Q&A with Dr. Maitreya Dunham: Reflecting on MSS 2026 and Looking Ahead to the Future of Genome Science
brotmanbaty.org/news/q-and-a...

The image consists of two sections. The top section has text with a header that reads "GENOMICS" followed by the title "Q&A with Dr. Maitreya Dunham: Reflecting on MSS 2026 and Looking Ahead to the Future of Genome Science." Below this is a quote: "Any time is the best time to be in this field." Image is of a person (Maitreya Dunham) with glasses standing at a podium with a microphone.

Fabulous Q&A with Dr. @maitreya.bsky.social @uwgenome.bsky.social "Reflecting on MSS 2026 and Looking Ahead to the Future of Genome Science"
@brotmanbaty.bsky.social @varianteffect.bsky.social #VariantEffect26 ➡️ brotmanbaty.org/news/q-and-a...

🧬 Join the VESS Organizing Committee! We are looking for early-career scientists to help shape our global, community-driven seminar program.
📅 Deadline to apply: April 30, 2026
ℹ️ Learn more and apply👇
forms.gle/vdLh3mu9Fuid...
#VESS #VariantEffects #Seminar #Genomics #EarlyCareer

Here's a better picture of @afrubin.bsky.social's daughter's awesome rendition of my deep mutational scanning experiments as "The Yeast Wars" from my talk at #VariantEffect26 :) Great meeting!

The final speaker of the 2026 Mutational Scanning Symposium is Melissa Call from WEHI (Walter and Eliza Hall Institute of Medical Research). Her talk is covering how mutational profiling of SARS-CoV-2 PLpro exposes inhibitor escape routes.

#VariantEffect26
#AtlasOfVariantEffectsAlliance

Many thanks to all our MSS 2026 sponsors. It's great to have you here!

At the podium now is Joel Geoghegan from Illumina.

#VariantEffect26

On stage now is Alistair Dunham of the Wellcome Sanger Institute with a talk about the standardization and joint analysis of 2041 MAVEs.

#VariantEffect26
#MAVEs
#AtlasOfVariantEffectsAlliance

Next to the stage is Jun Yang of St. Jude Children's Research Hospital - ALSAC. His presentation details MAVE-informed protein language models for predicting pharmacokinetics variant function at scale.

#VariantEffect26
#MAVEs #ProteinLanguageModels
#AtlasOfVariantEffectsAlliance

Our final speaker before morning coffee is Doug Fowler from the University of Washington.

His talk details pathway-scale variant effect mapping in human cells with LABEL-seq.

#VariantEffect26
#LABELseq ##DeepMutationalScanning
#AtlasOfVariantEffectsAlliance

Opening the final day of MSS 2026 is Maitreya Dunham from the University of Washington. Her keynote is entitled, 'From ARS1 to ZWF1: some adventures in deep mutational scanning'.

#VariantEffect26
#DeepMutationalScanning
#AtlasOfVariantEffectsAlliance

Yesterday evening, we enjoyed a fantastic poster session at MSS 2026. There was a real buzz with lots of great conversations!

#VariantEffect26

Taking the stage now is Mark Dawson of the Peter MacCallum Cancer Centre. His talk is about understanding human pathology with base editing at single-cell resolution.

#VariantEffect26
#BaseEditing
#AtlasOfVariantEffectsAlliance

Taking the stage now is Guillaume Diss of the Friedrich Miescher Institute for Biomedical Research. His presentation is about the genetic architecture of protein interaction domain families.

#VariantEffect26
#AtlasOfVariantEffectsAlliance

Everyone's had lunch and chance to begin exploring the posters. So, now we return to the talks!

#VariantEffect26

Many thanks to all our MSS 2026 sponsors. It's great to have you here!

At the podium now is Daniel Zimmerman from Ambry Genetics.

