After the poster, the presentation ! #FOM2026

Mathieu (proudly) representing the BIC #FOM2026. It's happening now !

Yesterday, the 4 teams of the BIC spent a very nice moment together. We had presentations from the newest members of the BIC (and not so newest), and a shared lunch on the sunny terasse of the INRAE campus !

This week, engineers from the photonics division are leading the longest-running course in our catalog: The Basics of Wide-Field and Confocal Microscopy !

[EVENT] Registrations are now open for the SFBS-2026

Join us in Bordeaux (Oct 14–21, 2026) for an advanced workshop and an international symposium

📆Workshop application deadline: May, 1
📆Symposium early bird registration deadline: June, 15

More info👉 france-bioimaging.org/news-events/...

This week @jeremie-bic.bsky.social presented his work on sample clearing and light-sheet imaging during @france-bioimaging.bsky.social annual meeting. This is the pure définition of the "Whaou" effect! Congrats !!!

Meeting annuel @france-bioimaging.bsky.social à #Rouen Attention !! @jeremie-bic.bsky.social @bic-bordeaux.bsky.social est dans la place !

#clearing
#brain

Interested in plant biology and super-resolution microscopy? This EMBL workshop is for you! You will learn how efficient tau-STED Xtend is in Arabidopsis root tip.
With Christel Poujol @bic-bordeaux.bsky.social and Magali Grison from our Lab, register before April 6th!

www.embl.org/about/info/c...

#ImageOfTheMonth March 2026
Dividing Arabidopsis epidermal cells imaged by confocal microscopy after expansion. Microtubules guided cell plate formation revealed in 3D with depth-code.
Image: Magali Grison @lbm-bordeaux.bsky.social @gtexm.bsky.social
#Microscopy #PlantScience #CellBiology

Save the date 🤩🤩🤩!

Our student-led Young Scientist Symposium will take place on the 4th & 5th of June this summer!

More information and registration available soon!

🏆 Image of the Year 2025
226 votes, 12 Images of the Month, and a race decided by just one vote 😮
With 58 votes, @tdhellemmes.bsky.social wins for his cleared brain image acquired using light-sheet microscopy and will proudly carry the colors of the BIC 🎉🔬✨

#ImageOfTheMonth February 2026 ✨
Fluorescent fibers (hundreds of µm) of a Platinium complex visualized in Fiji using orientation-based pseudocolors 🎨. Image acquired during the BIC hands-on microscopy training 🔬
Credits: F. R. Lauro, A. Virepinte (ISM), J. Teillon (BIC)

[WEBINAR] Join the next France Volume-EM WebCafe!

Karin Pernet-Gallay from the GIN (Grenoble) will present her latest project, revealing new insights into astrocyte structure & function. These results would never have been obtained without 3D EM!

🗓️ January, 29th - 13:00
🔗 Join here: bit.ly/49Ux45l

✨ En ce début d’année, l’équipe du pôle photonique s’est dit qu’il était temps de changer des slides et des listes d’équipements 📄❌

👉 Résultat : un mini-film un peu décalé pour présenter nos systèmes de microscopie, d’optique et d’instrumentation 🔬

La photonique, mais en version musicale 🎶

A colorful start to 2026! 🌿 #ImageOfTheMonth
M. Batsale (Plant Virology team, @inrae-bfp.bsky.social ) captured a Nicotiana benthamiana cell infected with turnip mosaic virus — peroxisomes (yellow), viral vesicles (magenta) & chloroplasts (blue).

✨ December 2025 #ImageOfTheMonth ✨
Whole rat hearts cleared with iDISCO reveal sympathetic innervation (orange) and vascularization (green). 💛💚
Work by S. Bertrand & A. Bonilla (INCIA) with S. Martin & I. Brunet (CIRB), imaged by J. Teillon (BIC).

