Advertisement · 728 × 90

Posts by Nils Blüthgen

Post image

Der Vorname des mutmaßlichen Täters, der Anlass für die Aktuelle Stunde im Bundestag „Gewalt gegen Frauen“ war, lautet übrigens: „Christian“.

4 weeks ago 3166 791 91 25
Linocut portrait of biochemist and medical researcher Maud Menten (1879-1960) with the Michalis-Menten equation in blue and a histology image in pinks and purples in the background.

Linocut portrait of biochemist and medical researcher Maud Menten (1879-1960) with the Michalis-Menten equation in blue and a histology image in pinks and purples in the background.

Happy birthday to 🇨🇦Canadian medical researcher & #biochemist Maud Menten (1879-1960). 👩🏼‍🔬🧪🐡 #histsci Not only was she an author of Michaelis-Menten equation for enzyme kinetics, she invented the azo-dye coupling for alkaline phosphatase, 1st example of enzyme histochemistry, still used in imaging of

1 month ago 100 34 2 2
A black-and-white historical photograph of Dr. Maud Leonora Menten (1879–1960), the Canadian physician and biochemist who co-developed the Michaelis–Menten equation for enzyme kinetics. Taken in her laboratory (likely at the University of Pittsburgh in the 1910s–1920s), she stands with a serious, focused expression—lips closed, eyes direct and thoughtful—against a backdrop of wooden shelves filled with glass bottles, jars, scientific equipment, and a wire-mesh enclosure. She wears a dark dress with a lace collar, a string of beads, and her hair styled in a neat bun. Superimposed on the image is the Michaelis–Menten equation in white text:v=Vmax⁡[S]Km+[S]v = \frac{V_{\max} [S]}{K_m + [S]}v = \frac{V_{\max} [S]}{K_m + [S]}
This iconic portrait captures Menten during her groundbreaking research in biochemistry and histochemistry, where she helped establish the foundational mathematical model of enzyme-substrate reactions still used today, while overcoming significant gender barriers as one of the first women in Canada to earn both an M.D. and a Ph.D.

A black-and-white historical photograph of Dr. Maud Leonora Menten (1879–1960), the Canadian physician and biochemist who co-developed the Michaelis–Menten equation for enzyme kinetics. Taken in her laboratory (likely at the University of Pittsburgh in the 1910s–1920s), she stands with a serious, focused expression—lips closed, eyes direct and thoughtful—against a backdrop of wooden shelves filled with glass bottles, jars, scientific equipment, and a wire-mesh enclosure. She wears a dark dress with a lace collar, a string of beads, and her hair styled in a neat bun. Superimposed on the image is the Michaelis–Menten equation in white text:v=Vmax⁡[S]Km+[S]v = \frac{V_{\max} [S]}{K_m + [S]}v = \frac{V_{\max} [S]}{K_m + [S]} This iconic portrait captures Menten during her groundbreaking research in biochemistry and histochemistry, where she helped establish the foundational mathematical model of enzyme-substrate reactions still used today, while overcoming significant gender barriers as one of the first women in Canada to earn both an M.D. and a Ph.D.

Chemist/physician Dr. Maud Menten co-authored the seminal paper 𝘋𝘪𝘦 𝘒𝘪𝘯𝘦𝘵𝘪𝘬 𝘥𝘦𝘳 𝘐𝘯𝘷𝘦𝘳𝘵𝘪𝘯𝘸𝘪𝘳𝘬𝘶𝘯𝘨, 1931. This intro'd the Michaelis–Menten equation (image). It remains a cornerstone of #biochemistry, used in drug design, metabolic studies & enzyme engineering. She was born #OTD in 1879.

#WomenInSTEM

1 month ago 191 73 1 4
Projection of an intro slide for the conference

Projection of an intro slide for the conference

Thrilled to be at the 2nd Bonn conference on mathematical life sciences. Great to see a huge lecture hall full of people at the kickoff of the conference, all working at the interface of maths and biology.

1 month ago 6 0 0 0

Was ist drin? Klopapier, Nudeln, Internet?

1 month ago 2 0 1 0

Toll, dass die Berliner Behörden jetzt verstanden haben, wie Cell Broadcast grundsätzlich funktioniert, jetzt vielleicht noch ne Schulung zum sinnvollen Einsatz, danke.

3 months ago 570 61 4 7
Post image Post image Post image

Zell- & Molekularbiologin Kerstin Kaufmann wird Einstein-Prof & bleibt an der @humboldtuni.bsky.social! Durch Koops mit BIMSB, @mpi-mp-potsdam.bsky.social & @igzleibniz.bsky.social vernetzt sie Molekularbiologie, quantitative Modellierung & Bioengineering.
www.einsteinfoundation.de/presse/2026/...

