🥤#KidneyStone prevention — diet that protects your #kidneys 👇

🔗 doi.org/10.1136/post...

#Nephrology #Urology

🔍Proteinuria in monoclonal gammopathy? Don’t miss the diagnostic clues!

🚰uAPR < 40%? Think tubular
🧪uAPR > 40%? Glomerular path ahead

From cast nephropathy to MGRS, biopsy is 🔑

📉LC ≤10%= cast nephropathy
📊LC >10%= #LCPT

🧬 #MGRS = Biopsy it

🔗 doi.org/10.1016/j.lp...

#NephSky #MGRS #MM #Medsky

📉 Why are infections so common—and deadly—in people with chronic kidney disease?

🧠 SIDKD (Secondary Immune Deficiency of Kidney Disease) affects gut health, immune cells, metabolism & more.

This visual breaks it down beautifully 👇
🔗 doi.org/10.1097/IMNA... 🆕

🧬 Nephrologists, time to zoom in!

🚨NEW Weapons vs #MDR bugs!

💉Explore 3️⃣ hot β-lactam/β-lactamase inhibitor combos:

🦠 Cefepime/enmetazobactam
🦠 Aztreonam/avibactam
🦠 Sulbactam/durlobactam

⚖️💧Renal dose adjustments? Covered👇

🔗 doi.org/10.3390/path... 🆕

#Nephrology #MedTwitter #ICU #ID #Antibiotics #IM

Reducing CKD burden in Europe: first make the elephant apparent!

doi.org/10.1093/ckj/...

Chronic Kidney Disease in Older Adults: Trends in Prevalence and Healthcare Service Quality from 2012 to 2018 AbstractBackground. Data on the healthcare service quality for patients with chronic kidney disease (CKD) are vital for guiding practitioners, patients, an

Chronic Kidney Disease in Older Adults: Trends in Prevalence and Healthcare Service Quality from 2012 to 2018

doi.org/10.1093/ckj/...

💊💓HFrEF management is evolving!
Why wait months to optimize therapy?

👇Compare ESC 2021 vs McMurray/Packer 2021 strategies

💥 SGLT2i | GLP-1RA | Finerenone

Game-changers in 🫀, 🫘 & 🧠

🔗 doi.org/10.3390/jcm1...

#Nephrology #Cardiology #MedEd #SGLT2i #HeartFailure #CKD #IM #MedSky

🥩🫘#HRS-AKI is more pre-renal than pre-renal AKI!🤯

Check out this mind-bending FENa table in cirrhosis-related AKI from a must-read #ICU review

🔑note: FENa is helpful—but don’t overtrust it alone!

🔗 doi.org/10.1177/0885... 🆕

#Nephrology #MedEd #AKI #Hepatology #Cirrhosis #NephSky #Hepatorenal

🚨#SGLT2 inhibitors in cirrhosis? Where #Nephrology meets #Hepatology

🧪11/11:↓ ascites (💧less taps)
📉7/9: slowed progression (fewer decompensations)
⚠️AKI/hypotension in refractory cases—balance matters!

Dual win:Natriuresis + anti-inflammatory

🔗 doi.org/10.3390/ijms...

🎛️Hemoadsorption in septic shock? Not so fast ❌

🚫 Immune meddling, 🎯 non‑selective action, 📉no survival edge &⚠️ potential harm

🔥 Massimo et al. editorial a must‑read for ICU & nephro teams

🔗 doi.org/10.1007/s001... 🆕

#Nephrology #ICU #Sepsis #AKI #CriticalCare #NephSky

🚨Peripheral Artery Disease🦵 is up to 6x more common in CKD 🫘

❤️‍🔥Vascular calcification, inflammation & CKD-MBD🦴 fuel the fire 🔥

📉Don’t miss early signs—ankle-brachial index can help!

🔗https://doi.org/10.1093/ckj/sfaf089 @ckj-era.bsky.social review

#MedSky #MedEd #CKD #PAD #Nephrology #NephSky

🦸‍♂️🦸‍♀️ Meet the Dynamic Duo in HFpEF/HFrEF!

SGLT2 inhibitors🟰Robin
Finerenone🟰Batman

Together they battle heart failure💔 with preserved/mid-range EF!

🔗 doi.org/10.36660/abc...

#NephSky #CardioRenal #HFpEF #SGLT2i #Finerenone #HeartFailure #MedSky #InternalMedicine

🧬🔬Renal biopsy says amyloidosis… what next?

This brilliant IHC-based algorithm 🔁 guides you through AL, AA, & rare amyloid types—don’t miss that dual diagnosis!

🔗 doi.org/10.1159/0005... 🆕

#RenalPath #Amyloidosis #Nephrology #MedSky #BlueSky

🫀Heart Failure in CKD🫘 isn’t just about fluid overload — and its Rampant in CKD 🔥-it’s a perfect storm of:

🧬Neurohormones
🦠Inflammation
🧪Uremic toxins
🧱Fibrosis
💣Metabolic chaos

🔗 doi.org/10.1161/CIRC...

#Nephrology #CRS #HF #HeartFailure #CKD #FOAMed #MedEd #IM #NephSky #MedSky

🤔Ever seen IgG3 act this wild in the kidney?🫘

🔬PGNMID = mysterious monoclonal Ig with renal-limited fury

🧩Pathophys still unclear but beautifully illustrated here👇

📖Bridoux et al @ndt-era.bsky.social

🔗 doi.org/10.1093/ndt/...

