Glucose Restriction Extends Chronological Lifespan of Budding Yeast by Avoiding Commonly Used Auxotrophic Marker Nutrient Starvation The survival period of yeast is determined by the type of nutrients they starved of. GR extends lifespan by avoiding auxotrophic starvation. Auxotrophic starvation causes degenerative cellular charac...

In the latest #Yeast research article, Yukinori Ozaki, Taku Ozaki and Qiu-Mei Zhang-Akiyama show that glucose restriction extends chronological #lifespan in budding yeast, while auxotrophic markers can induce abnormal cellular states under starvation.

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onlinelibrary.wiley.com/doi/10.1002/...

I am extremely happy to share that the final paper from my PhD in @litinice.bsky.social 's team at @ircan.bsky.social (Université Cote d'Azur, @cnrscotedazur.bsky.social) is now out in @natcomms.nature.com !!! 😁😁😁

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www.nature.com/articles/s41...

Issue Information No abstract is available for this article.

The new #Yeast issue of January-March 2026 (Volume 43, Number 1-2) is now out, with a review on the role of Rad9 in DNA repair, and three research articles spanning the isolation of yeast species from flowers and honeys, and the effects of furanic compounds.

onlinelibrary.wiley.com/doi/10.1002/...

Influence of Ploidy and Genetic Background on Stress Tolerance of Intraspecific Yeast Hybrids A large set of intraspecific yeast hybrids was constructed using two strategies that yielded series of hybrids with variable ploidy. Phenotyping of the hybrids was carried out in high-stress media to....

In our recent study, we created over 1000 intraspecific yeast hybrids by crossing genetically diverse strains and tested how well they grow under harsh industrial conditions such as high ethanol, salt, and organic acids.

enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/...

CRISPR/Cas9 Genome Engineering in Non‐Conventional Oleaginous Yeasts: Applications, Challenges, and Prospects Given the biotechnological potential of yeast-derived oils for oleochemical production, genes encoding lipid metabolism enzymes are key targets for metabolic engineering. Genetic engineering tools su...

In this #Yeast review article, Wendel Batista da Silveira & team give us an overview of the application of the CRISPR/Cas9 system in oleaginous yeasts. They discuss the main advances in the use of the tool, its technical limitations and future opportunities 🧬

onlinelibrary.wiley.com/doi/10.1002/...

Uptake Mechanisms and Physiological Effects of Furanic Compounds From the Maillard Reaction in Budding Yeast Matos et al. use genetic approaches in Saccharomyces cerevisiae to show toxicity of different furanic compounds can be modulated via regulation of surface nutrient transporters. Distinct furanic comp....

In this #Yeast research article, Laise Cedraz Pinto Matos, Amy Milburn and @yorkyeast.bsky.social investigated the physiological effects of #furanic compounds from the Maillard reaction in yeast & found that they have different uptake, efflux, and toxicity.

onlinelibrary.wiley.com/doi/10.1002/...

Yeasts Isolated From Urban Honeys: Diversity and Potential Application in Mead Production This study aimed to isolate, identify, and evaluate yeasts originating from urban honeys as potential starters for mead production. Honey samples from urban apiaries from Poland were analyzed. A tota...

In the latest #Yeast research article, Joanna Sękul, Anna Maria Kot, Katarzyna Pobiega and team analyze yeasts isolated from Polish urban #honeys and identify honey-derived S. cerevisiae strains that could be used as novel starters for mead production 🇵🇱 🍯 🐝

onlinelibrary.wiley.com/doi/10.1002/...

Candidozyma cisalpinoae sp. nov., a Genomically Distinct, Flower‐Associated Yeast, Resistant to Azoles and Exhibiting Pathogenicity‐Related Traits Candidozyma cisalpinoae sp. nov. represents a distinct species within the Candidozyma clade, supported by multilocus phylogeny, genome-scale metrics, and phenotypic traits. Although isolated from flo...

A new #Yeast has been discovered by Carlos Rosa, Susana Johann & team: Candidozyma cisalpinoae. The new species is resistant to azoles, shows other virulence-associated traits and was isolated from Ipomoea flowers in the Tocantins state, Brazil 🌸 🇧🇷

onlinelibrary.wiley.com/doi/10.1002/...

The Multifaceted Role of Rad9 in the DNA Damage Response of Saccharomyces cerevisiae To maintain the integrity of the genome, cells have evolved a complex signalling system, termed the DNA damage response (DDR), which detects DNA damage and promotes DNA repair. To date, over 600 prot....

In the latest #Yeast review article, A. Kiely, F. O'Halloran, P. Young, N. F. Lowndes, @murielgalway.bsky.social and K. Finn discuss the latest advances in understanding the versatile role of Rad9 in the DNA Damage Response in Saccharomyces cerevisiae 🧬

onlinelibrary.wiley.com/doi/10.1002/...

Yeast | Microbiology Journal | Wiley Online Library Yeast is a microbiology journal for research in the rapidly moving field of yeast biology. We publish the most significant developments in unicellular fungi.

ANNOUNCEMENT: The webpage for the upcoming yeast meetings of 2026 has recently been updated. Have a look at it to find out which exciting #yeast #conferences are ahead!!! 😀

onlinelibrary.wiley.com/page/journal...