3 months ago 5 1 0 1
Advertisement
Post image

Fig. 6: Mathematical model

4 months ago 106 12 2 3
Preview
Offener Brief an die Bundestagsfraktionen von CDU/CSU, SPD, Bündnis 90/Die Grünen und Die Linke zur Rückkehr der grundsätzlichen Öffentlichkeit der Sitzungen des Forschungsausschusses An die Vorsitzenden der Bundestagsfraktionen von CDU/CSU, SPD, Bündnis 90/Die Grünen und Die Linke Berlin, 19.11.2025 Öffentlichkeit im Bundestagsausschuss für Forschung, Technologie, Raumfahrt und T...

Der #Forschungsausschuss des Bundestags tagt nicht mehr öffentlich — das war’s dann mit Tranzparenz wissenschaftspolitischen Handelns auf Bundesebene! Erschwert die Arbeit von Journalist_innen ebenso wie unsere für #IchBinHanna uvm. massiv. @wpk.bsky.social fordert in 1 offenen Brief, das zu ändern:

5 months ago 120 50 1 5
Preview
Charité-Chef Heyo Kroemer über Kürzungsfolgen: „Bei keinem Uniklinikum in Deutschland wird derart gespart“ 56 Millionen Euro weniger Zuschüsse bekomme das Berliner Uniklinikum 2026, sagt Charité-Chef Kroemer. Das wird sich auf Berlins medizinische Versorgung auswirken – und könnte die Spitzenstellung in de...

Die Charité-Chefs haben am Montag im Berliner Wissenschaftsausschuss die Folgen der Kürzungen für die Uniklinik skizziert. "Drittmittel werden sinken, Ambulanzen müssen schließen“, fasste Dekan Joachim Spranger es zusammen. (T+) www.tagesspiegel.de/wissen/chari...

5 months ago 26 11 0 1
Bill from DM

Bill from DM

Welcome our new colleagues: Prof. Flasche aus Ede and Prof. Geschirrschwämme! Looking forward to working with you!

5 months ago 5 0 0 0

Yeah!

5 months ago 0 0 0 0

Aim high 🚜 !

5 months ago 0 0 0 0

Finally! 🚜

5 months ago 0 0 0 0
Email: Dear Nils Blüthgen,
Cureus Journals, a part of Springer Nature, will be launching its fourth open access journal—Cureus Journal of Agriculture and Food Science (CJAF)— in December 2025. 
 
I would like to take this opportunity to invite you to apply for a position on our esteemed Editorial Board as an Associate Editor (AE) for CJAF.

Email: Dear Nils Blüthgen, Cureus Journals, a part of Springer Nature, will be launching its fourth open access journal—Cureus Journal of Agriculture and Food Science (CJAF)— in December 2025. I would like to take this opportunity to invite you to apply for a position on our esteemed Editorial Board as an Associate Editor (AE) for CJAF.

I always wanted to join the editorial board for an agricultural journal. Clearly my expertise. Will be a great journal 🤡
#scientificspam

5 months ago 7 0 5 0
Preview
Senat will 12,5 Millionen Euro investieren: NFL kommt 2025 für ein Spiel nach Berlin Die nordamerikanische Football-Liga NFL wird 2025 ein Spiel in Berlin austragen. Bis 2029 könnten zwei weitere Folgen. Die Kosten dafür sind hoch. Das Land muss trotz Haushaltskrise Millionen investie...

Berlin’s senate invests >12 mio EUR for 3 NFL games in Berlin, at a time where they cut millions at the universities that are already underfunded, with collapsing buildings. They definitely seems to have priorities that are not mine.
www.tagesspiegel.de/berlin/senat...

5 months ago 15 5 2 0
Advertisement
Email: Hi Professor Nils Blüthgen,

My name is xxx yyy, I am a PhD student passionate about economics and entrepreneurship. I came across your work “Quantitative modeling of signaling in aggressive B cell lymphoma unveils conserved core network”, a piece that truly stands out for its precision and contribution to society in the field of finance.

Email: Hi Professor Nils Blüthgen, My name is xxx yyy, I am a PhD student passionate about economics and entrepreneurship. I came across your work “Quantitative modeling of signaling in aggressive B cell lymphoma unveils conserved core network”, a piece that truly stands out for its precision and contribution to society in the field of finance.

“Stands out … for its contribution to the society in the field to finance”???? Maybe the most bizarre spam email I ever received…

5 months ago 3 1 0 0
Preview
Reporter CRISPR screens decipher cis-regulatory and trans-regulatory principles at the Xist locus - Nature Structural & Molecular Biology Here Schwämmle et al. develop CRISPR reporter screens to map transcription-factor-regulatory element interactions at the Xist locus, revealing a two-step mechanism integrating developmental and X-dosage signals to initiate X-chromosome inactivation.