#Nephrology #MGRS #PGNMID #MedTwitter #RenalPath #NephTwitter

🚀Adrenal Incidentalomas Demystified

🥴Stumbled upon an adrenal mass ? Here’s your roadmap🚏

👉🏻Workup algorithm—from benign to suspicious 🦀what’s next?

⭐️A must-know for #Nephrology #Endocrinology #Urology 👩‍⚕️

🔗 doi.org/10.1097/JU.0...

#Incidentaloma #FOAMed #MedSky
#NephSky

💉Immune checkpoint inhibitors: 🦸‍♂️heroes in cancer🦀, 🦹‍♂️villains for kidneys 🫘?

#ICI-AKI can hit both

Glomeruli (C3GN, MCD, vasculitis)
&
Tubulointerstitium (ATIN, ATN, tubulitis)

📖 doi.org/10.34067/KID... 🆕
@asnpublications.bsky.social K360

#Onconephrology #Nephrology #AKI #NephSky #NephPearls

🧰New tools for early ICI-AKI detection!

💧Urine, 🩸 serum, and 📸 imaging markers are changing the game.

Protect kidneys 🫘 , save lives!🌱

🔗 doi.org/10.34067/KID...
@asnpublications.bsky.social K360
@sabinekaram.bsky.social et al

#Nephrology #OncoNephrology #AKI #NephSky #MedSky
#NephPearls

🦀🦴Treatment of Cancer-Associated Hypercalcemia

➡️Start with IV fluids
➡️Then hit osteoclasts with #Bisphosphonates or #Denosumab

But remember, real control = treating the malignancy

🔗 www.nejm.org/doi/full/10....

#Hypercalcemia #Malignancy #OncoNephrology #Nephrology #IM #Oncology #MedSky #NephSky

The CKD-Gut-Immune Axis: A Vicious Cycle 🫘

Uremic toxins → Gut dysbiosis → Inflammation → Immune dysregulation → CKD progression.

Can probiotics break the cycle?

📖 dx.doi.org/10.5527/wjn.... 2025 🆕

#Probiotics #Nephrology #CKD #GutHealth #Uremia #MedSky #NephSky

#Leptospirosis & the #Kidney: A Deadly Duo🦠🫘

Lepto= non-oliguric #AKI→ ATN→ #CKD by blocking Na-K ATPase & inducing vasopressin resistance! Persistent inflammation= fibrosis & kidney failure.

🔗 doi.org/10.1007/s150... 🆕 2025

#Nephrology #InfectiousDiseases #InternalMedicine #MedSky #NephSky

💡Pregnancy after transplant? 🤰🫘🫁🫀
What you need to know!

🔹Pre-pregnancy guidance
🔹Organ-specific outcomes
🔹Risks & expert recommendations

📖 doi.org/10.1097/TP.0... 🆕

@gonikatz.bsky.social @ttsorg.bsky.social (2025)

#TransplantNephrology #Pregnancy #Nephrology #MedTwitter #Transplantation

⚠️Sterile Peritonitis in PD: Think Beyond Infection 🦠

🔍Not always infection!

A broad differential—drugs, malignancy, retrograde menstruation & more! 🏥💡

Freitas et al
🔗https://doi.org/10.1177/089686080502500207

#Nephrology #PeritonealDialysis #PD #MedEd #FOAMed #Dialysis #NephSky #MedSky

🚨Endocrine Hypertension: More Than Just BP🚨

From resistant HTN to adrenal tumors—when should you suspect & how do you approach? 📊🔎

📖Borozan et al., Current Hypertension Reports (2025)
🔗 doi.org/10.1007/s119... 🆕

#Hypertension #Endocrinology #Nephrology #NephSky #MedSky

🚰🔄Vesicoureteral Reflux (VUR): A Silent Threat to Kidneys🫘

From mild reflux to severe tortuosity—grading VUR is key📊

Know when & how to investigate🔍
@diseaseprimers.bsky.social

📖 doi.org/10.1038/s415... (2024-Primer)

#Nephrology #PedsNephro #VUR #UTI #MedEd #FOAMed #NephSky #MedSky

💊🫘Drugs to prevent CKD Progression

doi.org/10.1093/ndt/...

@hjanders.bsky.social

🫘Renal Amyloidosis

academic.oup.com/ndt/article-...

@hjanders.bsky.social

🫘Non invasive biomarkers of Rejection

pubmed.ncbi.nlm.nih.gov/39419272/

@ajkd.bsky.social

Antiphospholipid Syndrome (APS): The Silent Thrombophilia

From molecular pathogenesis to devastating thrombotic complications—#APS is a ticking time bomb! ⏳🧬

📖 APS review: doi.org/10.3390/jcm1... (2025)

#Nephrology #Thrombosis #Lupus #MedTwitter #Rheumatology #Autoimmune

Struggling with hyperphosphatemia in dialysis patients? 🦴🫘

Meet #Tenapanor!

It inhibits paracellular phosphate absorption by modulating NHE3 & tight junctions.

A novel way to tackle phosphorus! 🔬💊

#Nephrology #Hyperphosphatemia #Dialysis #HD

📖https://doi.org/10.1053/j.jrn.2024.07.003