Check out our new paper "UVA Irradiation Promotes ROS-Mediated Formation of the Common Deletion in Mitochondrial DNA" !🧬☀️
▶️https://www.mdpi.com/2075-1729/16/4/577
Congrats to Gabriele Fontana, Navnit Singh, @profshana.bsky.social and co-authors for this achievement !
@mdpiopenaccess.bsky.social
Check out our new paper ➡️ doi.org/10.1007/s002... !
🦠Gut microbial metabolism of hop-polyphenols
🔮Integration into PBK modeling
🧫Estrogenicity of iXN, 8-PN, and mixtures
Congrats to our team members, Maja Stevanoska🎓, @georgaichinger.bsky.social and @profshana.bsky.social !
PhD position alert 📢📢📢
🦠 Emerging mycotoxins - human gut microbiota - molecular mecanisms
🏢 University of Vienna, Institute of Food Chemistry and Toxicology
💌 francesco.crudo@univie.ac.at
#microbiome #PhDPosition #toxicity #science #career #AcademicJobs
Congratulations to Emile Aghajani for her poster "Developing mechanistic and responsive biomarkers of aging based on genome-wide maps of DNA breaks and oxidation" receiving award at #SST2025 ! ✨ @vakil-takhaveev.bsky.social @profshana.bsky.social
#SST2025 presenters from the laboratory of toxicology (3/3):
Navnit Singh - 🧬🧪💥
Alona Slastennikova - 🌱💩🦠
Maja Stevanoska - 💩🦠📉
#SST2025 presenters from the laboratory of toxicology (1/3):
Emilie Aghajani - ⌛👵🧬
Hélène Bigonne - ♀️💻♂️
Blandine Descamps - 🍄🧫💻
Raúl Fernández Cereijo - 💻🦠📈
#SST2025 presenters from the laboratory of toxicology (2/3):
Dr. Jacob Folz - 🦠💩🧪
Jasmin Huber - 🧬✂️👩🔬
Lucie Lefevre - 🧬💻📈
Livia Pietrow - 🧠🧬👵
Huge turnout from our Toxicology Lab at yesterday’s SST meeting. Proud of the team and happy to share our work 💖
Special thanks to the organizers @profshana.bsky.social , Gina Montoya Parra and Laura Suter-Dick ! #SST2025
PhD position alert 📢📢📢
🦠 Impact of microbiome biotransformation on chemical toxicity
🏢 ETH Zürich, Laboratory of toxicology
🧑🔬 @georgaichinger.bsky.social & @profshana.bsky.social
jobs.ethz.ch/job/view/JOP...
#NAMs #microbiome #bioinformatics #PhDPosition #toxicity #science #career #AcademicJobs
New publication alert! Click-code-seq, our DNA-damage sequencing method, is now out! This tool can advance our understanding of aging, cancer and neurodegeneration. Huge thanks to the amazing collaborative team behind this! @sturlalab.bsky.social @ethz.ch
@georgaichinger.bsky.social & @profshana.bsky.social presented at #ICT2025 in Beijing! 🌏
KL “Advancing Chemical Research in Toxicology: From Genotoxicity to Gut Microbial Metabolism”
“Quantifying the Gut Microbiome’s Impact on Toxicokinetics by PBK Modeling.”
#IUTOX2025 @nynkekramer.bsky.social
Click-code-seq reveals how transcription, epigenetics, and aging shape DNA damage in the human genome.
Exciting contribution from our lab at the 8th EU–US Conference on Endogenous DNA Damage and Repair! 🔬🌍
Dr. Vakil Takhaveev (@vakil-takhaveev.bsky.social) presented a great showcase of how innovative sequencing approaches advance our understanding of genome integrity. 💡🧬
Follow the conference live: gsc2025.zohobackstage.in/GlobalScient...
#globalscientificconference #gsc2025 #iitbombay #acs
Another chance to meet Shana Sturla at the Global Scientific Conference 2025! 🙌🏽
Catch her at the ACS Editor session and Friday 9:30 AM session “Proteins & Bioconjugates / Chemical Biology”, which she chairs. 🌍🔬
Great reception to our work in India! 🙌🏽
Shana Sturla presented our research “Mapping chemical modifications throughout the human genome” at the Global Scientific Conference 2025, VMCC IIT Bombay, bringing global experts together to turn discovery into impact. 🌍🔬
If you need information on carcinogenic alkylating agents, check out this amazing new book chapter! 📘✨
Authors: Jasmin Huber, Monika Kojic, Claudia Aloisi, and Shana Sturla 👉 doi.org/10.1016/B978...
Congrats to all authors for this outstanding contribution to the field of molecular toxicology! 👏🧬
🎓 Big congrats to our MSc student Emanuel Schönbächler for successfully defending his thesis: “Expanding Click-Code-Sequencing for Mapping Oxidative and Alkylation DNA Modifications.” 💥🧬
It's finally published in ES&T:
We developed a PBK model for BPA analogues with a multimodal parameterization approach.
👉 yes we can! (predict biokinetics without in vivo data)
👉 analogues reach much higher internal concentrations than BPA
#toxicology #plastics #EDCs
pubs.acs.org/doi/10.1021/...
PhD student Emilie Aghajani and Dr. @vakil-takhaveev.bsky.social represented us at #ARDD2025 in Copenhagen, sharing their work on developing mechanistic biomarkers of aging through genome-wide DNA damage mapping. A fantastic opportunity to connect with the aging research community!
Our fantastic postdoc Vakil Takhaveev (@vakil-takhaveev.bsky.social) rocked the EFMC Young Medicinal Chemists’ Symposium in Porto 🇵🇹 @euromedchem.bsky.social, presenting how DNA-damage sequencing can reveal anti-cancer drug mechanisms and push precision oncology forward! ✨🧬
🌍 Our team had the privilege to showcase our latest advances in developing #NAMs under the equator at #WC13! ✨
🔬 @georgaichinger.bsky.social – microbiome-competent biokinetic modeling
🧪 Blandine Descamps – prediction of emerging mycotoxins toxicokinetics
⚖️ Hélène Bigonne – sex-informed PBK models
✨ Our lab members Nina Frei, Jasmin Huber, and Lucie Lefevre had an inspiring day at the SCS Fall Meeting 2025 @swisschemistry.bsky.social in Zürich! It was a fantastic opportunity to exchange ideas, discover cutting-edge research, and connect with the vibrant Swiss chemistry community. 🌍🔬💡
Great discussions at the #Metabolomics2025 in Prague ! ✨
Our brilliant postdoc Jacob Folz presented his research on "Quantifying rate and global profile of gut microbiota metabolism ex vivo by LC-MS/MS". 🦠
Stay tuned - his new publication is on the way ! 😉
Quite a day at the Annual Meeting of the Swiss Society of Toxicology with talks by @georgaichinger.bsky.social (microbiome-competent PK modeling) & @vakil-takhaveev.bsky.social (DNA damage sequencing).
Special Congrats to PhDs Alona Slastennikova and Blandine Descamps who received poster awards!💪🥳