🎶 Poetry (RNA) in motion: Single-molecule FRET reveals #Yeast tRNAs constantly sample open, compact & intermediate conformations. Pseudouridine synthase Pus4 binding creates new structural states & continues remodeling tRNA post-catalysis
🧬 #YeastResearch 🧪 #SGD 🔬
www.yeastgenome.org/reference/S1...

SGD Help - Gene Registry SGD Help: Gene Registry The SGD Gene Registry is the system used by the S. cerevisiae community and SGD to reserve standard names for newly characterized genes. The Gene Naming Guidelines describe how...

🧬 Characterized an unnamed #yeast #gene?
1. Name with 3 letters + number (ex. XYZ1) to reflect function.
2. Reserve your unique name at SGD while preparing manuscript www.yeastgenome.org/reserved_nam...
3. Include both ORF & gene names in your publication! 📝
Help: sites.google.com/view/yeastge...

Nine white flour yeast bread rolls on a cooling rack. Shades of golden brown. They were scored down the centres longitudinally

The same but photographed at an angle and slight elevation

Nine long rolls.

Next time I do a yeast dough I might try for foot-longs.

🧑‍🍳 🍞 🍽️ 🍜

#food #cooking #baking #bread #yeast #rolls

A cut load of brown bread studded with fruit and nuts. 3 uncut loaves behind.

Today's bake is a buttermilk whole wheat cinnamon bread with craisins and pecans folded in.
#yeast #baking It's honestly amazing.

🌟 #PYFF9 Announcement: Uffe Mortensen 🌟
Thrilled to announce Uffe Mortensen as speaker🎙️
Professor at Technical University of Denmark, he is a leader in #synthetic biology and genome #engineering, developing cutting-edge tools for #yeast and CRISPR technologies.
Looking forward to his insights! 🌿

🎮 Sphingolipid control center: #Yeast ceramide synthase assembles into regulated complexes that modulate ceramide output. Protein oligomerization serves as sophisticated regulatory mechanism during biosynthesis perturbations
🧬 #YeastResearch 🧪 #SGD 🔬

www.yeastgenome.org/reference/S1...

👍 Fine-tuning DNA replication: #Yeast DNA polymerase ε thumb insertion balances processivity & proofreading. Small changes can either boost or reduce performance -> subtle regulation with major consequences for genome stability

🧬 #YeastResearch 🔬 #SGD 🧪
www.yeastgenome.org/reference/S1...

In bottle pressure measuring.

Great device to measure in bottle pressure whilst making sparkling cider by method traditional Inside the champagne bottle, the cider undergoes secondary fermentation stored in our cellar at 13°C, and usually takes 8 weeks to reach full pressure of 5 bar After that the yeast autolyses #cider #yeast

New research in #GENETICS identifies an important role of the Ess1 prolyl isomerase in regulating #telomere transcription and replication in #yeast. buff.ly/MIkyJsr

Randy W. Scheckman presenting a special lecture at our University of Debrecen - he won the 2013 Nobel Prize in Physiology or Medicine for using baker’s #yeast to uncover the genetic machinery regulating vesicle transport!

📈 Resilient reproduction: 1st genome-wide localization of #Yeast Mms4p reveals preference for weak DNA break sites & chromosome axis regions, unlike Msh5 which favors strong sites; the two crossover pathways complement rather than compete
🧬 #YeastResearch 🧪 #SGD 🔬
www.yeastgenome.org/reference/S1...

🧬 Decoding heterosis: Large-scale analysis of #Yeast hybrids shows genetic distance drives stress tolerance gains. Most hybrids display mid-parent #HybridVigor, with strongest benefits in high ethanol and high salt

🔬 #YeastResearch 🧪 #SGD #Genetics
www.yeastgenome.org/reference/S1...

Scientists uncovered the nutrients bees were missing — Colonies surged 15-fold Scientists have developed a breakthrough “superfood” for honeybees by engineering yeast to produce the essential nutrients normally found in pollen. In controlled trials, colonies fed this specially d...

Scientists uncovered the nutrients bees were missing — Colonies surged 15-fold
A lab-made diet supercharged bee colonies and could help save our food supply.
www.sciencedaily.com/releases/202...

#News: Can #yeast save the #rainforests? 🧐🍄 Scientists create "designer enzyme" turning yeast into a #palmoil or #coconut oil alternative! 🛑🌴 🧪✨ #BioTech #BoycottPalmOil #Boycott4Wildlife @palmoildetect.bsky.social https://www.geneonline.com/designer-enzyme-enables-yeast-to-produce-fatty-acids-as-sustainable-alternatives-to-palm-and-coconut-oil/

#News: Can #yeast save the #rainforests? 🧐🍄 Scientists create "designer enzyme" turning yeast into a #palmoil or #coconut oil alternative! 🛑🌴 🧪✨ #BioTech #BoycottPalmOil #Boycott4Wildlife @palmoildetect.bsky.social www.geneonline.com/designer-enz...

🍻🌏🍻 Beyond commercial strains: Native #Yeast species like S. cerevisiae, Brettanomyces & Torulaspora create unique flavors in #CraftBrewing. Review shows how local microorganisms enhance terroir expression while preserving biodiversity
🧬 #YeastResearch 🧪 #SGD
www.yeastgenome.org/reference/S1...

Engineered yeast provides rare but essential pollen sterols for honeybees - Nature Genetic engineering of a yeast strain provides rare but essential pollen sterols for honeybee colonies.