⚠️ Paper alert: Using a novel CRISPR screening approach, we mapped the entire regulatory network controlling Xist—key for X-chromosome inactivation.
👉 We discover how sex and development signals are decoded at a single gene locus.
www.nature.com/articles/s41...
👇 Bluetorial

6 months ago 111 50 3 2
Preview
a cartoon of donald trump with the words be prepared above him ALT: a cartoon of donald trump with the words be prepared above him

When I was at NIH and shutdowns loomed, it was discovered that the administration was planning to shut down PubMed. The head of NCBI called the powers that be and pointed out that this would threaten patient safety

Who knows what will happen now

Just in case, remember Euruope-PMC
(europepmc.org )

6 months ago 168 90 8 10
Preview
Wissenschaftliche Resilienz: Auf dem Weg aus der PubMed-Abhängigkeit – Deutsches Ärzteblatt

The Ärzteblatt asked me about the instability of Pubmed (Why my? Don't know...). Not sure if I agree with the colleagues that we should build up national resources, I rather think we should strengthen existing European ones (e.g. EuropePMC, ENA, EGA...)... www.aerzteblatt.de/archiv/wisse...

6 months ago 8 0 0 0
Nicky McGranahan

Nicky McGranahan

Nicky McGranahan kicking off the last day showing the evolutionary history of metastasis. Amazing data and analysis.

6 months ago 2 1 0 0
Students discussing at poster

Students discussing at poster

Impression of the poster session at bimsb, showing the staircase

Impression of the poster session at bimsb, showing the staircase

Students discussing at poster

Students discussing at poster

Very dynamic poster sessions at the late summer school on tumor heterogeneity and treatment followed by a rooftop party. Thank you @mdc-bimsb.bsky.social for hosting us!

6 months ago 4 2 1 0
Tancredi Massimo

Tancredi Massimo

Adila Apsara

Adila Apsara

Siddharth Annaldasula

Siddharth Annaldasula

Great talks from PhD students Tancredi Massimo Pentimalli, Adila Apsara: and Siddharth Annaldasula!

6 months ago 3 1 1 0
Efrat Shema

Efrat Shema

Efrat Shema kicking off today’s program with a lecture on epigenetics and single cell methods.

6 months ago 4 1 0 0
Finja Becker introducing Sven Nelander

Finja Becker introducing Sven Nelander

Final session for today: Sven Nelander discusses how patient specific models combined with advanced molecular biology and large scale computation allow for a better understanding of CNS cancers.

6 months ago 2 1 1 0
Advertisement
Ido Amit

Ido Amit

Anton Henssen

Anton Henssen

We continue with Ido Amit who shows how single cell approaches allow to improve immune therapy and Anton Henssen introducing us to the world of extrachromosomal DNA and how this relates to tumor heterogeneity. Fascinating!

6 months ago 3 2 1 1
Ulrich Keilholz

Ulrich Keilholz

Heiko Enderling

Heiko Enderling

First session: Uli Keilholz of the comprehensive cancer center on how complex data and models are now used in the clinics, and Heiko Enderling on modeling approaches. Both show excellent examples on how computation already now is impotent for clinical decisions, and how it will be in future.

6 months ago 4 1 1 0
Foto of the kickoff and welcome.

Foto of the kickoff and welcome.

Kicking off today’s Late Summer School on tumor heterogeneity and treatment resistance with an amazing program. Great to see a huge turnout!

6 months ago 2 1 0 0
Preview
Rapid UPF1 depletion illuminates the temporal dynamics of the NMD-regulated human transcriptome UPF1 depletion inhibits nonsense-mediated mRNA decay (NMD) and stabilizes direct target transcripts within hours. Boehm et al. use conditional protein degradation and advanced transcriptomics to map t...

Very harmonious and inspiring collaboration with Niels Gehring, @volkerboehm.bsky.social and team at Uni Köln, and colleagues at @mdc-berlin.bsky.social . Rapid UPF1 depletion illuminates the temporal dynamics of the NMD-regulated human transcriptome: Molecular Cell www.cell.com/molecular-ce...

7 months ago 30 11 1 1
Poster of CompCancer Seminar Series

Poster of CompCancer Seminar Series

Join us for our first CompCancer seminar this fall on Thursday, 4pm with Chris Sander (Harvard): „Catch Cancer Early with the Help of AI Tools“. Maud Menten Room, House 18, Campus Nord HU

7 months ago 4 1 0 0