Model of N/C as a universal clock of ZGA
This finding provides broad comparative support for the longstanding hypothesis that the nuclear-to-cytoplasmic (N/C) ratio acts as a timer of genome activation. Moreover, this scaling accurately predicts ZGA timing across diverse animals from genome size and egg volume of a species alone. 8/15
Strong negative correlation between log DNA size / egg volume & ZGA onset in cell cycles
Then, what determines ZGA onset?? We correlated multiple genomic, developmental and ecological features with ZGA timing and, cutting to the chase, we found that the log ratio of genome size vs. egg volume very strongly scaled negatively with ZGA onset in cell cycles! 7/15
Thrilled to present our comparative study on the evolution of zygotic genome activation (ZGA)!! 🥚🧬
Amazing PhD work of @campobes.bsky.social together with @fedemantica.bsky.social and many collaborators! @melisupf.bsky.social @crg.eu. Thread below 1/15
www.biorxiv.org/content/10.6...
New paper from the lab out in Cell Death & Disease
@cddpress.bsky.social @cbm-csic-uam.bsky.social
"Transcription-dependent and -independent functions of Drosophila p53 isoforms in the induction of apoptosis and senescence-associated tumorigenesis.” #p53 #Drosophila Thread 1/9👇👇👇
📢 New on the SEBD blog!
#GFE2026 reflections & experiences shared by our #SEBD travel awardees 🌍✨
Don’t miss their unique perspectives and key takeaways 👇👇🏻
sebioldev.blogspot.com/2026/04/germ...
@gfeev.bsky.social
#devbio 🧪
The #SEBD offers its junior members (PhD students and postdocs) travel grants to attend #SEBD meetings. In the last #GfESEBDDSDB joint meeting the awardees were Miguel Angel Garitagoitia, CNIC , Jorge Mañes @cbm-csic-uam.bsky.social and Daniel Barcenilla @cabd-upo-csic.bsky.social. Join the #SEBD!
The 2026 call for the José Luis Gomez-Skarmeta award of excellence in #DevBio is now open! If you’d like to join the previous awardees @dariloops.bsky.social 2024 and @mirimiam.bsky.social and @radaiglesiaslab.bsky.social 2022, please don’t hesitate to apply to #JLGS2026
Thanks to Girish Kale (@girishkalephd.bsky.social) for reporting on our joint developmental biology meeting in Potsdam #GfE2026 #GfESEBDDSDB2026. enjoy the read: thenode.biologists.com/meeting-repo...
looking forward to seeing you and @the-node.bsky.social at #GfE2028
Grateful to be part of this great team. Thanks to @eliasbarrigalab.bsky.social for all the coordination effort! Looking forward to the exciting science to come.
Special congrats to @hlemmik.bsky.social, @thezgs.bsky.social, @nathaliejuya.bsky.social, @neurofishh.bsky.social, @jrmarmor.bsky.social, @eliasbarrigalab.bsky.social, @heisenbergcplab.bsky.social, @ehannezo.bsky.social, @mvargam.eurosky.social, & @fabianlab.bsky.social among others! 🎉 #YouRock
The 2026 Visual System Development GRC and GRS are fast approaching. Jeremy Kay, Kristen Kwan, Robert Johnston, and I have built an exciting program that we hope you will enjoy. Looking forward to seeing everyone at the meeting this summer in beautiful Maine. Register and RT!
Enhorabuena al equipo que está por detrás de #METALoci ahora publicado en en Nature Structural & Molecular Biology. En particular en grupo de @dariloops.bsky.social del #CABD que comparte autoría senior con Marc A. Marti-Renom @crg.eu @cnag-eu.bsky.social y Blanche Capel @durham.ac.uk
(1/5)
Youthful antics predict lifespan? Using machine learning & continuous recordings of #killifish behavior from adolescence until death, @brunetlab.bsky.social & @deisseroth.bsky.social find early-life behavior predicted future lifespan! Now published @science.org: www.science.org/doi/10.1126/... 🧪 1/2
Amazing work!
What a way to start the second day of #GfESEBDDSDB2026 ! A Keynote lecture by Isabel Fariñas @farinaslab.bsky.social introduced by our president Eloisa Herrera @eloisaherrera.bsky.social
We continue the morning with a session on “Forces define form - mechanobiology” with 2 #SEBD representatives, Jerome Solom from Biofisika Institute (CSIC, EHU) and Cielo Centola from @cabd-upo-csic.bsky.social
Cielo Lucía Centola (from @jrmarmor.bsky.social lab) investigates how "Rhythmic contraction waves trigger the Yap-dependent mechanoregulatory loop fueling gastrulation movements in medaka"
Cielo Centola and @jrmarmor.bsky.social from #CABD are participating in the Joint Meeting #gfe2026 in Potsdam!!!
Un recuerdo hoy (y todos los días) para todas las mujeres investigadoras, en el #DiaInternacionalDeLaMujer #8M seguimos implicados todos/as para conseguir la tan deseada igualdad entre hombres y mujeres lo antes posible.
Ya vamos tarde. 💜
@cnb-csic.bsky.social @sebbm.bsky.social @csic.es @uam.es
#CABDseminars
"Temperature and timing in embryonic development " by Michael Dorrity, @embl.org Heidelberg, Germany
🗓️ March 6th
⏰ 12 pm
📍Rosalind Franklin Auditorium, CABD
Hosted by @crisprscan.bsky.social & @jrmarmor.bsky.social
Don't miss Sofía Manzo explaining her PhD project at ProgRET. About short living killifish and retinal disease.
A white statue of Charles Darwin sitting crossed legged on a chair. On the image, there’s text saying ‘Happy 217th birthday Charles Darwin!’. A birthday hat with polka dots has been photoshopped on top of the statue’s head.
Guess who’s turning 217 today? It’s Charles Darwin! 🥳
Born in 1809, he transformed the way we understand the natural world. He developed the theory of evolution by natural selection in his 1859 best-seller, ‘On the Origins of Species’.
Send him your birthday wishes in the comments! 👇
I think that, like with art, papers offer an opportunity for you to tell the story your own way. Could another person research the same question? Yes. However, each person has the opportunity to do it and communicate it in their own way, and we must protect that 🧪
Lamentamos profundamente el fallecimiento de nuestro socio Máximo Ibo Galindo, investigador de encefalopatías del desarrollo, como el síndrome de Dravet y pionero en la utilización de #Drosophila en la investigación de enfermedades humanas en España. DEP
The moment to celebrate a paper is when it’s shared with the world, not when it passes the arbitrary hurdle of “acceptance”
And finally, we have It out! Do not miss It, If you are into early eye development, GRNs, and eye malformations. Thanks to Javier Macho and the rest of the authors for a terrific job.
Single-cell multiomics identifies key nodes and cis-regulatory elements of the networks specifying the eye domains in zebrafish www.biorxiv.org/content/10.64898/2026.01...
Thanks lot! It took some time, but we have It out!
Ludovica Ciampi, investigadora posdoctoral Juan de la Cierva en el laboratorio de @jrmarmor.bsky.social nos cuenta su trabajo entendiendo a nivel de celular única como las células de la retina se comportan en situaciones fisiológicas y de en enfermedad. #TodasHacemosCiencia
@csic.es
This summer I had the chance get to know a quite comprehensive representation of the medaka community in an exciting meeting in Heidelberg. I am very grateful for the experience! Now everybody can have a glimpse on what was discussed.
anatomypubs.onlinelibrary.wiley.com/doi/10.1002/...
