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Posts by Matt Johnson β„οΈπŸ”¬πŸ¦ 

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Last week we had the CCeMMP Symposium 2025. Fantastic event with an outstanding line-up of speakers. There were 2 poster prizes and 1 oral presentation prize; thrilled that we did a clean sweep! Huge congratulations @tiltedscientist.bsky.social @somavallyd.bsky.social and @lucatroman.bsky.social

5 months ago 7 3 0 1
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A Protein Antibiotic Inhibits the BAM Complex to Kill Without Cell Entry Many antibiotics are ineffective against Gram-negative pathogens such as Pseudomonas aeruginosa because they cannot penetrate the bacterial outer membrane. Here, we show that protein antibiotics calle...

The outer membrane of Gram-negative bacteria blocks many antibiotics. Our latest work reveals that L-type pyocins bypass this barrier by inactivating the BAM complex, killing Pseudomonas aeruginosa without entering the cell, providing a new blueprint for beating antibiotic resistance.

7 months ago 70 37 1 4
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Tiny Tubes Reveal Clues to the Evolution of Complex Life | Quanta Magazine Scientists have identified tubulin structures in primitive Asgard archea that may have been the precursor of our own cellular skeletons.

Story on our Asgard microtubule paper by Nikki Greenwood: www.quantamagazine.org/tiny-tubes-r...
Thanks to all interviewees🎀

7 months ago 36 13 0 0
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We recently discovered a brand-new (and unique!) anti-phage defense system in bacteria. Check out this Pursuit article from @Melbourne University featuring our recent work. Terrific effort from our PhD student Somavally!

lnkd.in/geXUApmK

7 months ago 8 2 1 1

We are excited to share our new study which talks about the unique anti-phage system. Please check out the article for more details. Thank you Debnath Ghosal and Sigal Ben Yehuda for this amazing opportunity. Thank you University of Melbourne and Pursuit team!

7 months ago 1 1 0 0
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πŸ“£ New paper alert! Just out in Cell Reports! pubmed.ncbi.nlm.nih.gov/40644298/
Thrilled to share that we have discovered a brand-new anti-phage defense system! Bacteria have evolved various defense strategies (CRISPR etc) to counter phage attacks. We found a new one - fascinating and dramatic
βš”οΈπŸ¦ β„οΈπŸ”¬

8 months ago 151 53 3 5

An Asgard archaeon from a modern analog of ancient microbial mats www.biorxiv.org/content/10.1101/2025.07....

8 months ago 5 1 0 0
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Excited to share that our work on a family of pore-forming proteins is now live in Science Advances! We show structural snapshots across the entire pore-forming pathway for a cholesterol-dependent cytolysin-like (CDCL) bicomponent system.

1 year ago 32 9 3 0

Fabulous collaboration with Steve Petrovski lab at La Trobe University. Amazing team that made this happen @tiltedscientist.bsky.social, JaysonRose, MiladReyhani, @unimelb, @FMDHS, @ccemmp-outreach.bsky.social.

1 year ago 3 2 1 0
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Delighted to share our recent work in Nat Comms. This is a "Story of a dwarf predator"
www.nature.com/articles/s41...

1 year ago 21 6 1 0

I am very happy to announce that we solved the in-virus #cryoEM structure of the #HIV matrix protein. The structure helped us to resolve a long mystery in HIV biology. A🧡1/5
Read more in Nature: www.nature.com/articles/s41... πŸ§ͺ

1 year ago 238 42 10 5

Oh this is me, hello bsky!

1 year ago 2 0 0 0

Please add me to your list. Thank you for doing this.

1 year ago 0 0 1 0