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Posts by Joy Karmakar โ™พ๏ธ

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Lilly to buy narcolepsy drug developer for $6.3 billion The pharma giant has agreed to acquire Centessa Pharmaceuticals

In one of the largest biopharma acquisitions so far this year, Eli Lilly and Company is slated to buy Centessa Pharmaceuticals, maker of a narcolepsy drug candidate that analysts believe could have blockbuster potential.

#chemsky ๐Ÿงช

2 weeks ago 8 5 0 0
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How to build an AI scientist: first peer-reviewed paper spills the secrets AI Scientist, an autonomous research tool, first released in 2024, has now undergone peer review, highlighting its strengths and limitations.

How to build an AI scientist: first peer-reviewed paper spills the secrets www.nature.com/articles/d41...

3 weeks ago 4 2 0 0
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When AI Writes, Reviews, and Reads
ACS Energy Letters Editorial pubs.acs.org/doi/10.1021/...
If in the future, manuscripts are composed with AI assistance, reviewed by AI tools, and ultimately read and summarized by AI platforms, what will be the role of humans in scientific publication?

1 month ago 4 2 0 0

The only reason why bad people get away is that they know good people will never do bad things to bad people!

1 month ago 1 0 0 0
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The political effects of Xโ€™s feed algorithm - Nature Among users initially on a chronological feed, 7 weeks of exposure to Xโ€™s algorithmic feed in 2023 shifted political attitudes and account-following behaviour in a more conservative direction compared...

X's algorithm isn't neutral (as we all suspected) - it's pushing users toward the conservative side.

The study also found that the algorithm promotes conservative content and DEMOTES posts by traditional media.

Read: nature.com/articles/s41...
#SocialMedia #Algorithms #Politics

1 month ago 1 1 0 0
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Jennifer Doudnaโ€™s $1 Billion Plan To Bring Gene Editing To The Masses Crisprโ€™s ability to cut genetic code like scissors has just started to turn into medicines. Now, gene editing pioneer Jennifer Doudna wants to build an entire ecosystem to bring these treatments mains...

โ€œThe best that I can do in terms of making the next breakthrough or discovery is not to do it by myself, but to enable other scientists to do itโ€
โ€” Jennifer Doudna

www.forbes.com/sites/amyfel...

2 months ago 101 19 4 0
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Standing in the Temecula Valley museum, paired with Ralph Loveโ€™s painting of the old town, it reminds me how history layers over the land we walk today.
Read it ๐Ÿ‘‡

2 months ago 0 0 0 0
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West Coast, best glow. ๐ŸŒ…โœจ

๐Ÿ“La Jollla

2 months ago 0 0 0 0
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DyeMind | AI-Powered Fluorophore Intelligence Discover, compare, and analyze fluorescent molecules with advanced AI assistance.

DyeMind is Live โ€“ your all-in-one AI-platform for Fluorophore Intelligence!

The platform offers a variety of features๐Ÿ‘‡
๐Ÿ”น Curated library of compounds
๐Ÿ”น Real-time spectral comparisons
๐Ÿ”น Auto-QY calculator
๐Ÿ”น Generative design for custom probes

Join โ†’ www.dyemind.com

#FluorescentFriday #RealTimeChem

2 months ago 3 1 0 0
A scientific promotional image showing a platinum porphyrinโ€“based chemical structure on the left, with long alkyl chains substituents. At the top center, a photograph shows a dark red viscous liquid being poured from a spoon into a dish. At the top right, two fluorescence images compare a bright red emission under nitrogen (Nโ‚‚) with a dimmer signal in air, labeled โ€œQuenching.โ€ At the bottom right, a Stern-Volmer plot displays a linear signal increase in a graph with oxygen concentration from 0% to 100%. At the lower center, a yellow box lists features of the optical oxygen sensing: sensitivity, linearity, photostability, and ratiometry.

A scientific promotional image showing a platinum porphyrinโ€“based chemical structure on the left, with long alkyl chains substituents. At the top center, a photograph shows a dark red viscous liquid being poured from a spoon into a dish. At the top right, two fluorescence images compare a bright red emission under nitrogen (Nโ‚‚) with a dimmer signal in air, labeled โ€œQuenching.โ€ At the bottom right, a Stern-Volmer plot displays a linear signal increase in a graph with oxygen concentration from 0% to 100%. At the lower center, a yellow box lists features of the optical oxygen sensing: sensitivity, linearity, photostability, and ratiometry.

โœจNEW in Chemical Science!

"Luminescent core-isolated solvent-free liquids as a soft material platform for optical gas sensing" by Shinsuke Ishihara and Takashi Nakanishi et al. Takashi Nakanishi

Read it here: doi.org/10.1039/D5SC...

2 months ago 7 1 0 2
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Drug dose monitoring with a DNA-based microneedle sensor Aptamer-coated microneedle patch can detect amounts of the antibiotic vancomycin in real time for at least 12 hours

Drug dose monitoring with a DNA-based microneedle sensor

Aptamer-coated microneedle patch can detect amounts of the antibiotic vancomycin in real time for at least 12 hours

cen.acs.org/analytical-c...

