 through the activation of miRNAs. Great work by Simge Kelekci from our division. www.nature.com/articles/s41...
Out in Leukemia (@natureportfolio.nature.com). Hypomethylating agents (HMAs) such as decitabine are used in clinical practice for the treatment of Acute Myeloid Leukemia and expected to re-activate tumor suppressor genes de-activated by aberrant DNA methylation.
The next #ScienceatDKFZ event will take place on Monday, 23 June 2025, at 4 pm. In addition to the keynote lecture by Chong Sun, there will be four 5-minute short talks by DKFZ junior scientists on recent highlight publications.
➡️ dkfz.de/en/news/even...
Stunning @nature.com paper from the labs of our great friends @larsplus.bsky.social and @alejofraticelli.bsky.social on modelling somatic epimutations for transgene-free single-cell clonal tracing in blood ageing! Enjoy the read: doi.org/10.1038/s415... 🧪
1 plant hormone receptor ☘️
3,500 mutants, to single-site saturation 🧬
>45,000 binding and abundance measurements 📶
Very happy to present our latest work – where deep mutational scanning meets the world of small molecules.
www.biorxiv.org/content/10.1...
With @benlehner.bsky.social
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Thanks to phenomenal work by @crg.eu and @irbbarcelona.org press offices, we got to communicate our findings on 🧬 methylation barcodes and 🩸 blood ageing to a wide audience. A cool experience!
🧵 with highlights in 5 languages and funny moments 😬😅
cadenaser.com/nacional/202... (1/n)
