Graphic reads: April 7 | World Health Day Together For Health Standing With Science Three connected circles (from left) 1- image of woman in white coat wearing goggles 2- image of a man in a white coat with a stethoscope around his neck and looking at a child 3- image of several hands together

Science moves us forward. People make it possible.

It takes:
✅ Collaboration.
✅ Innovation.
✅ Community.

What does a healthier world look like to you?

#WorldHealthDay #StandWithScience

This is the third, independent, institution-led clinical study in recent months, expanding the real-world validation of PEDMARK® across new tumor types & patient populations.

#ChemoSideEffects #PatientOutcomes #CanSky

PRESS RELEASE Fennec Pharmaceuticals Announces Investigator-Sponsored Study to be Conducted by University of Arizona Cancer Center

Today we announced the initiation of an IST by University of Arizona Cancer Center to evaluate use of PEDMARK® (sodium thiosulfate injection). Learn more: bit.ly/4mdtNEh

#ClinicalResearch #ComprehensiveCancerCare #OncoSky

Awareness matters – but so does what comes after.

For many testicular cancer patients, #survivorship should include:
✔️Emotional support
✔️Fertility planning
✔️Hearing health monitoring

Let’s keep the conversation going. What does survivorship mean to you? #testicularcancer

#CanSky #OncoSky

PRESS RELEASE Fennec Pharmaceuticals Announces Clinical Research Collaboration with Tampa General Hospital Cancer Institute

We’re pleased to announce that the Tampa General Hospital Cancer Institute is initiating a study to evaluate real-world utility of PEDMARK® (sodium thiosulfate injection).
Learn more: bit.ly/3PfBj4N

#Ototoxicity #ChemoSideEffects #PatientOutcomes #ClinicalResearch #HearingHealth #CancerCare

Hearing connects us — to learning, to independence, to each other.
Acting early matters.
Monitoring matters.
Prevention matters.

This #WorldHearingDay, let’s ensure no young person is left behind.

Cisplatin-induced hearing loss can:
• Be permanent
• Progress over time
• Impact speech & language development
• Affect academic & social outcomes

And for young adults, it can shape education, career paths and quality of life.

FENNEC PHARMA March 3 marks #WorldHearingDay

March 3 is #WorldHearingDay.
This year, @who.int calls us to act now so no child is left behind due to hearing loss.
For children and young adults treated with cisplatin, hearing loss is not a rare side effect — it’s a lifelong consequence.
🧵👇

Behind every person diagnosed with cancer is a network of caregivers: family members, friends & professionals, who provide essential support each day. On #NationalCaregiversDay, and every day, we recognize the critical role caregivers play in the lives of those navigating cancer.

PRESS RELEASE Fennec Pharmaceuticals Presents Real World Data Supporting the Integration and Clinical Use of PEDMARK in Treating Adults with Head and Neck Cancers

We were pleased to present new real-world data in adults with head and neck cancers at the 2026 Multidisciplinary Head and Neck Cancers Symposium.

Read more: investors.fennecpharma.com/news-release...

#CisplatinInducedOtotoxicity #ChemoSideEffects #ClinicalResearch #MHNC26

At the same time, some survivors face lasting effects, such as irreversible hearing loss, which can impact learning, communication & daily life. Today is a moment to honor resilience, acknowledge long-term challenges and continue working toward better outcomes for every child.

On #InternationalChildhoodCancerDay, we recognize children & families whose lives are changed by a cancer diagnosis, and the long journey after treatment ends. Advances in therapy, including cisplatin-based chemotherapy, have improved survival for many childhood & #AYA cancers.

Why is hearing health often overlooked? Tinnitus Awareness Week February 2-8 Image of a gold and silver ribbon

Tinnitus - the perception of noise or ringing in the ears - may be the 1st sign of #CisplatinInducedOtotoxicity (CIO) in some cancer patients undergoing #chemotherapy. Risks of CIO are higher for children & #AYA and the effects can be irreversible.

#TinnitusAwarenessWeek

Image shows words: DESPAIR - LOSS - GRATITUDE - SADNESS - TRUST - CONFUSION - GRIEF - CANCER - LONELINESS - PEACE - COMPASSION - SADNESS - HOPE - STRENGTH - RESILIENCE - PAIN - DOUBT - LOVE - RELIEF - CONNECTION - ANGER - SHOCK - ENDURANCE United in our Triumphs Unique in our Challenges Share Your Story WorldCancerDay.org World Cancer Day 4 February United By Unique

Behind every cancer diagnosis is a unique human story of grief, pain, hope, healing, & resilience. People-centered care means seeing the whole person and meeting their needs through comprehensive care teams to manage treatment-related side effects.

#WorldCancerDay #UnitedByUnique

The 5-year survival rate for all cancers combined is now approximately 69% due to major treatment advances such as platinum-based chemotherapy like cisplatin. However, an unfortunate side effect of cisplatin treatment is irreversible ototoxicity, or hearing loss.

With overall survival rates of all #cancers better than in previous decades, managing side effects of treatment - such as hearing loss from platinum-based #chemotherapy - is more important than ever.