Compared to the preprint, we added data on the functional effect of the suppressors (about half are LOF). Thanks again to @leopoldparts.bsky.social @ptck72.bsky.social @markashe.bsky.social @nicolo-tellini.bsky.social and all co-authors without Bluesky accounts!

delighted to have contributed to this editorial led by Sakkie Pretorius on the wave of next generation #yeast scientist

📢 In our new study, we identify the predominant natural route to polyploidy in S. cerevisiae.

Stepwise polyploidization operates through iterative cycles of events termed "Sporulate–Endoreplicate–Mate" (SEM).

Really excellent work led by @cintiagomez.bsky.social 👏

www.biorxiv.org/content/10.6...

Very nice, congratulations

Ancient co-option of LTR retrotransposons as yeast centromeres - Nature Evolutionarily related ‘proto-point’ centromeres providing resolution to the evolutionary origins of point centromeres are identified in yeast, and comparison shows they evolved in an ancestor with re...

Our paper is now out in Nature:

“Ancient co-option of LTR retrotransposons as yeast centromeres”

www.nature.com/articles/s41...

A short thread on how retrotransposons helped give rise to yeast point centromeres.

1/14

With @litinice.bsky.social, we built a haploid resource from 33 wild Taiwanese Saccharomyces cerevisiae strains — including some of the most genetically divergent Asian lineages — to bring natural yeast diversity into a genetically tractable framework. www.biorxiv.org/content/10.6...

There's a lot more juicy stuff inside so I hope you'll give it a read over at @currentbiology.bsky.social ! Thanks to my (Bluesky) coauthors @linder-surprise.bsky.social, @jlsteenwyk.bsky.social, @ana-pontes.bsky.social, @hittingerlab.bsky.social, & @rokaslab.bsky.social!

The deadline for the submission of papers to the special issue on the International Yeast Meetings of 2025 has been extended to 31 March. Papers should be connected to one of the meetings listed below. Hurry up and don't miss this chance!

More information at:
onlinelibrary.wiley.com/page/journal...

Last paper in collaboration with Zhou XU. We explored the natural telomere length diversity in S. cerevisiae and found that ploidy level, and subtelomere structure drive telomere length variation. Higher ploidy levels lead to telomere elongation! genome.cshlp.org/content/earl...

Sponges, ctenophores, and the statistical significance of syntenies Abstract. Shared fusions between ancestral chromosomal linkage groups have previously been used to support phylogenetic groupings, notably sponges with cni

@rcply.bsky.social argues that phylogenetic inferences in sponge–ctenophore–bilaterian relationships based on shared chromosomal rearrangements suffer from insufficient statistical support.

🔗 doi.org/10.1093/molbev/msaf321

#evobio #molbio

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Last work of the lab showing that Repeated losses of self-fertility shaped heterozygosity and polyploidy in yeast evolution | PNAS www.pnas.org/doi/10.1073/...

Happy 40th birthday Yeast: Yeast: Vol 42, No 12 Yeast is a microbiology journal for research in the rapidly moving field of yeast biology. We publish the most significant developments in unicellular fungi.

The new year has just started and we are happy to share the news that the new issue of #Yeast (Volume 42, Number 12, December 2025) is finally out!!! 😀😀😀

This issue includes two research articles and two reviews.

You can browse it at this link:

onlinelibrary.wiley.com/toc/10970061...

Here is our first publication of 2026 which is the first article of a special issue that mark the journal 40 anniversary - happy new year to all the #yeast community

A global synthesis of yeast in microbiomes Yeasts are widespread members of microbial communities across terrestrial, aquatic, and host-associated environments, yet they remain underrepresented in microbiome studies due to low abundance and me...

here is our first contribution of yeast in microbiomes led by Jason Tsai group[ with contributions from Alberto and Nelly: www.biorxiv.org/content/10.6...
more to come

📢 Join us in sunny Lisbon 🇵🇹 2-5 June for the @embo.org workshop ☀️

“The rules of the game: biophysical & molecular principles in cellular evolution”

Apply by March 1st!
Please repost to help spread the word!

meetings.embo.org/event/26-cel...
#EMBORulesOfTheGame @gimmfoundation.bsky.social

Sponges, ctenophores and the statistical significance of syntenies Abstract. Shared fusions between ancestral chromosomal linkage groups have previously been used to support phylogenetic groupings, notably sponges with cni

Some more shenanigans on the Ctenophora Porifera debate from @rcply.bsky.social academic.oup.com/mbe/advance-...

🗞️ New preprint from the lab, led by our postdoc Ana Garoña (not on here) in collab with @andreagiometto.bsky.social: “Experimental evolution of cellular miniaturization reveals a mechanism for cell size evolution”, aka: “honey, we shrank the yeasts!” 🎥
www.biorxiv.org/content/10.6...

Le Dr Isheng Jason TSAI et le Pr. Gianni LITI avec leurs médailles au côté du Pr. Alain FISCHER, président sortant de l'Académie des sciences.

Le Grand Prix scientifique franco-taïwanais 2025 du Conseil National des Sciences de #Taïwan et de @academiesciences.bsky.social a été décerné à Gianni LITI, de l'Institut de recherche sur le cancer et le vieillissement de Nice, et Isheng TSAI, du Biodiversity Research Center de l'Academia Sinica.

So excited to see my PhD work finally being published!!!

It was such a pleasure working with a great team!!!