𝗘𝗻𝗴𝗶𝗻𝗲𝗲𝗿𝗲𝗱 𝘆𝗲𝗮𝘀𝘁 𝗽𝗿𝗼𝘃𝗶𝗱𝗲𝘀 𝗿𝗮𝗿𝗲 𝗲𝘀𝘀𝗲𝗻𝘁𝗶𝗮𝗹 𝗽𝗼𝗹𝗹𝗲𝗻 𝘀𝘁𝗲𝗿𝗼𝗹𝘀 𝗳𝗼𝗿 𝗵𝗼𝗻𝗲𝘆𝗯𝗲𝗲𝘀 [via Nature] 🧪🥼🐝🍲🌼

"genetically #engineered a strain of the oleaginous #yeast Yarrowia lipolytica to produce a mixture of essential sterols for #bees"

www.nature.com/articles/s41...

#honey #bee #essential #sterols #yeast

The yeast Kluyveromyces marxianus exhibits unique tolerance of high heat and a subset of chemical stress conditions - Christensen et al. find unique patterns of genetic and regulatory variation in membrane-protein genes and lipid metabolism.

🔗 doi.org/10.1093/gbe/evag060

#genome #evolution #yeast

🔋 Cellular powerhouse assembly: Review details how #Yeast builds & maintains respiratory chain complexes through coordinated nuclear import + mitochondrial protein synthesis, providing key insights into energy machinery biogenesis
⚡️ #YeastResearch 🧪 #SGD 🧬
www.yeastgenome.org/reference/S1...

New research in #GENETICS highlights #autophagy as a key mechanism underlying ASC1-mediated modulation of TDP-43 toxicity in #yeast, suggesting autophagy as a promising therapeutic target in neurodegenerative diseases, such as #ALS. buff.ly/3xi2PAr

Candida Genome Database’s new website is live! #yeast

💞 Cellular matchmaking: #Yeast condensin loop extrusion brings together broken DNA and repair donors during mating-type switching. Study reveals how SMC complexes facilitate homology search by creating specific chromosomal loops

🔬 #YeastResearch 🧬 #SGD 🧪
www.yeastgenome.org/reference/S1...

Genomic and transcriptomic insights into Trichomonascus vanleenenianus, a xylan-degrading yeast isolated from saproxylic insect larvae - BMC Genomics BMC Genomics - Studying microbial biodiversity offers enormous potential for improving the valorisation of plant biomass, particularly in conversion processes. Microorganisms, such as bacteria,...

New paper out! A wood-boring insect larva's gut led us to a xylan-munching yeast! Genome+transcriptome of Trichomonascus vanleenenianus reveals a powerful enzymatic toolkit for plant biomass breakdown, including a GH11 xylanase. #Yeast #Genomics #Xylan 🔗 doi.org/10.1186/s128...

🍺 Perfecting nonalcoholic beer: Study compares maltose-negative #Yeast strains with arrested fermentation approach using high-gravity brewing. Strategic yeast selection + glucose oxidase treatment= ⏫ flavor & ⏬ ethanol

🧬 #YeastResearch 🔬 #SGD 🧪
www.yeastgenome.org/reference/S1...

Latest in #GENETICS: @triggerloop.bsky.social et al. identify new mutations within the #yeast TFIIH-Polymerase II and TFIIE interface that enable changes in the promoter scanning in either upstream or downstream directions.

buff.ly/SEzYBd3

🆕 ADVANCE ONLINE 🆕

RESEARCH PAPER: The LINC complex component Kms1 & CENP-B protein Cbp1 cooperate to enforce faithful homology-directed DNA repair at the nuclear periphery in S. pombe
By Laffitte et al. & Megan King
➡️ https://ow.ly/BRKE50Ywy23

Yale School of Medicine
#yeast #DNArepair

🔥 Heat-resistant breakthrough: Evolved #Yeast strain TT-M6 thrives at high temperatures, producing 74.8 g/L ethanol from lignocellulose at 37°C. A few key mutations enable efficient biofuel production from agricultural waste

🔬 #YeastResearch 🧬 #SGD 🧪 #Biofuels
www.yeastgenome.org/reference/S1...

BEAM Circular Accelerator Powered by gener8tor Announces Second Cohort of Startups Advancing Circular Bioeconomy Innovation renewable-carbon.eu/news/?p=174796 #bioeconomy #biotechnology #catalysts #circulareconomy #fermentation #microbes #packaging #wastemanagement #yeast #RenewableCarbon

Ploidy states (haploid vs diploid) affect the mutation spectrum in the natural populations of two #yeast species—Saccharomyces cerevisiae and Schizosaccharomyces pombe.

Find out more in the March issue of #GENETICS: buff.ly/HbB7vbs

Greyscale image of an outreach event featuring a color-cutout of Kyle David pointing to a dry erase board. Text describes his postdoc of the year award

Greyscale image of a scientific talk featuring a color-cutout of Olivia Riedling explaining her slide. Text describes her pathbreaking discovery award.

Two Rokas Lab members have received high praise from the university this week. Kyle David was named Postdoc of the Year and Olivia Riedling received the Provost Pathbreaking Discovery Award! www.vanderbilt.edu/evolution/two-from-rokas... #Evolution #Yeast

CRISPR/Cas9 Genome Engineering in Non‐Conventional Oleaginous Yeasts: Applications, Challenges, and Prospects Given the biotechnological potential of yeast-derived oils for oleochemical production, genes encoding lipid metabolism enzymes are key targets for metabolic engineering. Genetic engineering tools su...

In this #Yeast review article, Wendel Batista da Silveira & team give us an overview of the application of the CRISPR/Cas9 system in oleaginous yeasts. They discuss the main advances in the use of the tool, its technical limitations and future opportunities 🧬

onlinelibrary.wiley.com/doi/10.1002/...