Learn more about this common side effect:
fennecpharma.com/science/cispla

#Ototoxicity

Image of teal and white ribbons for cervical cancer and 4 icons illustrating communication Cervical Cancer Summit Powered by Cervivor January 23, 2026

We’re looking forward to joining experts, patients, survivors, and advocates at the #CervicalCancer Summit powered by #Cervivor in Washington DC this week.

#CervicalCancerAwarenessMonth @cervivor.bsky.social

Photo of Martin Luther King Jr. "If you can't fly then run, if you can't run than walk, if you can't walk then crawl, but whatever you you do you have to keep moving forward."

Today we honor the life of Dr. Martin Luther King, Jr., and his legacy of strength, compassion, and courage. #MLKDay #MLK

Our mission is to help protect hearing for children, adolescents and young adults undergoing treatment for cancer with cisplatin-based chemotherapy, so they can look forward to a future filled with possibility.

#HearingHealth #Ototoxicity #ChemoSideEffects

January 12 National Pharmacists Day

Pharmacists are more than medication experts—they’re trusted advocates & integral members of patient care teams. From administering treatments to managing chronic conditions, pharmacists directly impact patient care.

On #NationalPharmacistsDay, we thank them for all they do!

2025 was a year of building, believing, and delivering.

From advancing science & expanding access, to showing up for patients and families who inspire everything we do, 2025 proved what’s possible when purpose and performance go hand in hand. And we’re just getting started.

Cervical Cancer Awareness Month January

During #CervicalCancerAwarenessMonth, we stand with patients, survivors, and families. Cervical cancer is preventable and treatable when caught early.

With higher survival, quality of life matters—advocate for hearing loss monitoring and prevention.

"Every moment is a new beginning." -Elie Wiesel

The Fennec team wishes everyone a Happy, Healthy & Bright New Year!

Graphic with 'Happy Holidays! surrounding with holiday imagery including ornaments, gift boxes, bows, candles, snowflakes, leaves, flowers, stars and cakes

Happy Holidays from all of us at Fennec!

We wish our colleagues, partners and the people we serve a joy-filled and safe holiday season.

"It just happened, and I had no idea. I would've, at the very least, like to know, like hey, you might lose your hearing. Having it told to me would definitely have been helpful. Like even just mentally preparing myself for something that might happen." -Jake Cancer survivor with cisplatin-induced hearing loss

Cisplatin-based chemotherapy is an effective treatment for #cancer, but some patients and survivors are left with permanent hearing loss, or #ototoxicity, that impacts their quality of life long after treatment ends.

#SoundsOfTheSeason #HearingHealth #ChemoSideEffects

With the holidays approaching, people will soon gather with friends, family, co-workers & even strangers in festivities large & small. There will be music & singing, laughter & conversation, glasses clinking & bells ringing. But not everyone will be able to hear these sounds. 🗣️ 🎄 🎶 🥂

Image of a woman fitting headphones on a child. Text: Audiologists are essential in oncology care Before treatment -Establish a baseline record of hearing and balance During treatment -Administer periodic hearing tests to monitor for any changes, ringing in ears (tinnitus), or balance problems -Communicate with oncology team and suggest treatment options After treatment -Continue to monitor and evaluate

Not being able to fully hear or feeling dizzy can make daily activities challenging. 60 - 90% of #cancer patients develop #ototoxicity from cisplatin-based chemotherapy. Audiological monitoring is an essential component of #oncology care.

#HearingHealth #ComprehensiveCare

PRESS RELEASE Fennec Pharmaceuticals Announces Investigator-Sponsored Trial to be Conducted by City of Hope in Metastatic Testicular Germ Cell Tumors

Today we announced the planned initiation of an IST at @cityofhope.bsky.social to evaluate PEDMARK® (sodium thiosulfate injection) for preventing cisplatin-induced #ototoxicity (CIO) in adult men with stage II-III metastatic testicular germ cell tumors. bit.ly/3KvDPCd #CancerCare #ClinicalResearch

PEDMARK® Study in Japan Shows Significant Reduction in Cisplatin-Related Hearing Loss in Pediatric Patients | Hearing Health & Technology Matters RESEARCH TRIANGLE PARK, N.C. — Fennec Pharmaceuticals Inc. (NASDAQ: FENC; TSX: FRX), a specialty pharmaceutical company, today announced positive topline results from the investigator-initiated Phase ...

“These encouraging results from the first large-scale pediatric and adolescent and young adults (AYA) trial in Japan demonstrate that PEDMARK® can protect hearing without compromising cisplatin’s efficacy or introducing any concerning side effects.” hearinghealthmatters.org/hearing-news... #cancer

International Day of Persons with Disabilities December 3

On #InternationalDayofPersonsWithDisabilities, we honor the strength and resilience of individuals with disabilities.

Promoting their rights and well-being is essential for creating a kinder, more supportive and inclusive society.

#DisabilityRights

PRESS RELEASE Fennec Pharmaceuticals Announces Positive Topline Results from Investigator-Initiated Clinical Study of PEDMARK in Japan to Reduce Cisplatin-Induced Hearing Loss

We announced positive topline results from the investigator-initiated Phase 2/3 STS-J01 clinical trial of PEDMARK® (sodium thiosulfate injection) for the reduction of cisplatin-induced #ototoxicity in pediatric & #AYA patients w/ solid tumors in Japan. Read investors.fennecpharma.com/news-release...