#Microscopy #iDISCO #BICBordeaux

November #ImageOfTheMonth goes to M.Pujol from LPCO lab (UMR 5629). Acquired with Transmission Electron Microscopy, it shows a polystyrene (PS) latex obtained by post-dispersion of a yogurt cup made of PS in water using a surfactant. The resulting particles are highly heterogeneous and large.

‪October #ImageOfTheMonth is from O. Barba-Vila from @iins-bordeaux.bsky.social Slice of the gustatory cortex showing axons from the gustatory thalamus (G), basolateral amygdala (R) and a thick-tufted layer 5 neuron (W), recorded through patch clamp and imaged via biocytin-streptavidin labelling

September #ImageOfTheMonth is from @rkinet.bsky.social from @imn-bordeaux.bsky.social
This is a maximum projection of a confocal image of a microglia cell (blue) and its nucleus (red), internalising multiple nanoparticles (yellow), one day after supranigral injection in C57B6-J mouse

August #ImageOfTheMonth is from L.Congiu from
@imn-bordeaux.bsky.social. This is a 3D reconstruction of a CD68-positive particles (white) within the cell body of microglia cells (Red) in the mouse cortex. The confocal Z-stack was processed with Imaris software.

It’s good to be back at the BIC! @bic-bordeaux.bsky.social 🔬

July #ImageOfTheMonth is from A.Drouet from
@iins-bordeaux.bsky.social. This image represents a neurosphere (150x150 µm) formed from dissociated hippocampal neurons cultured for 14 days under non-adhesive conditions. Yellow shows GFP expressing neurons and nuclei are showed in cyan.

@jeremie-bic.bsky.social

June #ImageOfTheMonth is from L.Boutaleb from @inrae-bfp.bsky.social. They study the impact of heat stress on cell division and DNA replication on the tomato meristem. On this confocal image, EdU staining (magenta) detects replicating DNA and Hoechst labeling (cyan) shows all cell nuclei.

May #ImageOfTheMonth was from C.Mazocco & M.Darricau from @imn-bordeaux.bsky.social. Staining on spinal cord slices reveal TDP43 protein in the nucleus of neurons (Red). Motoneurons and synaptic terminations were stained targetting ChAT (Cyan).

Time to expand your vision! 👀🌱
Our latest work on ExM in plants is out
Back-to-back with the Danzl 's lab (@ISTAustria) led by Magali Grison @lbm-bordeaux.bsky.social with @monica-bic.bsky.social and @gmaucort.bsky.social from the @bic-bordeaux.bsky.social .

academic.oup.com/plcell/artic...

Root expansion microscopy: A robust method for super resolution imaging in Arabidopsis Root expansion microscopy (ROOT-ExM) achieves super-resolution expansion microscopy in plants.

Finally out!, after a few months of delay, our protocol on ExM in plant roots is now available in The Plant Cell
academic.oup.com/plcell/artic...
Beautiful images in a great collaboration of the @bic-bordeaux.bsky.social with @emmanuellebayer.bsky.social and Magali Grison @lbm-bordeaux.bsky.social

April #ImageOfTheMonth is from H. Vaïtinadapoulé (BiiO EA 2521). Here is a guttae, a “drop-like deposits” of extracellular matrix components on the surface of the cornea. This image was acquired using scanning electron microscopy with the help of F.Decoeur from the EM unit of the BIC.

March #ImageOfTheMonth goes to M.Bonhivers from MFP lab (UMR 5234).
Trypanosoma brucei cell was extracted in detergent, expanded 4.2 fold using U-ExM, labelled for the microtubule cytoskeleton (magenta) and for the Hook Complex (yellow), and images usinf scanning confocal microscopy.

Super-resolution microscopy unravels a dynamic tubular network that is stabilized by pre-existing Golgi and lipids to mature into new Golgi pre-cisternae, @bic-bordeaux.bsky.social, @cnrsbiologie.bsky.social, @cnrsaquitaine.bsky.social, #Lipids, #ExpansionMicroscopy, #PlantScience, #PlantCellBiology