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Posts by Roy Walker

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Hey @natureportfolio.nature.com
is this some sort of joke?? Please act ASAP. This is an abomination! 👇How the hell did this ever pass peer review, editorial processes???
doi.org/10.1038/s415...

2 weeks ago 73 25 10 16
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Building synthetic chromosomes one yeast at a time: insights from Sc2.0 - Nature Biotechnology The Synthetic Yeast Genome Project (Sc2.0) set out to redesign and chemically synthesize an entire eukaryotic genome. This Comment summarizes the design- and construction-related defects revealed duri...

Building synthetic chromosomes one yeast at a time: insights from Sc2.0 - @arccoesb.bsky.social go.nature.com/48Fqxwi

4 months ago 8 3 1 0

Congratulations to our Centre Director Ian Paulsen on being awarded the prestigious Eureka Prize for Leadership in Science! 🎉

This award recognises his outstanding leadership in advancing synthetic biology in Australia and beyond. We couldn’t be prouder of this well-deserved achievement! 👏

7 months ago 6 2 0 0
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Lithium deficiency and the onset of Alzheimer’s disease - Nature Lithium has an essential role in the brain and is deficient early in Alzheimer’s disease, which can be recapitulated in mice and treated with a novel lithium salt that restores the physiological level.

New @nature.com
The possibility that lithium deficiency is a driver of Alzheimer's disease. Experimental model shows Li depletion impedes amyloid clearance, and repletion in humans could be achieved with low doses
nature.com/articles/s41...

8 months ago 458 154 21 24

If interested, feel free to reach out to sbasydneyau[AT]gmail.com. I still plan to be involved and help out as the experience is something I’ve genuinely enjoyed. Of course, this is only for Sydney-based people

8 months ago 0 0 0 0

Time flies! I’m currently looking for a new talented volunteer to lead the Sydney Node of SBA. If you’re interested in gaining some leadership experience, running a team, and organising some fun events, please let me know by the 22nd of August

8 months ago 0 0 1 0
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Pulcherriminic acid Biosynthesis and Transport: Insights from a heterologous system in Saccharomyces cerevisiae Abstract. Pulcherriminic acid is an iron chelator produced by some Kluyveromyces and Metschnikowia yeasts. Its biosynthesis is encoded by the four–gene PUL

New paper out by @aliciamv.bsky.social 🤩🥳

…where we study the yeast-based antifungal compound and iron-chelator pulcherriminic acid

academic.oup.com/femsyr/advan...

8 months ago 7 2 0 0

I’m petrified about today’s science news. Genetically modifying crabs to have cheetah genes? This could go sideways fast.

9 months ago 22503 4083 798 310
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Researchers take first steps to creating synthetic human genomes | Wellcome Scientists are developing technology to create the first synthetic human chromosome. The ability to write large genomes could transform our understanding of health.

It's 25 yrs to the day since the Human Genome Project & Craig Venter declared joint victory in sequencing the human genome - an ideal time for @wellcometrust.bsky.social to annouce their new project, involving our lab, to begin work towards synthesising human genomes. wellcome.org/news/researc...

9 months ago 23 5 1 1
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Scientists at Loughborough University create 'world's smallest violin' The violin is smaller than a human hair and has "laid the groundwork" for future research.

Well this couldn’t have come at a better time www.bbc.com/news/article...

10 months ago 10819 3137 122 202
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Distribution of haploid chromosomes into separate nuclei in two pathogenic fungi Nuclei define eukaryotes, enabling macromolecular compartmentalization and cellular regulation. Each nucleus is believed to contain one or more haploid sets of chromosomes (1N). However, we discovered...

What's going on in fungi?? Chromosomes are distributed across several different nuclei in Sclerotinia sclerotiorum and Botrytis cinerea

Article in @science.org here: www.science.org/doi/10.1126/...
And Perspective here: www.science.org/doi/10.1126/...

11 months ago 39 11 0 0
Uncovering novel methods to elucidate protein secretion in yeast This inter-disciplinary project will apply advanced synthetic biology approaches and genomics to elucidate the genetic basis of protein secretion in yeast.

Dear all – I’m re-sharing this open PhD scholarship. I’ve now managed to secure funding for international PhD entry (and MRes if required). Please email me with a EoI if interested. Thanks!

It's an old ad, but will soon be updated:

www.mq.edu.au/research/phd...

1 year ago 3 0 0 0

Congrats, Daniel! All the best for the new role

1 year ago 1 0 0 0
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Just to prove to everyone that I am working during my sabbatical:

1 year ago 5 1 0 0
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I/We have a fully funded international PhD scholarship in sunny Sydney that’s just come online! This is part of an exciting collaboration between the ARC Centre of Excellence in Synthetic Biology and the Dementia Research Centre. More information here:

www.mq.edu.au/research/phd...

1 year ago 2 0 0 0
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Construction and iterative redesign of synXVI a 903 kb synthetic Saccharomyces cerevisiae chromosome

Full text: www.nature.com/articles/s41...

#yeast #yeastbiology

From @hughiechops.bsky.social

1 year ago 6 3 0 0

A great opportunity if you're in to automation!

1 year ago 0 0 0 0
picture of DNA strand

picture of DNA strand

I am looking for postdoc-level candidates interested in developing a joint application for the Australian National Intelligence Postdoctoral Grants to fund a position within a project on "Designing RNA with Custom Properties using AI". #synbio #ai

More info: www.jaschke-lab.science/opportunitie...

1 year ago 3 5 0 0
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A fantastic full professorship opportunity is now available at the University of Heidelberg - the focus is on various aspects of Synthetic Biology and Synthetic Genomics.

jobs.zeit.de/jobs/full-pr...

1 year ago 3 1 0 0
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I'm a yeast! With thanks

1 year ago 1 0 0 0

I've extended the deadline as I've had surprisingly few applicants! This is a great opportunity to work in a world-class environment as part of the ARC Centre of Excellence in Synthetic Biology. Please note this is not open to international students for now.

1 year ago 1 0 0 0
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Hi – I (we) have an open PhD position for an enthusiastic student in sunny Sydney! Explore new approaches to yeast protein secretion, microfluidics and flow cytometry. Feel free to reach out and apply here. Please note this is for domestic students only. www.mq.edu.au/research/phd...

1 year ago 2 1 1 0

Just testing out BlueSky

Here's a link to our tRNA Neochromosome paper!
www.sciencedirect.com/science/arti...

2 years ago 5 0 0 0