#chemsky ๐Ÿงช

2 months ago 15 2 0 0
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As AI enters the operating room, reports arise of botched surgeries and misidentified body parts Medical device makers have been rushing to add AI to their products. While proponents say the new technology will revolutionize medicine, regulators are receiving a rising number of claims of patient ...

AI in the OR goes wrong: FDA gets 100+ unconfirmed reports of malfunctions & adverse events after adding AI to a sinus surgery device.

Botched surgeries & misidentified body parts raise alarms.

#AIinMedicine #PatientSafety #AI

www.reuters.com/investigatio...

2 months ago 1 1 0 0
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Hello, World! ๐Ÿงช www.dyemind.com

#RealTimeChem

2 months ago 4 1 0 1

Do you know any researchers that have made significant contributions to digital #chemistry, #AI, #machinelearning and #automation and has published in Chemical Science within the last five years?

Find out how to nominate the for the 2026 Chemical Science Lectureship here: rsc.li/chemsci-lect...

2 months ago 5 8 0 0
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Hallmarks of cancerโ€”Then and now, and beyond Hanahan revisits the evolving framework of cancer hallmarks, synthesizing 25 years of conceptual refinement into a multidimensional view of tumor biology. This review highlights how aberrant capabilit...

Follow up to Doug Hanahanโ€™s visionary article about the stages of cancer development from back in the 1990s

www.cell.com/cell/fulltex...

2 months ago 29 13 1 0
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How to put drug leads forgotten in the freezer back to work Open science advocates create a guide to sharing medicinal molecule collections

Chemists at University College London propose that academics store and share their medicinal chemistry collections in 96-well plates. cen.acs.org/pharmaceutic... #chemsky ๐Ÿงช

2 months ago 9 5 1 0
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Performance of AI agents based on reasoning language models on ALD process optimization tasks In this work we explore the performance and behavior of reasoning large language models to autonomously optimize atomic layer deposition (ALD) processes. In the ALD process optimization task, an agent...

Can AI agents based on reasoning large language models optimize materials synthesis processes, such as atomic layer deposition? Mostly, except when they are misled by their own choices. Preprint is out: arxiv.org/abs/2601.09980 ๐Ÿงช

2 months ago 8 3 0 0

The most significant challenge I encountered while developing an AI agent for chemistry is the paywall of journals!

There should be a universal rule that mandates all journals to make all their data publicly accessible after certain period.

Until then, we canโ€™t democratize science, even with AI.

2 months ago 1 0 0 0

Thatโ€™s why I built @dyemind.com

2 months ago 1 0 0 0
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New preprint! The remarkable stability of proline-derived cofactors opens efficient DNA labeling possibility using methyltransferases even at harsh conditions.

www.biorxiv.org/content/10.6...

Congratulations to Ruta and Jonas .

#Biochemistry #DNA #Fluorescence

2 months ago 5 1 0 0

If you are working with #fluorescent probe, give it a try!

2 months ago 1 0 0 0
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๐Ÿšจ Swedish researchers at the Karolinska Institutet conducted a comprehensive study on over 8,000 children, concluding that extensive social media use is associated with a gradual decline in their ability to concentrate.

#ADHD #SocialMediaBan

publications.aap.org/pediatricsop...

4 months ago 1 0 1 0
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In 2018, I had the privilege of hearing Prof. Omar Yaghiโ€™s lecture at the Technion, when he received the Wolf Prize in Chemistry.

Itโ€™s wonderful to see him honored with the 2025 #NobelPrize in Chemistry, together with Prof. Kitagawa and Prof. Robson, for their work on reticular chemistry and MOFs.

6 months ago 2 0 0 0
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๐Ÿ“ขNew perspective on light responsive imine-based systems out now in @chemicalscience.rsc.org with @jiarongwu.bsky.social ๐Ÿ’ก๐Ÿšจ๐Ÿ”ฆ This is part of the 2025 Leading Investigators Collection, Thank you to the reviewers for input ๐Ÿ™ #hot #photoswitch #imine imineswitch.com
doi.org/10.1039/D5SC...

7 months ago 15 5 2 0
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Capital Hill is beautiful!

7 months ago 4 0 0 0
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A new generative AI approach to predicting chemical reactions The new FlowER generative AI system may improve the prediction of chemical reactions. The approach, developed at MIT, could provide realistic predictions for a wide variety of reactions, while maintai...

System developed at MIT could provide realistic predictions for a wide variety of reactions, while maintaining real-world physical constraints.
#ArtificialIntelligence #Chemistry
news.mit.edu/2025/generat...

7 months ago 4 0 0 0
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During Golden Hour!
#SanDiego

7 months ago 5 0 0 0
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We're living in such unique times; who would've thought we'd see the day when protests erupt over the banning of popular social media apps? Digital rights and tech politics are now everyone's business. Remarkable, isn't it?
#GenZProtest #Nepal

7 months ago 1 0 0 0
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Innovative Supramolecular Crystals Unlock High-Capacity Hydrogen Storage In the relentless pursuit of sustainable energy solutions, hydrogen has emerged as a linchpin in the transition away from fossil fuels. However, one of the most persistent challenges that has hampered

"Closer to a future where hydrogen is not merely an alternative energy source but a dominant one."
#HOF s
bioengineer.org/innovative-s...

7 months ago 2 1 1 0