#VariantEffect26

Next to take the stage is Chai Ann (Andy) Ng, of the Victor Chang Cardiac Research Institute. His talk discusses the integration of MAVE and patch clamp data to improve classification and risk prediction in KCNH2-LQTS.

#VariantEffect26
#MAVEs #Cardiology
#AtlasOfVariantEffectsAlliance

Staying on the cardiology theme, we're now hearing from Andrew Glazer of the Vanderbilt University Medical Center. His talk details three multimedia assays of SCN5A variant function informing arrhythmia risk prediction.

#VariantEffect26
#MAVEs #cardiology
#AtlasOfVariantEffectsAlliance

Day 2 of The Mutational Scanning Symposium at the The Aikenhead Centre for Medical Discovery in Melbourne, Australia. We're looking forward to another day of fantastic presentations and posters!

#VariantEffect26
#AtlasOfVariantEffectsAlliance

Opening the second day of talks at MSS 2026 is Prof. Matthew Hurles of the Wellcome Sanger Institute. His talk, 'Scaling MAVEs: Is this the end of the beginning?' discusses progress in efforts to deliver MAVEs at scale.

#VariantEffect26
#MAVEs
#AtlasOfVariantEffectsAlliance

The morning session is well underway at the Mutational Scanning Symposium 2026. Currently speaking is Justine Shih, from the @broadinstitute.org, whose talk is about mapping genetic variation to cellular phenotype.

#VariantEffect26
#AtlasofVariantEffects

Many thanks to all our MSS 2026 sponsors. It's great to have you here.

On the podium now is Bernd Willems from Twist Bioscience.

#VariantEffect26

Photo taken from the rear of a full auditirium. The opening slide of MSS 2026 is displayed on the screen

The Mutational Scanning Symposium 2026 has just opened in Melbourne, Australia. We can't wait to see all the fantastic talks and posters!

#VariantEffect26

Opening the Symposium today is Prof. Fumitaka Inoue of Kyoto University, with his talk, 'Deciphering human functional genome using Massively Parallel Reporter Assays'.

#VariantEffect26
#Genomics #MPRA
#AtlasOfVariantEffectsAlliance

MSS26 Mutational Scanning Symposium 2026, 25-27 March, Melbourne

Registration for MSS26 in Melbourne will close next Monday - we still have a few tickets available, and an amazing line-up of speakers across all areas of variant effects work, so if you were on the fence, check out our program and then smash that "Register now" button!

www.mss2026.org

"Characterizing novel viral proteins using protein language models (PLMs)" -Kieran Lamb YouTube video by Variant Effects

Watch Kieran Lamb's presentation of his work characterizing novel viral proteins using protein language models, as part of our Virology Interest Group's meeting. If you missed it, you can catch up on our YouTube channel: www.youtube.com/watch?v=phrI...

#MAVE #Genomics #Virology #AVE

The image shows the program for the March 3 Variant Effects Seminar Series. More info is available via a QR code or at www.varianteffect.org/seminar-series

If you're a researcher in cancer biology, genetics, structural biology, don't miss tomorrow's seminar on variant characterization and therapeutic implications.

Join the seminar here: tinyurl.com/kj3w35cn
⏰ 9–10 am, Pacific | 12–1 pm, Eastern | 5–6 pm, GMT ⏰

#VariantInterpretation

“THE ONLY THING MORE POWERFUL THAN HATE IS LOVE.”

Let’s go Hawks!! 🏈

Our @varianteffect.bsky.social annual reports summarize, celebrate and showcase our collective work.
Read the latest 🔖 zenodo.org/records/1833...
View them all 📖 www.varianteffect.org/annual-repor... #AnnualReport #GlobalAlliance
#FunctionalGenomics #Consortium

A recent preprint introduces MaveMD, a clinical interface for MaveDB that integrates MAVE data with ClinVar and ClinGen to support variant classification and reduce VUS uncertainty.

Uncover the science behind it:  www.medrxiv.org/content/10.1...